{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T12:08:20Z","timestamp":1790424500406,"version":"4.1.0"},"reference-count":41,"publisher":"American Academy of Pediatrics (AAP)","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2008,11,1]]},"DOI":"10.1542\/pir.29.11.e59","type":"journal-article","created":{"date-parts":[[2021,12,9]],"date-time":"2021-12-09T19:38:35Z","timestamp":1639078715000},"page":"e59-e65","source":"Crossref","is-referenced-by-count":95,"title":["Transient Tachypnea of the Newborn"],"prefix":"10.1542","volume":"29","author":[{"given":"Lokesh","family":"Guglani","sequence":"first","affiliation":[{"name":"Department of Pediatrics, University at Buffalo, Women and Children's Hospital of Buffalo, Buffalo, NY"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satyan","family":"Lakshminrusimha","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University at Buffalo, Women and Children's Hospital of Buffalo, Buffalo, NY"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rita M.","family":"Ryan","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University at Buffalo, Women and Children's Hospital of Buffalo, Buffalo, NY"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"417","published-online":{"date-parts":[[2008,11,1]]},"reference":[{"key":"2021120906181933300_R1","doi-asserted-by":"crossref","unstructured":"Lowe NK, Reiss R. Parturition and fetal adaptation. J Obstetr Gyn Neonat Nurs.\u20081996;25:339\u2013349","DOI":"10.1111\/j.1552-6909.1996.tb02580.x"},{"key":"2021120906181933300_R2","unstructured":"Liggins GC. Growth of the fetal lung. J Dev Physiol.\u20081984;6:237\u2013248"},{"key":"2021120906181933300_R3","doi-asserted-by":"crossref","unstructured":"Strang LB. Fetal lung liquid: secretion and reabsorption. Physiol Rev.\u20081991;71:991\u20131016","DOI":"10.1152\/physrev.1991.71.4.991"},{"key":"2021120906181933300_R4","doi-asserted-by":"crossref","unstructured":"Adamson TM, Brodecky V, Lambert TF, et al. Lung liquid production and composition in the \u201cin utero\u201d foetal lamb. Aust J Exp Biol Med Sci.\u20081975;53:65\u201375","DOI":"10.1038\/icb.1975.7"},{"key":"2021120906181933300_R5","unstructured":"Jost PA, Policard A. Contribution experimentale a L'etude du developpement prenatal du poumon chez le lapin. Arch D'Anatomie Microscopique.\u20081948;37:323\u2013332"},{"key":"2021120906181933300_R6","doi-asserted-by":"crossref","unstructured":"Brown MJ, Olver RE, Ramsden CA, et al. Effects of adrenaline and of spontaneous labour on the secretion and absorption of lung liquid in the fetal lamb. J Physiol.\u20081983;344:137\u2013152","DOI":"10.1113\/jphysiol.1983.sp014929"},{"key":"2021120906181933300_R7","unstructured":"Souza P, O'Brodovich H, Post M. Lung fluid restriction affects growth, but not airway branching of embryonic rat lung. Int J Dev Biol.\u20081995;39:629\u2013637"},{"key":"2021120906181933300_R8","doi-asserted-by":"crossref","unstructured":"Elias N, O'Brodovich H. Clearance of fluid from airspaces of newborns and infants. NeoReviews.\u20082006;7:e88\u2013e93","DOI":"10.1542\/neo.7-2-e88"},{"key":"2021120906181933300_R9","doi-asserted-by":"crossref","unstructured":"Kitterman JA, Ballard PL, Clements JA, et al. Tracheal fluid in fetal lambs: spontaneous decrease prior to birth. J Appl Physiol.