{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T02:54:21Z","timestamp":1793415261244,"version":"4.5.0"},"reference-count":40,"publisher":"Universidad Nacional de Colombia","issue":"4","license":[{"start":{"date-parts":[[2017,7,1]],"date-time":"2017-07-01T00:00:00Z","timestamp":1498867200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. salud p\u00fablica"],"abstract":"<jats:p>Diferentes especies de roedores son potenciales transmisores de m\u00faltiples agentes zoon\u00f3ticos como Leptospira spp., espiroqueta causante de la Leptospirosis, que es una enfermedad infecciosa que tiene un impacto negativo en la porcicultura debido a que genera grandes p\u00e9rdidas productivas, reproductivas y econ\u00f3micas.En las granjas porcinas, las especies de roedores m\u00e1s comunes son el rat\u00f3n dom\u00e9stico (Mus musculus), la rata parda (Rattus norvegicus) y la rata negra (Rattus rattus), que act\u00faan como hu\u00e9spedes de mantenimiento de diferentes serovares de Leptospira spp., contaminando con orina el ambiente, los alimentos y el agua, poniendo en riesgo la salud humana y animal.Por esta raz\u00f3n, el objetivo de este art\u00edculo es describir el papel de los roedores en la transmisi\u00f3n de Leptospira en granjas porcinas. Para esto, se realiz\u00f3 una b\u00fasqueda bibliogr\u00e1fica en diferentes bases de datos como Science Direct, Scopus, Redalyc, PubMed y SciELO. Los resultados de la revisi\u00f3n de literatura, demuestran que son escasos los estudios que reportan la importancia de los roedores en la transmisi\u00f3n de Leptospira en granjas porcinas. La presentaci\u00f3n de la enfermedad depende en gran parte de la presencia, el contacto y el control de roedores en las granjas, aunque tambi\u00e9n se deben tener en cuenta factores ambientales, de supervivencia del agente y las medidas de higiene, entre otros.\u00a0\u00a0\u00a0<\/jats:p>","DOI":"10.15446\/rsap.v19n4.41626","type":"journal-article","created":{"date-parts":[[2018,4,9]],"date-time":"2018-04-09T21:18:37Z","timestamp":1523308717000},"page":"555-561","source":"Crossref","is-referenced-by-count":9,"title":["Papel de los roedores en la transmisi\u00f3n de Leptospira spp. en granjas porcinas"],"prefix":"10.15446","volume":"19","author":[{"given":"Catalina","family":"Ospina-Pinto","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuel","family":"Rincon-Pardo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diego","family":"Soler-Tovar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia","family":"Hern\u00e1ndez-Rodr\u00edguez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"6146","published-online":{"date-parts":[[2017,7,1]]},"reference":[{"key":"ref1","unstructured":"Stuart AM, Prescott CV, MacIntyre S, Sethar A, Neuman BW, McCarthy ND, Wimalarathna H, Maiden MCJ. The role of rodents as carriers of disease on UK farms: a preliminary investigation. 8th European Vertebrate Pest Management Conference, Julius-K\u00fchn-Archiv. 2011; 432: 198-199."},{"key":"ref2","unstructured":"Jardine CM. Surveillance of disease agents of public health and agricultural significance in wildlife living on farms in Ontario. Wrap-up meeting of the 2008-2013 Animal Health Strategic Investment, University of Guelph, Canada: 1-6."},{"key":"ref3","doi-asserted-by":"crossref","unstructured":"Adler B, De la Pe\u00f1a A. Leptospira and Leptospirosis. Veterinary Microbiology. 