{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T14:09:22Z","timestamp":1776866962954,"version":"3.51.2"},"reference-count":76,"publisher":"Radcliffe Medical Media Ltd","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018]]},"abstract":"<jats:p>Heart failure (HF) is a complex disease with a growing incidence worldwide. HF is accompanied by a wide range of conditions which affect disease progression, functional performance and contribute to growing healthcare costs. The interactions between a failing myocardium and altered cerebral functions contribute to the symptoms experienced by patients with HF, affecting many comorbidities and causing a poor prognosis. This article provides a condensed version of the 2018 position paper from the Study Group on Heart and Brain Interaction of the Heart Failure Association. It addresses the reciprocal impact on HF of several pathological brain conditions, including acute and chronic low perfusion of the brain, and impairment of higher cortical and brain stem functions. Treatment-related interactions \u2013 medical, interventional and device-related \u2013 are also discussed.<\/jats:p>","DOI":"10.15420\/cfr.2018.14.2","type":"journal-article","created":{"date-parts":[[2018,8,23]],"date-time":"2018-08-23T15:52:20Z","timestamp":1535039540000},"page":"87","source":"Crossref","is-referenced-by-count":38,"title":["Heart\u2013brain Interactions in Heart Failure"],"prefix":"10.15420","volume":"4","author":[{"given":"Nadja","family":"Scherbakov","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wolfram","family":"Doehner","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Centre for Stroke Research Berlin, Charit\u00e9 University Hospital, Berlin, Germany","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"German Centre for Heart and Cardiovascular Research (DZHK), Partner Site Berlin, Charit\u00e9 University Hospital, Berlin, Germany","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Centre for Stroke Research Berlin, Charit\u00e9 University Hospital, Berlin, Germany","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"German Centre for Heart and Cardiovascular Research (DZHK), Partner Site Berlin, Charit\u00e9 University Hospital, Berlin, Germany","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Division of Cardiology and Metabolism, Department of Cardiology, Charit\u00e9 University Hospital, Berlin, Germany","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"6096","reference":[{"key":"ref0","doi-asserted-by":"publisher","first-page":"966","DOI":"10.1136\/heartjnl-2017-312814","article-title":"Socioeconomic status and outcomes in heart failure with reduced ejection fraction","volume":"104","author":"Squire","year":"2018","unstructured":"1. 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