{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,17]],"date-time":"2025-11-17T05:56:11Z","timestamp":1763358971068,"version":"3.41.2"},"reference-count":26,"publisher":"Radcliffe Medical Media Ltd","license":[{"start":{"date-parts":[[2024,5,9]],"date-time":"2024-05-09T00:00:00Z","timestamp":1715212800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/legalcode"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Interv Cardiol"],"abstract":"<jats:p>Background: Ventricular arrhythmias are a leading cause of sudden death. The objective of this study was to characterise the results of patients with ventricular arrhythmias refractory to standard medical management, undergoing Video-assisted thoracoscopic cardiac sympathetic denervation (VAT-CSD) during 2012\u20132022 in Cali, Colombia. Methods: This was an observational retrospective study, using the Institutional General Thoracic Surgery Database for patient identification and retrospectively reviewing the clinical charts for data description and analysis. Results: Clinical records of 19 patients who underwent VAT-CSD for ventricular arrhythmia were analysed. The patients were predominantly male (73.7%) with an mean age of 62 years. Ischaemic heart disease was the main underlying condition (52.6%); all individuals had a diagnosis of heart failure, with comorbidities such as hypertension (63.1%), acute MI (57.8%) and diabetes (26.3%) also present. The procedure was performed bilaterally in 89.4% of cases and was successful with minimal perioperative complications. Postoperative follow-up showed improvement in symptoms, including a significant reduction in the number of ICD shocks and emergency department visits. Conclusion: VAT-CSD is a viable, safe and palliative therapeutic option for patients with ventricular arrhythmias who have not responded to conventional treatments, achieving a significant decrease in symptoms with low mortality and perioperative complications.<\/jats:p>","DOI":"10.15420\/icr.2023.09","type":"journal-article","created":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T10:03:57Z","timestamp":1715594637000},"source":"Crossref","is-referenced-by-count":3,"title":["Cardiac Sympathetic Denervation as a Treatment for Ventricular Arrhythmias Refractory to Conventional Treatment: A Case Series"],"prefix":"10.15420","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7703-5883","authenticated-orcid":false,"given":"Carolina","family":"\u00c1lvarez-Ortega","sequence":"first","affiliation":[{"name":"Fundaci\u00f3n Valle del Lili, Centro de Investigaciones Cl\u00ednicas, Cali, Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4948-016X","authenticated-orcid":false,"given":"Josu\u00e9 Daniel","family":"G\u00f3mez-Mart\u00ednez","sequence":"additional","affiliation":[{"name":"Fundaci\u00f3n Valle del Lili, Centro de Investigaciones Cl\u00ednicas, Cali, Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6549-0977","authenticated-orcid":false,"given":"Mar\u00eda Alejandra","family":"Cardona-Gallardo","sequence":"additional","affiliation":[{"name":"Universidad Icesi, Facultad de Ciencias de la Salud, Cali, Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8420-5550","authenticated-orcid":false,"given":"Nicol\u00e1s Felipe","family":"Torres-Espa\u00f1a","sequence":"additional","affiliation":[{"name":"Fundaci\u00f3n Valle del Lili, Departamento de Cirug\u00eda, Cali, Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1406-4649","authenticated-orcid":false,"given":"Luis Fernando","family":"Pava-Molano","sequence":"additional","affiliation":[{"name":"Fundaci\u00f3n Valle del Lili, Departamento de Cardiolog\u00eda y Electrofisiolog\u00eda, Cali, Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6199-3358","authenticated-orcid":false,"given":"\u00c1lvaro Ignacio","family":"S\u00e1nchez-Ortiz","sequence":"additional","affiliation":[{"name":"Fundaci\u00f3n Valle del Lili, Departamento de Cirug\u00eda, Divisi\u00f3n de Cirug\u00eda de T\u00f3rax, Cali, Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2307-3670","authenticated-orcid":false,"given":"Mauricio","family":"Vel\u00e1squez-Galvis","sequence":"additional","affiliation":[{"name":"Fundaci\u00f3n Valle