{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T21:27:16Z","timestamp":1790717236626,"version":"4.1.0"},"reference-count":0,"publisher":"Universidad de Costa Rica","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["RBT"],"abstract":"<jats:p>&lt;p&gt;The increased bacterial resistance to antibiotics has caused global concern, prompting the search for new compounds. Because of their abundance and diversity, marine phytoplankton are an important potential source of such compounds. Research on dinoflagellates has led to the discovery of inhibitors of bacterial growth. The marine dinoflagellate &lt;em&gt;Lingulodinium polyedrum&lt;\/em&gt; blooms in different regions of the world, including Mexico, and is also known to regulate the growth of other species in coastal waters. Here, we investigate the taxonomy of this dinoflagellate and characterize the ability of its extracts to inhibit the growth of two bacteria of medical importance (&lt;em&gt;Vibrio&lt;\/em&gt; &lt;em&gt;vulnificus&lt;\/em&gt; and &lt;em&gt;Staphylococcus&lt;\/em&gt; &lt;em&gt;aureus&lt;\/em&gt;) on agar culture plates. Taxonomic characterization was performed by PCR and gene amplification of ITS, and confirmed that the species isolated off the Pacific coast of Mexico was &lt;em&gt;L.&lt;\/em&gt; &lt;em&gt;polyedrum&lt;\/em&gt;. To prove the inhibitory effect of &lt;em&gt;L. polyedrum&lt;\/em&gt; extracts, cultures were harvested by centrifugation. Pellets from three cellular abundances were extracted with water, methanol, hexane and chloroform. The experiments on &lt;em&gt;V. vulnificus&lt;\/em&gt; showed a high growth inhibition for the four extracts, ranging from 77 to 98%. Surprisingly, the growth inhibition was lower when the extracts originated from a higher &lt;em&gt;L. polyedrum&lt;\/em&gt; cell abundance, ranging from 0 to 34%. For &lt;em&gt;S. aureus&lt;\/em&gt;, the growth inhibition was also high, but not statistically different for all extracts and cell abundances, ranging from 62 to 99%. This shows promise for future pharmacological applications. Our Mexican strain of &lt;em&gt;L. polyedrum&lt;\/em&gt; did not produce any detectable yessotoxins.&lt;\/p&gt;<\/jats:p>","DOI":"10.15517\/rbt.v64i2.19320","type":"journal-article","created":{"date-parts":[[2016,6,7]],"date-time":"2016-06-07T20:33:49Z","timestamp":1465331629000},"page":"805","source":"Crossref","is-referenced-by-count":10,"title":["The inhibitory effect of a non-yessotoxin-producing dinoflagellate, Lingulodinium polyedrum (Stein) Dodge, towards Vibrio vulnificus and Staphylococcus aureus"],"prefix":"10.15517","volume":"64","author":[{"given":"Sonia","family":"Quijano-Scheggia","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"6251","published-online":{"date-parts":[[2016,5,13]]},"container-title":["Revista de Biolog\u00eda Tropical"],"original-title":[],"link":[{"URL":"http:\/\/revistas.ucr.ac.cr\/index.php\/rbt\/article\/viewFile\/19320\/24575","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/revistas.ucr.ac.cr\/index.php\/rbt\/article\/viewFile\/19320\/24576","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2016,6,7]],"date-time":"2016-06-07T20:33:55Z","timestamp":1465331635000},"score":1,"resource":{"primary":{"URL":"http:\/\/revistas.ucr.ac.cr\/index.php\/rbt\/article\/view\/19320"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,5,13]]},"references-count":0,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2016,5,13]]}},"URL":"https:\/\/doi.org\/10.15517\/rbt.v64i2.19320","relation":{},"ISSN":["2215-2075","0034-7744"],"issn-type":[{"value":"2215-2075","type":"electronic"},{"value":"0034-7744","type":"print"}],"subject":[],"published":{"date-parts":[[2016,5,13]]}}}