{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T18:06:19Z","timestamp":1793642779407,"version":"4.5.1"},"reference-count":0,"publisher":"Medical Communications Sp. z.o.o.","issue":"100","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Ultrason"],"published-print":{"date-parts":[[2025,1,20]]},"abstract":"<jats:p>Aim: To investigate the changes in liver stiffness and immune-inflammatory markers associated with\nobesity and the degree of hepatic steatosis in obese children and adolescents. Methods: A total of 76\nobese children and adolescents aged 6\u201318 years, with body mass index percentiles &gt;95th, were included\nin the study. Patients with metabolic syndrome, diabetes mellitus, and chronic liver disease were excluded.\nA control group of 44 patients of healthy and normal-weight children was included. Laboratory values from\nthe past month were analyzed using patient records. Shear wave elastography and ultrasound examinations\nwere performed on a single device by the same experienced radiologist. Results: The systemic immuneinflammation\nindex and pan-immune inflammation values were significantly higher in obese patients with\nhepatic steatosis compared to obese patients without hepatic steatosis (p &lt;0.001). Liver stiffness values\nwere significantly higher in steatotic patients compared to nonsteatotic patients (p &lt;0.001). A significant\ndifference was observed between hepatic steatosis grades in terms of immune-inflammation index and\npan-immune inflammation value values (p &lt;0.001). There was a strong, positive, statistically significant\ncorrelation between liver stiffness and immune-inflammation index and pan-immune inflammation value\n(p &lt;0.05). Conclusions: Immune-inflammatory biomarkers and shear wave elastography may provide\nvaluable insights into the diagnosis and follow-up of inflammation and fibrosis in the evaluation of hepatic\nsteatosis in obese children and adolescents.<\/jats:p>","DOI":"10.15557\/jou.2025.0001","type":"journal-article","created":{"date-parts":[[2025,1,21]],"date-time":"2025-01-21T09:50:51Z","timestamp":1737453051000},"source":"Crossref","is-referenced-by-count":8,"title":["Evaluation of hepatic steatosis in obese children and adolescents using immune-inflammatory markers and shear wave elastography"],"prefix":"10.15557","volume":"25","author":[{"name":"Radiology Department, Malatya Turgut \u00d6zal University, Faculty of Medicine, Turkey","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0232-1284","authenticated-orcid":false,"given":"Mehmet","family":"Ak\u00e7i\u00e7ek","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9342-0244","authenticated-orcid":false,"given":"Nurullah","family":"Da\u011f","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Radiology, Malatya Training and Research Hospital, Turkey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"6250","published-online":{"date-parts":[[2025,1,21]]},"container-title":["Journal of Ultrasonography"],"original-title":[],"link":[{"URL":"https:\/\/jultrason.pl\/artykul.php?a=1264","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,21]],"date-time":"2025-01-21T09:50:53Z","timestamp":1737453053000},"score":1,"resource":{"primary":{"URL":"https:\/\/jultrason.pl\/index.php\/issues\/volume-25-no-100-open-issue\/evaluation-of-hepatic-steatosis-in-obese-children-and-adolescents-using-immune-inflammatory-markers-and-shear-wave-elastography"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,20]]},"references-count":0,"journal-issue":{"issue":"100","published-online":{"date-parts":[[2025,1,21]]},"published-print":{"date-parts":[[2025,1,20]]}},"URL":"https:\/\/doi.org\/10.15557\/jou.2025.0001","relation":{},"ISSN":["2084-8404","2451-070X"],"issn-type":[{"value":"2084-8404","type":"print"},{"value":"2451-070X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,20]]}}}