\u20081979;47:985\u2013989","DOI":"10.1152\/jappl.1979.47.5.985"},{"key":"2021120906181933300_R10","doi-asserted-by":"crossref","unstructured":"Jain L. Alveolar fluid clearance in developing lungs and its role in neonatal transition. Clin Perinatol.\u20081999;26:585\u2013599","DOI":"10.1016\/S0095-5108(18)30038-1"},{"key":"2021120906181933300_R11","doi-asserted-by":"crossref","unstructured":"Olver RE, Ramsden CA, Strang LB, et al. The role of amiloride-blockable sodium transport in adrenaline-induced lung liquor reabsorption in the fetal lamb. J Physiol.\u20081986;376:321\u2013340","DOI":"10.1113\/jphysiol.1986.sp016156"},{"key":"2021120906181933300_R12","doi-asserted-by":"crossref","unstructured":"Niisato N, Ito Y, Marunaka Y. cAMP stimulates Na+ transport in rat fetal pneumocyte: involvement of a PTK- but not a PKA-dependent pathway. Am J Physiol Lung Cell Mol Physiol.\u20081999;277:L727\u2013L736","DOI":"10.1152\/ajplung.1999.277.4.L727"},{"key":"2021120906181933300_R13","doi-asserted-by":"crossref","unstructured":"Norlin A, Folkensson HG. Ca2+-dependent stimulation of alveolar fluid clearance in near-term fetal guinea pigs. Am J Physiol Lung Cell Mol Physiol.\u20082002;282:L642\u2013L649","DOI":"10.1152\/ajplung.00417.2000"},{"key":"2021120906181933300_R14","doi-asserted-by":"crossref","unstructured":"O'Brodovich H, Hannam V, Seear M, et al. Amiloride impairs lung water clearance in newborn guinea pigs. J Appl Physiol.\u20081990;68:1758\u20131762","DOI":"10.1152\/jappl.1990.68.4.1758"},{"key":"2021120906181933300_R15","doi-asserted-by":"crossref","unstructured":"Field DJ, Milner AD, Hopkin IE, et al. Changing patterns in neonatal respiratory diseases. Pediatr Pulmonol.\u20081987;3:231\u2013235","DOI":"10.1002\/ppul.1950030407"},{"key":"2021120906181933300_R16","doi-asserted-by":"crossref","unstructured":"Morrison JJ, Rennie JM, Milton PJ. Neonatal respiratory morbidity and mode of delivery at term: influence of timing of elective cesarean section. BJOG.\u20081995;102:101\u2013106","DOI":"10.1111\/j.1471-0528.1995.tb09060.x"},{"key":"2021120906181933300_R17","doi-asserted-by":"crossref","unstructured":"Dani C, Reali MF, Bertini G, et al. Risk factors for the development of respiratory distress syndrome and transient tachypnea in newborn infants. Eur Resp J.\u20081999;14:155\u2013159","DOI":"10.1034\/j.1399-3003.1999.14a26.x"},{"key":"2021120906181933300_R18","doi-asserted-by":"crossref","unstructured":"Tudehope DI, Smyth MH. Is transient tachypnea of newborn always a benign condition? Report of 6 babies requiring mechanical ventilation. Austr Pediatr J.\u20081979;15:160\u2013165","DOI":"10.1111\/j.1440-1754.1979.tb01215.x"},{"key":"2021120906181933300_R19","doi-asserted-by":"crossref","unstructured":"Hjalmarson O. Epidemiology and classification of acute neonatal respiratory disorders \u2013 a prospective study. Acta Pediatr Scand.\u20081981;70:773\u2013783","DOI":"10.1111\/j.1651-2227.1981.tb06228.x"},{"key":"2021120906181933300_R20","doi-asserted-by":"crossref","unstructured":"Brice JE, Walker CH. Changing pattern of respiratory distress in the newborn. Lancet.