del Lili, Departamento de Cirug\u00eda, Divisi\u00f3n de Cirug\u00eda de T\u00f3rax, Cali, Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"6096","published-online":{"date-parts":[[2024,5,9]]},"reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"Nozdrzykowski M, Schroeter T, Sandri M, et al. Concomitant bilateral video-assisted thoracoscopic sympathectomy and minimal-invasive left ventricular assist device implantation. J Heart Lung Transplant 2021;40:707\u20138. https:\/\/doi.org\/10.1016\/j.healun.2021.04.007; PMID:\u00a034030972.","DOI":"10.1016\/j.healun.2021.04.007"},{"key":"ref1","doi-asserted-by":"publisher","unstructured":"Tomaselli GF, Zipes DP. What causes sudden death in heart failure? Circ Res 2004;95:754\u201363. https:\/\/doi.org\/10.1161\/01.RES.0000145047.14691.db; PMID:\u00a015486322.","DOI":"10.1161\/01.res.0000145047.14691.db"},{"key":"ref2","doi-asserted-by":"publisher","unstructured":"Goldberger JJ, Buxton AE, Cain M, et al. Risk stratification for arrhythmic sudden cardiac death: identifying the roadblocks. Circulation 2011;123:2423\u201330. https:\/\/doi.org\/10.1161\/CIRCULATIONAHA.110.959734; PMID:\u00a021632516.","DOI":"10.1161\/circulationaha.110.959734"},{"key":"ref3","unstructured":"Priori SG, Blomstr\u00f6m-Lundqvist C, Mazzanti A, et al. 2015 ESC guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death: the Task Force for the Management of Patients with Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death of the European Society of Cardiology (ESC). Endorsed by: association for European paediatric and congenital cardiology (AEPC). Eur Heart J 2015;36:2793\u2013867. https:\/\/doi.org\/10.1093\/eurheartj\/ehv316; PMID:\u00a026320108."},{"key":"ref4","doi-asserted-by":"publisher","unstructured":"Al-Khatib SM, Stevenson WG, Ackerman MJ, et al. 2017 AHA\/ACC\/HRS guideline for management of patients with ventricular arrhythmias and the prevention of sudden cardiac death. Circulation 2018;138:e272\u2013391. https:\/\/doi.org\/10.1161\/CIR.0000000000000549; PMID:\u00a029084731.","DOI":"10.1161\/cir.0000000000000549"},{"key":"ref5","doi-asserted-by":"publisher","unstructured":"Bigger JT, Fleiss JL, Kleiger R, et al. The relationships among ventricular arrhythmias, left ventricular dysfunction, and mortality in the 2 years after myocardial infarction. Circulation 1984;69:250\u20138. https:\/\/doi.org\/10.1161\/01.cir.69.2.250; PMID:\u00a06690098.","DOI":"10.1161\/01.cir.69.2.250"},{"key":"ref6","doi-asserted-by":"crossref","unstructured":"Kim MC, Kini A, Sharma SK. Refractory angina pectoris: mechanism and therapeutic options. J Am Coll Cardiol 2002;39:923\u201334. https:\/\/doi.org\/10.1016\/s0735-1097(02)01716-3; PMID:\u00a011897431.","DOI":"10.1016\/S0735-1097(02)01716-3"},{"key":"ref7","doi-asserted-by":"publisher","unstructured":"Ambrose JA, Dangas G. Unstable angina: current concepts of pathogenesis and treatment. Arch Intern Med 2000;160:25\u201337. https:\/\/doi.org\/10.1001\/archinte.160.1.25; PMID:\u00a010632302.","DOI":"10.1001\/archinte.160.1.25"},{"key":"ref8","doi-asserted-by":"publisher","unstructured":"Vaseghi M, Barwad P, Malavassi Corrales FJ, et al. Cardiac sympathetic denervation for refractory ventricular arrhythmias. J Am Coll Cardiol 2017;69:3070\u201380. https:\/\/doi.org\/10.1016\/j.jacc.2017.04.035; PMID:\u00a028641796.","DOI":"10.1016\/j.jacc.2017.04.035"},{"key":"ref9","doi-asserted-by":"publisher","unstructured":"Schwartz PJ, Priori SG, Cerrone M, et al. Left cardiac sympathetic denervation in the management of high-risk patients affected by the long-QT syndrome. Circulation 2004;109:1826\u201333. https:\/\/doi.org\/10.1161\/01.CIR.0000125523.14403.1E; PMID:\u00a015051644.","DOI":"10.1161\/01.cir.0000125523.14403.1e"},{"key":"ref10","doi-asserted-by":"publisher","unstructured":"Stritesky M, Dobias M, Demes R, et al. Endoscopic thoracic sympathectomy \u2013 its effect in the treatment of refractory angina pectoris. Interact Cardiovasc Thorac Surg 2006;5:464\u20138. https:\/\/doi.org\/10.1510\/icvts.2005.118976; PMID:\u00a017670622.","DOI":"10.1510\/icvts.2005.118976"},{"key":"ref11","doi-asserted-by":"publisher","unstructured":"Han J, Ackerman MJ, Moir C, et al. Left