2010; 140: 287-296.","DOI":"10.1016\/j.vetmic.2009.03.012"},{"key":"ref4","unstructured":"Tesic M, Zugic G, Kljajic R, Blagojevic M. Leptospirosis on a pig farm: health and economic significance and creation of eradication program. Proceedings of the 10th International Symposium on Veterinary Epidemiology and Economics 2003: 1-3."},{"key":"ref5","doi-asserted-by":"crossref","unstructured":"Hill W, Brown J. Zoonoses of Rabbits and Rodents. Veterinary Clinics of North America: Exotic Animal Practice 2011; 14: 519-531.","DOI":"10.1016\/j.cvex.2011.05.009"},{"key":"ref6","doi-asserted-by":"crossref","unstructured":"Gort\u00e1zar C, Ferroglio E, H\u00f6fle U, Fr\u00f6lich K, Vicente J. Diseases shared between wildlife and livestock: a European perspective. European Journal of Wildlife Research. 2007; 53: 241-256.","DOI":"10.1007\/s10344-007-0098-y"},{"key":"ref7","doi-asserted-by":"crossref","unstructured":"Orrego A, Giraldo G, Boh\u00f3rquez A, Escobar J, Quiceno J, R\u00edos B, Santaf\u00e9 M, Hurtado J. Aproximaci\u00f3n a la prevalencia serol\u00f3gica real de la leptospirosis en porcinos-cr\u00eda. Rev. Corpoica2001; 3 (2): 11-16.","DOI":"10.21930\/rcta.vol3_num2_art:182"},{"key":"ref8","doi-asserted-by":"crossref","unstructured":"Hern\u00e1ndez-Rodr\u00edguez P, D\u00edaz C, Dalmau E, Quintero G. A comparison between Polymerase Chain Reaction (PCR) and traditional techniques for diagnosis of leptospirosis in bovines. Journal of Microbiological Methods 2011; 84(1): 1-7.","DOI":"10.1016\/j.mimet.2010.10.021"},{"key":"ref9","doi-asserted-by":"crossref","unstructured":"Picardeau M. Diagnosis and epidemiology of leptospirosis. M\u00e9decine et maladies infectieuses 2013; 43: 1-9.","DOI":"10.1016\/j.medmal.2012.11.005"},{"key":"ref10","doi-asserted-by":"crossref","unstructured":"Levett P. Leptospirosis. Clinical Microbiology Reviews 2001; 14(2): 296-326.","DOI":"10.1128\/CMR.14.2.296-326.2001"},{"key":"ref11","unstructured":"Jorge S, Hartleben C, Seixas F, Coimbra M, Stark C, Larrondo A, Amaral M, Albano A, Minello L, Dellagostin O, Brod C. Leptospira borgpetersenii from free-living white-eared opossum"},{"key":"ref12","doi-asserted-by":"crossref","unstructured":"(Didelphis albiventris): First isolation in Brazil. Acta Tropica 2012; 124: 147-151.","DOI":"10.1016\/j.actatropica.2012.07.009"},{"key":"ref13","unstructured":"Instituto Nacional de Salud-INS. Protocolo de Vigilancia y Control de Leptospirosis, Grupo Enfermedades Transmisibles,Equipo Funcional Zoonosis, Vigilancia y Control en Salud"},{"key":"ref14","unstructured":"P\u00fablica 2011: 1-21."},{"key":"ref15","doi-asserted-by":"crossref","unstructured":"Jackson P, Cockcroft P. Polysystemic diseases. En: Jackson P, Cockcroft P. Handbook of Pig Medicine. Primera edici\u00f3n, Iowa, USA: Editorial Saunders Elsevier Health Sciences; 2007.","DOI":"10.1016\/B978-0-7020-2828-1.50015-3"},{"key":"ref16","unstructured":"Feraud D, Abeledo M. Primer reporte en Cuba de Leptospira interrogans serovar Tarassovi y caracterizaci\u00f3n cl\u00ednica epizootiologica en focos de Leptospirosis porcina. Revista Electr\u00f3nica de Veterinaria REDVET 2005; 6(4): 1-35."},{"key":"ref17","unstructured":"Ellis WA. Leptospirosis. En: Zimmerman J, Karriker L, Ramirez A, Schwartz K, Stevenson G. Diseases of Swine. D\u00e9cima edici\u00f3n. USA: Wiley-Blackwell; 2012."