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There are a lack of targeted, safe, and effective therapies. Percutaneous electrical nerve field stimulation (PENFS) is a nonpharmacologic neurostimulation device that targets vagal pathways via the external auricle. Four-week cycles of PENFS therapy have demonstrated efficacy for various abdominal pain\u2013related DGBI in children. PENFS has a high safety profile with minimal side effects in large cohort studies. Although access remains challenging because of the need for device placements by certified clinicians along with limited reimbursement, auricular PENFS is a promising, noninvasive, and targeted therapy for pediatric DGBI with underlying autonomic dysregulation.<\/jats:p>","DOI":"10.1542\/peds.2026-077344","type":"journal-article","created":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T00:03:07Z","timestamp":1785888187000},"source":"Crossref","is-referenced-by-count":0,"title":["Auricular Neurostimulation: A Novel Therapy for Abdominal Pain-Related Disorders of Gut-Brain Interaction"],"prefix":"10.1542","volume":"158","author":[{"given":"Lauren","family":"Hagenstein","sequence":"first","affiliation":[{"name":"1Department of Pediatrics, Medical College of Wisconsin, Milwaukee, Wisconsin"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katja","family":"Karrento","sequence":"additional","affiliation":[{"name":"2Division of Pediatric Gastroenterology, Hepatology, and 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