{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T04:43:36Z","timestamp":1768279416335,"version":"3.49.0"},"reference-count":0,"publisher":"Radcliffe Medical Media Ltd","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:p>Pulmonary vein isolation (PVI) has been demonstrated to be a highly effective treatment option for patients with paroxysmal atrial fibrillation (AF), but less effective for patients with persistent AF. The lower efficacy of PVI alone has been attributed to adverse atrial electrical and structural remodelling in the setting of AF. Strategies to improve efficacy of catheter ablation for persistent AF alter these pathophysiological characteristics of atrial tissue remodelling. Here we will review the physiology of atrial electrical remodelling observed during AF and evidence that it is reversible. Further, we will explore its uses to reduce the amount of atrial tissue that needs to be ablated to successfully treat patients with persistent AF.<\/jats:p>","DOI":"10.15420\/aer.2014.3.2.101","type":"journal-article","created":{"date-parts":[[2014,8,27]],"date-time":"2014-08-27T14:53:40Z","timestamp":1409151220000},"page":"101","source":"Crossref","is-referenced-by-count":5,"title":["Limited Ablation for Persistent Atrial Fibrillation Using Preprocedure Reverse Remodelling"],"prefix":"10.15420","volume":"3","author":[{"given":"David","family":"Slotwiner","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathan","family":"Steinberg","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Assistant Professor of Cardiology, Hofstra North Shore-LIJ School of Medicine, and Associate Director \u2013 Cardiac Electrophysiology Laboratory, Long Island Jewish Medical Center, North Shore-LIJ Health System, 270-05 76th Ave, New Hyde Park, NY 11040, US. E: dslotwin@NSHS.edu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Adjunct Professor of Medicine, University of Rochester School of Medicine, and Director, Arrhythmia Institute, The Valley Health System, New York and New Jersey, USA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"6096","container-title":["Arrhythmia &amp; Electrophysiology Review"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.aerjournal.com\/articleindex\/aer.2014.3.2.101","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,6,10]],"date-time":"2021-06-10T13:55:44Z","timestamp":1623333344000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.aerjournal.com\/articleindex\/aer.2014.3.2.101"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2014]]}},"alternative-id":["articles\/limited-ablation-persistent-atrial-fibrillation-using-preprocedure-reverse-remodelling"],"URL":"https:\/\/doi.org\/10.15420\/aer.2014.3.2.101","relation":{},"ISSN":["2050-3377"],"issn-type":[{"value":"2050-3377","type":"print"}],"subject":[],"published":{"date-parts":[[2014]]}}}