{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,7]],"date-time":"2026-11-07T20:24:15Z","timestamp":1794083055080,"version":"4.8.0"},"reference-count":45,"publisher":"Radcliffe Medical Media Ltd","license":[{"start":{"date-parts":[[2025,6,24]],"date-time":"2025-06-24T00:00:00Z","timestamp":1750723200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/legalcode"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur Cardiol"],"abstract":"<jats:p>Background: Over the past decade, significant advancements in percutaneous coronary intervention (PCI) have substantially reduced periprocedural complications. These developments have also made same-day discharge (SDD) following PCI increasingly feasible. This study aims to provide the most up-to-date evidence on the safety of SDD through a synthesis of randomised controlled trial (RCT) results. Methods: We systematically searched the PubMed, Embase, Cochrane Library and ClinicalTrials.gov databases for RCTs comparing the safety of SDD versus overnight stay (ONS) following PCI. Meta-analyses were conducted using a random effects model. Results: A total of 14 RCTs comprising 3,215 patients (1,608 in the SDD group and 1,607 in the ONS group), primarily with chronic coronary syndrome or low-risk acute coronary syndrome, were included. Our meta-analysis demonstrated that SDD is as safe as ONS, as indicated by the comparable risks of adverse events, including major adverse cardiovascular events (pooled RR 0.76; 95% CI [0.46\u20131.27]), major bleeding (pooled RR 1.29; 95%\u00a0CI [0.50\u20133.37]), vascular complications related to the access site (pooled RR 1.06; 95% CI [0.78\u20131.45]), rehospitalisation (pooled RR 1.15; 95% CI [0.79\u20131.68]) and unplanned hospital visits (pooled RR 1.02; 95% CI [0.73\u20131.42]) within 30 days post-PCI. The results remained robust, regardless of access site, timing of discharge or clinical presentation (all p for interaction &gt;0.05). Conclusion: This up-to-date meta-analysis provides strong evidence supporting the safety of SDD compared with ONS after PCI. Further well-designed RCTs involving high-risk acute coronary syndrome patients are warranted to further clarify the safety of the SDD strategy in this population.<\/jats:p>","DOI":"10.15420\/ecr.2025.21","type":"journal-article","created":{"date-parts":[[2025,6,25]],"date-time":"2025-06-25T11:01:15Z","timestamp":1750849275000},"source":"Crossref","is-referenced-by-count":4,"title":["Same-day Discharge Following Percutaneous Coronary Intervention: A Systematic Review and Meta-analysis of Randomised Controlled Trials"],"prefix":"10.15420","volume":"20","author":[{"given":"Ngoc Huy","family":"Nguyen","sequence":"first","affiliation":[{"name":"VNU University of Medicine and Pharmacy, Hanoi, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thanh Ngoc","family":"Le","sequence":"additional","affiliation":[{"name":"VNU University of Medicine and Pharmacy, Hanoi, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1742-3061","authenticated-orcid":false,"given":"Hoai Thi Thu","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Faculty of Medicine, VNU University of Medicine and Pharmacy, Hanoi, Vietnam; Vietnam National Heart Institute, Bach Mai Hospital, Hanoi, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tuan Minh","family":"Pham","sequence":"additional","affiliation":[{"name":"Vietnam National Heart Institute, Bach Mai Hospital, Hanoi, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7487-219X","authenticated-orcid":false,"given":"Dung Viet","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Faculty of Medicine, VNU University of Medicine and Pharmacy, Hanoi, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"6096","published-online":{"date-parts":[[2025,6,24]]},"reference":[{"key":"ref0","doi-asserted-by":"crossref","unstructured":"Inohara T, Kohsaka S, Spertus JA, et al. 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Percutaneous coronary intervention complications and guide catheter size: bigger is not better. JACC Cardiovasc Interv 2009;2:636\u201344. https:\/\/doi.org\/10.1016\/j.jcin.2009.05.012; PMID:\u00a019628187.","DOI":"10.1016\/j.jcin.2009.05.012"},{"key":"ref37","doi-asserted-by":"publisher","unstructured":"Robertson L, Andras A, Colgan F, Jackson R. Vascular closure devices for femoral arterial puncture site haemostasis. Cochrane Database Syst Rev 2016;3:CD009541. https:\/\/doi.org\/10.1002\/14651858.CD009541.pub2; PMID:\u00a026948236.","DOI":"10.1002\/14651858.cd009541.pub2"},{"key":"ref38","doi-asserted-by":"crossref","unstructured":"Gragnano F, Branca M, Frigoli E, et al. Access-site crossover in patients with acute coronary syndrome undergoing invasive management. 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