\u20081977;2:752\u2013754","DOI":"10.1016\/S0140-6736(77)90249-5"},{"key":"2021120906181933300_R21","unstructured":"Greenough A. Transient tachypnea of newborn. In: Chernick V, Boat TF, Wilmott RW, Bush A, eds. Kendig's Disorders of the Respiratory Tract in Children. Philadelphia, Pa: Saunders Elsevier; 2006:325\u2013326"},{"key":"2021120906181933300_R22","doi-asserted-by":"crossref","unstructured":"Morrison JJ, Rennie JM. Neonatal respiratory morbidity and mode of delivery at term: influence of timing of elective caesarean section. Br J Obstet Gynaecol.\u20081995;102:101\u2013106","DOI":"10.1111\/j.1471-0528.1995.tb09060.x"},{"key":"2021120906181933300_R23","doi-asserted-by":"crossref","unstructured":"Jain L. Respiratory morbidity in late-preterm infants: prevention is better than cure!Am J Perinatol.\u20082008;25:75\u201378","DOI":"10.1055\/s-2007-1022471"},{"key":"2021120906181933300_R24","doi-asserted-by":"crossref","unstructured":"Zanardo V, Simbi AK, Franzoi M, et al. Neonatal respiratory morbidity risk and mode of delivery at term: influence of timing of elective caesarean delivery. Acta Paediatr.\u20082004;93:643\u2013647","DOI":"10.1111\/j.1651-2227.2004.tb02990.x"},{"key":"2021120906181933300_R25","doi-asserted-by":"crossref","unstructured":"Kasap B, Duman N, Ozer E, et al. Transient tachypnea of the newborn: predictive factor for prolonged tachypnea. Pediatr Int.\u20082008;50:81\u201384","DOI":"10.1111\/j.1442-200X.2007.02535.x"},{"key":"2021120906181933300_R26","doi-asserted-by":"crossref","unstructured":"Yost GC, Young PC, Buchi KF. Significance of grunting respirations in infants admitted to a well-baby nursery. Arch Pediatr Adol Med.\u20082001;155:372\u2013375","DOI":"10.1001\/archpedi.155.3.372"},{"key":"2021120906181933300_R27","unstructured":"Greenough A. Transient tachypnea of the newborn (TTN). In: Greenough A, Milner AD, eds. Neonatal Respiratory Disorders. London, England: Arnold Publishers; 2003:272\u2013277"},{"key":"2021120906181933300_R28","doi-asserted-by":"crossref","unstructured":"Cleveland RH. A radiologic update on medical diseases of the newborn chest. Pediatr Radiol.\u20081995;25:631\u2013637","DOI":"10.1007\/BF02011835"},{"key":"2021120906181933300_R29","doi-asserted-by":"crossref","unstructured":"Kurl S, Heinonen KM, Kiekara O. The first chest radiograph in neonates exhibiting respiratory distress at birth. Clin Pediatr.\u20081997;36:285\u2013289","DOI":"10.1177\/000992289703600506"},{"key":"2021120906181933300_R30","doi-asserted-by":"crossref","unstructured":"Lee S, Hassan A, Ingram D, et al. Effects of different modes of delivery on lung volumes of newborn infants. Pediatr Pulmonol.\u20081999;27:318\u2013321","DOI":"10.1002\/(SICI)1099-0496(199905)27:5<318::AID-PPUL4>3.0.CO;2-E"},{"key":"2021120906181933300_R31","doi-asserted-by":"crossref","unstructured":"Faxelius G, Hagnevik K, Lagercrantz H, et al. Catecholamine surge and lung function after delivery. Arch Dis Child.\u20081983;58:262\u2013266","DOI":"10.1136\/adc.58.4.262"},{"key":"2021120906181933300_R32","doi-asserted-by":"crossref","unstructured":"Sandberg KSB, Hjalmarson O, Olsson T. Lung function in newborns with tachypnea of unknown cause. Pediatr Res.\u20081987;22:581\u2013586","DOI":"10.1203\/00006450-198711000-00020"},{"key":"2021120906181933300_R33","doi-asserted-by":"crossref","unstructured":"Schatz M, Zeiger RS, Hoffman CP, et al. Increased transient tachypnea of the newborn in infants of asthmatic mothers. Am J Dis Child.