{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T15:02:10Z","timestamp":1753887730394,"version":"3.41.2"},"reference-count":21,"publisher":"Radcliffe Medical Media Ltd","license":[{"start":{"date-parts":[[2025,4,28]],"date-time":"2025-04-28T00:00:00Z","timestamp":1745798400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/legalcode"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arrhythm Electrophysiol Rev"],"abstract":"<jats:p>Three patients, two women and one man, aged 50.0\u00a0\u00b1\u00a09.8\u00a0years, who underwent catheter ablation for typical atrioventricular nodal re-entrant tachycardia, were studied during sinus rhythm. An electroanatomic system suitable for high-resolution mapping and recording of both bipolar and unipolar electrograms was used. Recording of potentials from the area of the right inferior extension was feasible in all patients with bipolar signals. Using unipolar signals, the electrical activity of the atrioventricular node was recorded in all patients. This preliminary report supports the existing evidence that the activity of the atrioventricular node and its right inferior extension can be successfully mapped in the electrophysiology lab.<\/jats:p>","DOI":"10.15420\/aer.2024.34","type":"journal-article","created":{"date-parts":[[2025,4,29]],"date-time":"2025-04-29T09:59:29Z","timestamp":1745920769000},"source":"Crossref","is-referenced-by-count":0,"title":["Electroanatomic Mapping of the Atrioventricular Node and Right Inferior Nodal Extension: Insights from a Case Series"],"prefix":"10.15420","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4125-9516","authenticated-orcid":false,"given":"George","family":"Katritsis","sequence":"first","affiliation":[{"name":"Royal Brompton and Harefield Hospital NHS Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-5355-6170","authenticated-orcid":false,"given":"George","family":"Stavropoulos","sequence":"additional","affiliation":[{"name":"Second Cardiology Department, Aristotle University of Thessaloniki, Hippokration General Hospital, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7158-4950","authenticated-orcid":false,"given":"Nikolaos","family":"Fragakis","sequence":"additional","affiliation":[{"name":"Second Cardiology Department, Aristotle University of Thessaloniki, Hippokration General Hospital, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"6096","published-online":{"date-parts":[[2025,4,28]]},"reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"Pandozi C, Matteucci A, Galeazzi M, et al. 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Miniseries 1-Part IV: how frequent are fasciculo-ventricular connections in the normal heart? Europace 2022;24:464\u201372. https:\/\/doi.org\/10.1093\/europace\/euab286; PMID:\u00a034999781.","DOI":"10.1093\/europace\/euab286"},{"key":"ref10","doi-asserted-by":"publisher","unstructured":"Katritsis D, Tretter JT, Marine JE, et al. Quantitative assessment of the fast pathway in atrioventricular nodal reentrant tachycardia. J Interv Card Electrophysiol 2023;66:991\u20136. https:\/\/doi.org\/10.1007\/s10840-022-01408-5; PMID:\u00a036355272.","DOI":"10.1007\/s10840-022-01408-5"},{"key":"ref11","doi-asserted-by":"publisher","unstructured":"Kawashima T, Sasaki H. Gross anatomy of the human cardiac conduction system with comparative morphological and developmental implications for human application. Ann Anat 2011;193:1\u201312. https:\/\/doi.org\/10.1016\/j.aanat.2010.11.002; PMID:\u00a021145220.","DOI":"10.1016\/j.aanat.2010.11.002"},{"key":"ref12","doi-asserted-by":"publisher","unstructured":"Hucker WJ, McCain ML, Laughner JI, et al. Connexin 43 expression delineates two discrete pathways in the human atrioventricular junction. Anat Rec (Hoboken) 2008;291:204\u201315. https:\/\/doi.org\/10.1002\/ar.20631; PMID:\u00a018085635.","DOI":"10.1002\/ar.20631"},{"key":"ref13","doi-asserted-by":"publisher","unstructured":"Kurian T, Ambrosi C, Hucker W, et al. Anatomy and electrophysiology of the human AV node. Pacing Clin Electrophysiol 2010;33:754\u201362. https:\/\/doi.org\/10.1111\/j.1540-8159.2010.02699.x; PMID:\u00a020180918.","DOI":"10.1111\/j.1540-8159.2010.02699.x"},{"key":"ref14","doi-asserted-by":"publisher","unstructured":"Meijler FL, Janse MJ. Morphology and electrophysiology of the mammalian atrioventricular node. 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Heart Rhythm 2022;19:548\u201359. https:\/\/doi.org\/10.1016\/j.hrthm.2021.12.006; PMID:\u00a034896623.","DOI":"10.1016\/j.hrthm.2021.12.006"},{"key":"ref18","doi-asserted-by":"publisher","unstructured":"Efimov IR, Nikolski VP, Rothenberg F, et al. Structure\u2013function relationship in the AV junction. Anat Rec A Discov Mol Cell Evol Biol 2004;280:952\u201365. https:\/\/doi.org\/10.1002\/ar.a.20108; PMID:\u00a015368340.","DOI":"10.1002\/ar.a.20108"},{"key":"ref19","unstructured":"Katz AM. Physiology of the heart. 3rd ed. Philadelphia, US: Lippincott, Williams, & Wilkins, 2001."},{"key":"ref20","doi-asserted-by":"publisher","unstructured":"Kupersmith J, Krongrad E, Waldo AL. Conduction intervals and conduction velocity in the human cardiac conduction system. Studies during open-heart surgery. 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