cardiac sympathetic denervation reduces skin sympathetic nerve activity in patients with long QT syndrome. Heart Rhythm 2020;17:1639\u201345. https:\/\/doi.org\/10.1016\/j.hrthm.2020.03.023; PMID:\u00a032276050.","DOI":"10.1016\/j.hrthm.2020.03.023"},{"key":"ref12","doi-asserted-by":"publisher","unstructured":"Meller ST, Gebhart GF. A critical review of the afferent pathways and the potential chemical mediators involved in cardiac pain. Neuroscience 1992;48:501\u201324. https:\/\/doi.org\/10.1016\/0306-4522(92)90398-l; PMID:\u00a01351270.","DOI":"10.1016\/0306-4522(92)90398-l"},{"key":"ref13","doi-asserted-by":"publisher","unstructured":"Lin Y, Liu H, Yu D, et al. Sympathectomy versus conventional treatment for refractory coronary artery spasm. Coron Artery Dis 2019;30:418\u201324. https:\/\/doi.org\/10.1097\/MCA.0000000000000732; PMID:\u00a030896452.","DOI":"10.1097\/mca.0000000000000732"},{"key":"ref14","doi-asserted-by":"publisher","unstructured":"Vaseghi M, Gima J, Kanaan C, et al. Cardiac sympathetic denervation in patients with refractory ventricular arrhythmias or electrical storm: intermediate and long-term follow-up. Heart Rhythm 2014;11:360\u20136. https:\/\/doi.org\/10.1016\/j.hrthm.2013.11.028; PMID:\u00a024291775.","DOI":"10.1016\/j.hrthm.2013.11.028"},{"key":"ref15","doi-asserted-by":"publisher","unstructured":"T\u00e9llez LJ, Garz\u00f3n JC, Vinck EE, Castellanos JD. Video-assisted thoracoscopic cardiac denervation of refractory ventricular arrhythmias and electrical storms: a single-center series. J Cardiothorac Surg 2019;14:17. https:\/\/doi.org\/10.1186\/s13019-019-0838-6; PMID:\u00a030665431.","DOI":"10.1186\/s13019-019-0838-6"},{"key":"ref16","doi-asserted-by":"publisher","unstructured":"Vel\u00e1squez M, Fern\u00e1ndez L, Leib CS, et al. Cardiac sympathetic denervation for conventional treatment refractory arrhythmias. Arch Cardiol Mex 2019;89:191\u20135. https:\/\/doi.org\/10.24875\/ACME.M19000059; PMID:\u00a031967585.","DOI":"10.24875\/acme.m19000059"},{"key":"ref17","doi-asserted-by":"publisher","unstructured":"Merchanta NN, Onugha OI. VATS sympathectomy for refractory ventricular arrhythmias: is it helpful? J Cardiol Cardiovasc Ther 2017;8:555747. https:\/\/doi.org\/10.19080\/JOCCT.2017.08.555747.","DOI":"10.19080\/jocct.2017.08.555747"},{"key":"ref18","doi-asserted-by":"publisher","unstructured":"Canver CC. Video-assisted thoracoscopic bilateral thoracic sympathectomy: an alternative to pharmaceutical disruption of sympathetic neural activity in patients with heart failure. J Thorac Cardiovasc Surg 2017;153:864. https:\/\/doi.org\/10.1016\/j.jtcvs.2016.11.052; PMID:\u00a028110964.","DOI":"10.1016\/j.jtcvs.2016.11.052"},{"key":"ref19","doi-asserted-by":"publisher","unstructured":"Hofferberth SC, Cecchin F, Loberman D, Fynn-Thompson F. Left thoracoscopic sympathectomy for cardiac denervation in patients with life-threatening ventricular arrhythmias. J Thorac Cardiovasc Surg 2014;147:404\u20139. https:\/\/doi.org\/10.1016\/j.jtcvs.2013.07.064; PMID:\u00a024268954.","DOI":"10.1016\/j.jtcvs.2013.07.064"},{"key":"ref20","doi-asserted-by":"crossref","unstructured":"Kadowaki MH, Levett JM. Sympathectomy in the treatment of angina and arrhythmias. Ann Thorac Surg 1986;41:572\u20138. https:\/\/doi.org\/10.1016\/s0003-4975(10)63050-0; PMID:\u00a03707257.","DOI":"10.1016\/S0003-4975(10)63050-0"},{"key":"ref21","doi-asserted-by":"publisher","unstructured":"Chihara RK, Chan EY, Meisenbach LM, Kim MP. Surgical cardiac sympathetic denervation for ventricular arrhythmias: a systematic review. Methodist Debakey Cardiovasc J 2021;17:24\u201335. https:\/\/doi.org\/10.14797\/QIQG9041; PMID:\u00a034104317.","DOI":"10.14797\/qiqg9041"},{"key":"ref22","doi-asserted-by":"publisher","unstructured":"Richardson T, Lugo R, Saavedra P, et al. Cardiac sympathectomy for the management of ventricular arrhythmias refractory to catheter ablation. Heart Rhythm 2018;15:56\u201362. https:\/\/doi.org\/10.1016\/j.hrthm.2017.09.006; PMID:\u00a028917558.","DOI":"10.1016\/j.hrthm.2017.09.006"},{"key":"ref23","doi-asserted-by":"publisher","unstructured":"Wehman B, Mazzeffi M, Chow R, et al. 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