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Despite this, there has been little progress in the application of these findings to clinical practice. Improved understanding of the sex-specific mechanisms of aortic disease may inform personalized indications for elective repair and thus reduce the morbidity of aortic catastrophe. The objective of this review is to summarize known clinical and biological sex differences in both thoracic and abdominal aortic disease and highlight promising areas for future investigation.<\/jats:p>","DOI":"10.15420\/usc.2022.39","type":"journal-article","created":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T15:04:18Z","timestamp":1696259058000},"source":"Crossref","is-referenced-by-count":9,"title":["Sex and Gender Differences in Aortic Disease"],"prefix":"10.15420","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3486-8337","authenticated-orcid":false,"given":"Lauren V","family":"Huckaby","sequence":"first","affiliation":[{"name":"Division of Cardiac Surgery, Emory University, Atlanta, GA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2290-1729","authenticated-orcid":false,"given":"Bradley G","family":"Leshnower","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery, Emory University, Atlanta, GA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"6096","published-online":{"date-parts":[[2023,9,28]]},"reference":[{"key":"ref0","unstructured":"Centers for Disease Control and Prevention. 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