},{"key":"ref18","unstructured":"C\u00e9spedes M. Leptospirosis: Enfermedad Zoon\u00f3tica Emergente. Rev. Peruana de Medicina Experimental y Salud P\u00fablica 2005; 22(4): 290-307."},{"key":"ref19","doi-asserted-by":"crossref","unstructured":"Athanazio D, Silva E, Santos C, Rocha G, Vannier-Santos M, McBride A., Ko A, Reis M. Rattus norvegicus as a model for persistent renal colonization by pathogenic Leptospira interrogans. Acta Tropica 2008; 105: 176-180.","DOI":"10.1016\/j.actatropica.2007.10.012"},{"key":"ref20","doi-asserted-by":"crossref","unstructured":"Tucunduva M, Calderwood M, Athanazio D, McBride A, Hartskeerl R, Pereira M, Ko A, Reis M. Carriage of Leptospira interrogans among domestic rats from an urban setting highly endemic for leptospirosis in Brazil. Acta Tropica 2008; 108: 1-5.","DOI":"10.1016\/j.actatropica.2008.07.005"},{"key":"ref21","doi-asserted-by":"crossref","unstructured":"Tucunduva M, Athanazio D, Goncalves E, Silva E, Reis M, Ko A. Morphological Alterations in the Kidney of Rats with Natural and Experimental Leptospira Infection. Journal of Comparative Pathology 2007; 137: 231-238.","DOI":"10.1016\/j.jcpa.2007.08.001"},{"key":"ref22","doi-asserted-by":"crossref","unstructured":"Desvars A, Michault A, Chiroleu F. Influence of risk factors on renal leptospiral load in naturally infected wild black rats. Acta Tropica 2013; 125: 258-261.","DOI":"10.1016\/j.actatropica.2012.11.011"},{"key":"ref23","doi-asserted-by":"crossref","unstructured":"Backhans A, Fellstrom C. Rodents on pig and chicken farms - a potential threat to human and animal health. Infection Ecology and Epidemiology 2012; 2: 1-9.","DOI":"10.3402\/iee.v2i0.17093"},{"key":"ref24","unstructured":"Ricci M, Pad\u00edn S. Roedores transmisores de enfermedades: medidas de prevenci\u00f3n y control. Gu\u00eda de estudios universitarios. Facultad de Ciencias Agrarias y Forestales. Universidad de La Plata, Argentina 2001: 1-17."},{"key":"ref25","unstructured":"Sep\u00falveda A, Dimas J, Preciado F. La rata y el perro, importantes vectores de la leptospirosis en explotaciones pecuarias de Cd. Guzm\u00e1n, Jalisco. Rev. Cubana de Medicina Tropical 2002; 54: 21-23."},{"key":"ref26","unstructured":"Ellis WA. Leptospirosis. En: Straw B, Zimmerman J, D\u2019Allaire S, Taylor D. Diseases of Swine. Novena edici\u00f3n. USA: Blackwell Publishing; 2006."},{"key":"ref27","unstructured":"Morales R, Bravo D, Moreno D, G\u00f3ngora A, Ocampo A. Asociaci\u00f3n serol\u00f3gica de la infecci\u00f3n por leptospira en humanos, porcinos y roedores en una granja de Villavicencio-Colombia. Rev. Orinoquia 2007; 11(2): 73-80."},{"key":"ref28","doi-asserted-by":"crossref","unstructured":"Webster JP, Ellis WA, Macdonald DW. Prevalence of Leptospira spp. in wild brown rats (Rattus norvegicus) on UK farms. Epidemiology and Infection 1995; 114: 195-201.","DOI":"10.1017\/S0950268800052043"},{"key":"ref29","unstructured":"Agudelo-Fl\u00f3rez P, Arango J, Merizalde E, Londo\u00f1o A, Quiroz V, Rodas J. Evidencia serol\u00f3gica de circulaci\u00f3n de Leptospira spp en Rattus norvegicus naturalmente expuestos en una zona urbana colombiana. Rev. Salud P\u00fablica (Bogot\u00e1). 2010; 12(6): 990-999."},{"key":"ref30","unstructured":"Arango J, Cittadino E, Agostini A, Dorta G, \u00c1lvarez C, Colusi M, Koval A, Cabrera A, Kravetz F. Prevalencia de leptospiras en Rattus rattus y Rattus norvegicus en el Gran Buenos Aires, Argentina. Ecolog\u00eda Austral 2001; 11: 25-30."