{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T05:07:09Z","timestamp":1747199229867,"version":"3.40.5"},"reference-count":6,"publisher":"Universidad Nacional de Colombia","issue":"2","license":[{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. salud p\u00fablica"],"abstract":"<jats:p>\n\n\n\n\n\nSe presenta el caso de un paciente masculino de 46 a\u00f1os. Este ingres\u00f3 al servicio de urgencias con un cuadro cl\u00ednico de una hora de evoluci\u00f3n caracterizado por dolor tor\u00e1cico opresivo de intensidad 10\/10 seg\u00fan la escala an\u00e1loga del dolor. Despu\u00e9s de la valoraci\u00f3n y frente a los hallazgos electrocardiogr\u00e1ficos y de laboratorio, se diagnostic\u00f3 al paciente con infarto agudo de miocardio con elevacio\u0301n del ST, adem\u00e1s, se sospech\u00f3 de disecci\u00f3n a\u00f3rtica y de una emergencia hipertensiva a \u00f3rgano blanco coraz\u00f3n debido al intenso dolor precordial y las cifras tensionales de 230\/120 mmHg. Dentro del esquema terap\u00e9utico, se indicaron 3 mg de morfina intravenosa diluida en 10 ml de soluci\u00f3n salina 0,9%. Despu\u00e9s de la administraci\u00f3n, el paciente presento\u0301 sospecha de hipersensibilidad. Por ende, se realiz\u00f3 una evaluaci\u00f3n de sospecha de evento adverso utilizando el algoritmo de Naranjo y se estableci\u00f3 que los efectos de morfina eran plausibles (categor\u00eda probable).\n\n\n\n\n\n<\/jats:p>","DOI":"10.15446\/rsap.v25n2.103211","type":"journal-article","created":{"date-parts":[[2023,6,6]],"date-time":"2023-06-06T16:50:06Z","timestamp":1686070206000},"page":"1-4","source":"Crossref","is-referenced-by-count":0,"title":["Sospecha de hipersensibilidad probablemente relacionada con el uso de morfina: reporte de caso"],"prefix":"10.15446","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1351-7514","authenticated-orcid":false,"given":"Roxana","family":"De las Salas","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5791-5234","authenticated-orcid":false,"given":"Gregorio","family":"D\u00edaz-Morales","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5092-7029","authenticated-orcid":false,"given":"Juana","family":"Borja-Gonz\u00e1lez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5092-7029","authenticated-orcid":false,"given":"Kevin Andr\u00e9s","family":"Orta Visbal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7105-0035","authenticated-orcid":false,"given":"Laura","family":"Alvarado Guerra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6417-809X","authenticated-orcid":false,"given":"Donaldo","family":"De la Hoz Santander","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"6146","published-online":{"date-parts":[[2023,3,1]]},"reference":[{"key":"2044505","unstructured":"Centro de Informaci\u00f3n de Medicamentos (CIMA). Ficha t\u00e9cnica morfina [Internet]. Agencia Espa\u00f1ola de Medicamentos y Productos Sanitarios. 2021 [citado 10 de Agosto de 2022]. Disponible en: https:\/\/shorturl.at\/fPR48."},{"key":"2044506","doi-asserted-by":"crossref","unstructured":"Demoly P, Adkinson NF, Brockow K, Castells M, Chiriac AM, Greenberger PA, et al. International Consensus on drug allergy. Allergy. 2014; 69(4):420-437. https:\/\/doi.org\/10.1111\/all.12350","DOI":"10.1111\/all.12350"},{"key":"2044507","doi-asserted-by":"crossref","unstructured":"Task Force Members European Society of Cardiology (ESC). ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation: The Task Force on the management of ST -segment elevation acute myocardial infarction of the European Society of Cardiology (ESC). European Heart Journal. 2012; 33(20):2569\u20132619. https:\/\/doi.org\/10.1093\/eurheartj\/ehs215","DOI":"10.1093\/eurheartj\/ehs215"},{"key":"2044508","unstructured":"World Health Organization (WHO). Vigiaccess: Morphine [Internet]. Uppsala Monitoring Centre (UMC). 2022 [citado 10 de Agosto de 2022]. Disponible en: https:\/\/shorturl.at\/FJRTZ."},{"key":"2044509","unstructured":"Strauss J, Greeff OB. Excipient-related adverse drug reactions: A clinical approach. Current Allergy and Clinical Immunology. 2015; 28(1):24-27. https:\/\/shorturl.at\/entUX."},{"key":"2044510","doi-asserted-by":"crossref","unstructured":"Park BK, Naisbitt DJ, Demoly P. Drug hypersensitivity. En: Holgate S, Church M, Broide D, Martinez F, editores. Allergy. New York: Elsevier; 2012. p. 321\u2013330.","DOI":"10.1016\/B978-0-7234-3658-4.00020-2"}],"container-title":["Revista de Salud P\u00fablica"],"original-title":[],"link":[{"URL":"https:\/\/revistas.unal.edu.co\/index.php\/revsaludpublica\/article\/download\/103211\/88496","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/revistas.unal.edu.co\/index.php\/revsaludpublica\/article\/download\/103211\/88496","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,6]],"date-time":"2023-06-06T16:50:35Z","timestamp":1686070235000},"score":1,"resource":{"primary":{"URL":"https:\/\/revistas.unal.edu.co\/index.php\/revsaludpublica\/article\/view\/103211"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,1]]},"references-count":6,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2023,1,1]]}},"URL":"https:\/\/doi.org\/10.15446\/rsap.v25n2.103211","relation":{},"ISSN":["2539-3596","0124-0064"],"issn-type":[{"type":"electronic","value":"2539-3596"},{"type":"print","value":"0124-0064"}],"subject":[],"published":{"date-parts":[[2023,3,1]]}}}