{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T12:38:46Z","timestamp":1767184726146,"version":"build-2238731810"},"reference-count":0,"publisher":"American Academy of Pediatrics (AAP)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1996,1,1]]},"abstract":"<jats:p>Staphylococcal Scalded Skin Syndrome (SSSS) is the most severe manifestation in the spectrum of Staphylococcus aureus exotoxin-mediated disease in skin. The disease is characterized by erythema and exfoliation and is mediated by exotoxins elaborated primarily by phage group II S aureus.<\/jats:p>\n                  <jats:p>SSSS affects children, especially infants. Both sporadic and epidemic cases occur. Older children and adults rarely are affected. Immature renal function, leading to a reduced ability to clear bacterial exotoxin, may account for the increased susceptibility of neonates, according to Elias and Fritsch. Renal and immunologic dysfunction predispose to the disease in older individuals.<\/jats:p>\n                  <jats:p>SSSS begins abruptly with tender erythema of the skin. Within 12 to 14 hours, the attachment between the stratum corneum and underlying epidermis becomes weak.<\/jats:p>","DOI":"10.1542\/pir.17.1.18","type":"journal-article","created":{"date-parts":[[2021,12,10]],"date-time":"2021-12-10T21:31:43Z","timestamp":1639171903000},"page":"18-18","source":"Crossref","is-referenced-by-count":3,"title":["Staphylococcal Scalded Skin Syndrome"],"prefix":"10.1542","volume":"17","author":[{"given":"Shoshannah","family":"Pollack","sequence":"first","affiliation":[{"name":"Albert Einstein College of Medicine, Bronx, NY"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"417","published-online":{"date-parts":[[1996,1,1]]},"container-title":["Pediatrics In Review"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/publications.aap.org\/pediatricsinreview\/article-pdf\/17\/1\/18\/990778\/18.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/publications.aap.org\/pediatricsinreview\/article-pdf\/17\/1\/18\/990778\/18.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,21]],"date-time":"2021-12-21T09:37:37Z","timestamp":1640079457000},"score":1,"resource":{"primary":{"URL":"https:\/\/publications.aap.org\/pediatricsinreview\/article\/17\/1\/18\/36104\/Staphylococcal-Scalded-Skin-Syndrome"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1996,1,1]]},"references-count":0,"aliases":["10.1542\/pir.17-1-18"],"journal-issue":{"issue":"1","published-online":{"date-parts":[[1996,1,1]]},"published-print":{"date-parts":[[1996,1,1]]}},"URL":"https:\/\/doi.org\/10.1542\/pir.17.1.18","relation":{},"ISSN":["0191-9601","1526-3347"],"issn-type":[{"value":"0191-9601","type":"print"},{"value":"1526-3347","type":"electronic"}],"subject":[],"published":{"date-parts":[[1996,1,1]]}}}