},{"key":"ref31","unstructured":"Marder G, Ruiz RM, R\u00edos LM, Zorzo L, Merino D. Detecci\u00f3n de leptospiras en ri\u00f1on de roedores de la ciudad de Corrientes: estudio preliminar, Universidad Nacional del Nordeste. Comunicaciones Cient\u00edficas y Tecnol\u00f3gicas 2006; 5 (008): 1-4."},{"key":"ref32","doi-asserted-by":"crossref","unstructured":"Giraldo G, Orrego A, Betancurth A. Los roedores como reservorios de Leptospiras en planteles porcinos de la zona central cafetera de Colombia. Archivos de Medicina Veterinaria 2002; 34(1): 69-78.","DOI":"10.4067\/S0301-732X2002000100007"},{"key":"ref33","unstructured":"Scialfa E, Bolpe J, Bard\u00f3n JC, Ridao G, Gentile J, Gallicchio O. Isolation of Leptospira interrogans from suburban rats in Tandil, Buenos Aires, Argentina. Rev. Argentina de Microbiolog\u00eda 2010; 42(2): 126-128."},{"key":"ref34","unstructured":"Wangroongsarb P, Petkanchanapong W, Yasaeng S, Imvithaya A, Naigowit P. Survey of Leptospirosis among Rodents in Epidemic Areas of Thailand. Journal of Tropical Medicine and Parasitology 2002; 25(2): 55-58."},{"key":"ref35","doi-asserted-by":"crossref","unstructured":"Himsworth CG, Bidulka J, Parsons KL, Feng AYT, Tang P, Jardine CM, Kerr T, Mak S, Robinson J, Patrick DM. Ecology of Leptospira interrogans in Norway Rats (Rattus norvegicus) in an Inner-City Neighborhood of Vancouver, Canada. PLOS Neglected Tropical Diseases 2013; 7(6): 1-9.","DOI":"10.1371\/journal.pntd.0002270"},{"key":"ref36","doi-asserted-by":"crossref","unstructured":"Paiva-Cardoso M, Arent Z, Gilmore C, Hartskeerl R, Ellis WA. Altodouro, a new Leptospira serovar of the Pomona serogroup isolated from rodents in northern Portugal. Infection, Genetics and Evolution 2013; 13: 211-217.","DOI":"10.1016\/j.meegid.2012.09.013"},{"key":"ref37","unstructured":"Tobin M, Fall M. Pest Control: Rodents. USDA National Wildlife Research Center, Staff Publications 2004; 67: 1-20."},{"key":"ref38","unstructured":"See T. Control de roedores. Bolet\u00edn Bioseguridad 2004; 4(18): 1-6."},{"key":"ref39","unstructured":"Pierce R. Controlling rats. University of Missouri Office of Extension 2012: 1-6."},{"key":"ref40","unstructured":"Vercauteren K, Hygnstrom S, Timm R, Corrigan R, Beller J, Bitney L, Brumm M, Meyer D, Virchow D, Wills R. Development of a Model to Assess Rodent Control in Swine Facilities. Human Conflicts with Wildlife: Economic Considerations 2000; 7: 59-64."}],"container-title":["Revista de Salud P\u00fablica"],"original-title":[],"link":[{"URL":"https:\/\/revistas.unal.edu.co\/index.php\/revsaludpublica\/article\/viewFile\/41626\/65594","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/revistas.unal.edu.co\/index.php\/revsaludpublica\/article\/viewFile\/41626\/65594","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,12]],"date-time":"2024-03-12T18:31:59Z","timestamp":1710268319000},"score":1,"resource":{"primary":{"URL":"https:\/\/revistas.unal.edu.co\/index.php\/revsaludpublica\/article\/view\/41626"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,7,1]]},"references-count":40,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2017,7,1]]}},"URL":"https:\/\/doi.org\/10.15446\/rsap.v19n4.41626","relation":{},"ISSN":["2539-3596","0124-0064"],"issn-type":[{"value":"2539-3596","type":"electronic"},{"value":"0124-0064","type":"print"}],"subject":[],"published":{"date-parts":[[2017,7,1]]}}}