\u20081991;145:156\u2013158","DOI":"10.1001\/archpedi.1991.02160020046013"},{"key":"2021120906181933300_R34","doi-asserted-by":"crossref","unstructured":"Demissie K, Marcella SW, Breckenridge MB, et al. Maternal asthma and transient tachypnea of the newborn. Pediatrics.\u20081998;102:84\u201390","DOI":"10.1542\/peds.102.1.84"},{"key":"2021120906181933300_R35","doi-asserted-by":"crossref","unstructured":"Schaubel D, Johansen H, Dutta M, et al. Neonatal characteristics as risk factors for preschool asthma. J Asthma.\u20081996;33:255\u2013264","DOI":"10.3109\/02770909609055366"},{"key":"2021120906181933300_R36","doi-asserted-by":"crossref","unstructured":"Birnkrant DJ, Picone C, Markowitz W, et al. Association of transient tachypnea of the newborn and childhood asthma. Pediatr Pulmonol.\u20082006;41:978\u2013984","DOI":"10.1002\/ppul.20481"},{"key":"2021120906181933300_R37","unstructured":"Hein HA, Ely JW, Lofgren MA. Neonatal respiratory distress in the community hospital: when to transport, when to keep. J Fam Pract.\u20081998;46:284\u2013289"},{"key":"2021120906181933300_R38","doi-asserted-by":"crossref","unstructured":"Jain L, Dudell GG. Respiratory transition in infants delivered by cesarean section. Semin Perinatol.\u20082006;30:296\u2013304","DOI":"10.1053\/j.semperi.2006.07.011"},{"key":"2021120906181933300_R39","doi-asserted-by":"crossref","unstructured":"Wiswell TE, Rawlings JS, Smith FR, et al. Effect of furosemide on the clinical course of transient tachypnea of the newborn. Pediatrics.\u20081985;75:908\u2013910","DOI":"10.1542\/peds.75.5.908"},{"key":"2021120906181933300_R40","doi-asserted-by":"crossref","unstructured":"Kao B, Stewart de Ramirez SA, Belfort MB, Hansen A. Inhaled epinephrine for the treatment of transient tachypnea of the newborn. J Perinatol.\u20082008;28:205\u2013210","DOI":"10.1038\/sj.jp.7211917"},{"key":"2021120906181933300_R41","doi-asserted-by":"crossref","unstructured":"Stutchfield P, Whitaker R, Russell I, et al. Antenatal betamethasone and incidence of neonatal respiratory distress after elective caesarean section: pragmatic randomised trial. BMJ.\u20082005;331:662","DOI":"10.1136\/bmj.38547.416493.06"}],"container-title":["Pediatrics In Review"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/publications.aap.org\/pediatricsinreview\/article-pdf\/29\/11\/e59\/997071\/zpx01108000e59.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/publications.aap.org\/pediatricsinreview\/article-pdf\/29\/11\/e59\/997071\/zpx01108000e59.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,17]],"date-time":"2023-01-17T16:07:00Z","timestamp":1673971620000},"score":1,"resource":{"primary":{"URL":"https:\/\/publications.aap.org\/pediatricsinreview\/article\/29\/11\/e59\/33955\/Transient-Tachypnea-of-the-Newborn"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,11,1]]},"references-count":41,"aliases":["10.1542\/pir.29-11-e59"],"journal-issue":{"issue":"11","published-online":{"date-parts":[[2008,11,1]]},"published-print":{"date-parts":[[2008,11,1]]}},"URL":"https:\/\/doi.org\/10.1542\/pir.29.11.e59","relation":{},"ISSN":["0191-9601","1526-3347"],"issn-type":[{"value":"0191-9601","type":"print"},{"value":"1526-3347","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,11,1]]}}}