{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,11]],"date-time":"2025-12-11T20:58:11Z","timestamp":1765486691097},"reference-count":0,"publisher":"Medical Communications Sp. z.o.o.","issue":"87","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Ultrason"],"published-print":{"date-parts":[[2021,11,29]]},"abstract":"<jats:p>Background: Twinkle artifact, also known as color Doppler comet-tail artifact,\n            occurs behind very strong, granular, and irregular reflecting interfaces such as\n            crystals, stones, or calcification. This is visualized as a random mixture of red and\n            blue pixels in the high-frequency shift spectrum located deep to the interface. Study\n            results have suggested that the sonographic twinkling artifact may aid in the detection\n            of renal stones with a variety of reference standard imaging modalities, including\n            abdominal radiography, excretory urography, gray-scale sonography, and CT. Material and\n            methods: Our retrospective observational study included children who had undergone\n            abdomen\/renal ultrasound for kidneys stones in our radiology department between 2013 and\n            2019. Presence of the twinkle artifact, and stone numbers and sizes were documented. CT\n            examinations done &lt;3 months prior to or after US were retrospectively assessed to\n            confirm the presence of kidney stones as a reference standard. Results: Thirty-three\n            abdominal renal US scans of 33 patients (21 males, 12 females) fulfilled the entry\n            criteria. The interval between the US and CT was &lt;3 months for all patients. The\n            median overall age of the patients was 4 years (IQR: 3.125, range: 1\u2013 165 months), The\n            median number of days between the US and CT was 13 (IQR: 26, range: 0\u201381 days). US\n            detected 33 hyperechoic foci suspected to be stones; 26 were confirmed as true positive\n            (i.e. showed the twinkle artifact and were seen in CT), 4 were false positive (showed\n            the twinkle artifact but were not seen in CT), and 3 were false negative (did not show\n            the twinkle artifact but were seen in CT). The overall median stone size was 2 mm in the\n            right kidney, and 5 mm in the left kidney (IQR: 6,11 mm), respectively. Twinkle artifact\n            sensitivity was found to be 89.7% (95% CI 39.574%\u201390%). The twinkle artifact was\n            assessed in all true-positive stones, determining a relatively high PPV of 26\/29 (86.7%)\n            for the twinkle artifact. The twinkle artifact was not dependent on stone size.\n            Specificity for the twinkle artifact could not be calculated due to a lack of true\n            negatives. Conclusion: The twinkle artifact is a sensitive US tool for detecting\n            pediatric kidney and ureter stones, but with a small risk of false positive\n            findings.<\/jats:p>","DOI":"10.15557\/jou.2021.0048","type":"journal-article","created":{"date-parts":[[2021,12,9]],"date-time":"2021-12-09T11:38:54Z","timestamp":1639049934000},"page":"282-285","source":"Crossref","is-referenced-by-count":4,"title":["Twinkle artifact in renal ultrasound, is it a solid point for the diagnosis of\n            renal stone in children?"],"prefix":"10.15557","volume":"21","author":[{"given":"Moath","family":"AlSaiady","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmad","family":"Alqatie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Musab","family":"Almushayqih","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"6250","published-online":{"date-parts":[[2021,11,29]]},"container-title":["Journal of Ultrasonography"],"original-title":[],"link":[{"URL":"http:\/\/www.jultrason.pl\/artykul.php?a=990","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,9]],"date-time":"2021-12-09T11:39:11Z","timestamp":1639049951000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.jultrason.pl\/index.php\/issues\/volume-21-no-87\/twinkle-artifact-in-renal-ultrasound-is-it-a-solid-point-for-the-diagnosis-of-renal-stone-in-children"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,29]]},"references-count":0,"journal-issue":{"issue":"87","published-online":{"date-parts":[[2021,11,29]]},"published-print":{"date-parts":[[2021,11,29]]}},"URL":"https:\/\/doi.org\/10.15557\/jou.2021.0048","relation":{},"ISSN":["2084-8404","2451-070X"],"issn-type":[{"value":"2084-8404","type":"print"},{"value":"2451-070X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,11,29]]}}}