{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,29]],"date-time":"2025-12-29T15:02:34Z","timestamp":1767020554340,"version":"3.48.0"},"reference-count":30,"publisher":"Medical Communications Sp. z.o.o.","issue":"101","license":[{"start":{"date-parts":[[2025,6,30]],"date-time":"2025-06-30T00:00:00Z","timestamp":1751241600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Ultrason"],"abstract":"<jats:p>Aim of the study: Skin ultrasonography and elastography provide information on superficial tissue anatomy\nand elasticity. Floppy eyelid syndrome is characterized by eyelid hyperlaxity and is associated with\nseveral ophthalmic and systemic conditions, such as obstructive sleep apnea. This study evaluates the diagnostic\nrole of ultrasonography and elastography in floppy eyelid syndrome. Methods: This is a prospective\ncase-control study. Patients were recruited from the Oculoplastic Service of the Department of Ophthalmology\nat the University Hospital of Heraklion, Crete, Greece. The diagnosis of floppy eyelid syndrome\nwas based on the eversion of the upper eyelid upon unassisted digital traction. Cataract surgery candidates\nwithout floppy eyelid syndrome were consecutively recruited as controls. Patients with a history of previous\neyelid pathology or surgery were excluded. Ultrasound examination was performed using high-frequency\nlinear probes (GE E9) for B-mode imaging and shear wave and strain elastography. Upper airway measurements\nincluded tongue thickness and upper airway length. Clinical and demographic findings were\nrecorded. Results: Twenty-eight patients were included (14 with floppy eyelid syndrome, 14 controls). Orbicularis\nmuscle elasticity in kPa was significantly higher in the floppy eyelid syndrome group, compared\nwith controls (independent samples t-test score 2.64, p = 0.04). Tongue thickness and upper airway length\nwere also significantly correlated with several eyelid B-mode and elastography parameters in patients with\nfloppy eyelid syndrome, including subcutaneous fat and orbicularis muscle thickness and elasticity. Conclusions:\nFindings from this feasibility study imply that ultrasound and elastography parameters may be\nused in the evaluation of floppy eyelid syndrome and support an association between eyelid elasticity and\nupper airway anatomical parameters in this condition.<\/jats:p>","DOI":"10.15557\/jou.2025.0019","type":"journal-article","created":{"date-parts":[[2025,12,29]],"date-time":"2025-12-29T14:57:48Z","timestamp":1767020268000},"source":"Crossref","is-referenced-by-count":0,"title":["Ultrasound imaging in floppy eyelid syndrome: anatomical and clinical considerations"],"prefix":"10.15557","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6251-4283","authenticated-orcid":false,"given":"Vasilios","family":"Batis","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, School of Medicine, University of Crete, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1251-3965","authenticated-orcid":false,"given":"Efstathios","family":"Detorakis","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, School of Medicine, University of Crete, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0984-2584","authenticated-orcid":false,"given":"Sophia","family":"Schiza","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine and Sleep Disorders Unit, School of Medicine, University of Crete, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1208-1990","authenticated-orcid":false,"given":"Emmanuel","family":"Prokopakis","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology and Laboratory of Translational Otorhinolaryngology Research, School of Medicine, University of Crete, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2197-2530","authenticated-orcid":false,"given":"Konstantinos","family":"Krasagakis","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Medical School, University of Crete, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3629-3277","authenticated-orcid":false,"given":"Elena","family":"Drako\u0144ski","sequence":"additional","affiliation":[{"name":"Department of Anatomy, School of Medicine, University of Crete, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"6250","published-online":{"date-parts":[[2025,6,30]]},"reference":[{"key":"ref0","doi-asserted-by":"crossref","unstructured":"1. 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Clinics (Sao Paulo). 2011; 66: 1347\u20131352. doi: 10.1590\/s1807-59322011000800007.","DOI":"10.1590\/S1807-59322011000800007"}],"container-title":["Journal of Ultrasonography"],"original-title":[],"deposited":{"date-parts":[[2025,12,29]],"date-time":"2025-12-29T14:57:51Z","timestamp":1767020271000},"score":1,"resource":{"primary":{"URL":"https:\/\/jultrason.pl\/index.php\/issues\/volume-25-no-101\/ultrasound-imaging-in-floppy-eyelid-syndrome-anatomical-and-clinical-considerations"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,30]]},"references-count":30,"journal-issue":{"issue":"101","published-online":{"date-parts":[[2025,6,30]]}},"URL":"https:\/\/doi.org\/10.15557\/jou.2025.0019","relation":{},"ISSN":["2084-8404","2451-070X"],"issn-type":[{"value":"2084-8404","type":"print"},{"value":"2451-070X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6,30]]}}}