{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T08:08:32Z","timestamp":1787731712510,"version":"build-2784847793"},"reference-count":0,"publisher":"Radcliffe Medical Media Ltd","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arrhythm Electrophysiol Rev"],"published-print":{"date-parts":[[2014]]},"abstract":"Atrial septal defects (ASDs) are among the most common of congenital\n heart defects and are frequently associated with atrial arrhythmias. Atrial\n and ventricular geometrical remodelling secondary to the intracardiac shunt\n promotes evolution of the electrical substrate, predisposing the patient to\n atrial fibrillation and other arrhythmias. Closure of an ASD reduces the\n immediate and long-term prevalence of atrial arrhythmias, but the evidence\n suggests that patients remain at an increased long-term risk in comparison\n with the normal population. The closure technique itself and its timing\n impacts future arrhythmia risk profile while subsequent transseptal access\n following surgical or device closure is complicated. Newer techniques\n combined with increased experience will help to alleviate some of the\n difficulties associated with optimal management of arrhythmias in these\n patients.<\/jats:p>","DOI":"10.15420\/aer.2014.3.3.168","type":"journal-article","created":{"date-parts":[[2014,12,1]],"date-time":"2014-12-01T11:01:49Z","timestamp":1417431709000},"page":"168","source":"Crossref","is-referenced-by-count":52,"title":["Pathophysiology and Management of Arrhythmias Associated with Atrial\n Septal Defect and Patent Foramen Ovale"],"prefix":"10.15420","volume":"3","author":[{"given":"Henry","family":"Chubb","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Whitaker","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven E","family":"Williams","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine E","family":"Head","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natali AY","family":"Chung","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew J","family":"Wright","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"O\u2019Neill","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Division of\n Imaging Sciences and Biomedical Engineering, King\u2019s College London;\n Department of Paediatric Cardiology, Evelina London Children\u2019s\n Hospital","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Division of\n Imaging Sciences and Biomedical Engineering, King\u2019s College\n London","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Division of\n Imaging Sciences and Biomedical Engineering, King\u2019s College London;\n Adult Congenital Heart Disease Group, Department of Cardiology, Guy\u2019s\n and St Thomas\u2019 NHS Foundation Trust and Evelina London\n Children\u2019s Hospital, London, UK","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Adult Congenital\n Heart Disease Group, Department of Cardiology, Guy\u2019s and St\n Thomas\u2019 NHS Foundation Trust and Evelina London Children\u2019s\n Hospital, London, UK","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Adult Congenital\n Heart Disease Group, Department of Cardiology, Guy\u2019s and St\n Thomas\u2019 NHS Foundation Trust and Evelina London Children\u2019s\n Hospital, London, UK","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Division of\n Imaging Sciences and Biomedical Engineering, King\u2019s College\n London","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Division of\n Imaging Sciences and Biomedical Engineering and Cardiovascular Medicine,\n King\u2019s College London, 4th Floor, North Wing, St Thomas\u2019\n Hospital, Westminster Bridge Road, London, SE1 7EH, UK. E:\n mark.oneill@kcl.ac.uk; Adult Congenital Heart Disease Group, Department of\n Cardiology, Guy\u2019s and St Thomas\u2019 NHS Foundation Trust and\n Evelina London Children\u2019s Hospital, London, UK","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"6096","container-title":["Arrhythmia & Electrophysiology Review"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.aerjournal.com\/articleindex\/aer.2014.3.3.168","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,6,10]],"date-time":"2021-06-10T09:55:50Z","timestamp":1623318950000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.aerjournal.com\/articleindex\/aer.2014.3.3.168"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":0,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2014]]}},"alternative-id":["articles\/pathophysiology-and-management-arrhythmias-associated-atrial-septal-defect-and-patent"],"URL":"https:\/\/doi.org\/10.15420\/aer.2014.3.3.168","relation":{},"ISSN":["2050-3377","2050-3369"],"issn-type":[{"value":"2050-3377","type":"electronic"},{"value":"2050-3369","type":"print"}],"subject":[],"published":{"date-parts":[[2014]]}}}