{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T13:29:16Z","timestamp":1787318956154,"version":"build-2736575974"},"reference-count":0,"publisher":"Akademiai Kiado Zrt.","issue":"2","content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":["Acta Veterinaria Hungarica"],"published-print":{"date-parts":[[2015,6]]},"abstract":"<jats:p>\n                    The impact of long-term vaccination against\n                    <jats:italic>Coxiella burnetii<\/jats:italic>\n                    on the fertility of cows was studied. Double vaccinations three weeks apart at the start of the third trimester of gestation in each of two consecutive pregnancies were applied. The final study population consisted of 410 cows after the first vaccination round. Based on the odds ratios, the likelihood of early fetal loss (pregnancy loss following a positive pregnancy diagnosis before Day 90 of gestation) was higher in control cows (OR = 1.42) than in vaccinated cows. The final study population consisted of 336 cows after the second round of vaccination. According to the odds ratios, vaccinated\n                    <jats:italic>C. burnetii<\/jats:italic>\n                    seronegative cows were less likely to be subfertile (&gt; 3 AI) (OR = 0.4) compared to non-vaccinated seronegative animals, and the likelihood of early fetal loss was lower in vaccinated\n                    <jats:italic>C. burnetii<\/jats:italic>\n                    seropositive animals (OR = 0.3) compared to non-vaccinated seronegative cows. Seropositivity to\n                    <jats:italic>C. burnetii<\/jats:italic>\n                    was positively related to twin pregnancy after the two rounds of vaccination (OR = 2.1 and 3.5, respectively). These results indicate that two consecutive vaccination rounds against\n                    <jats:italic>C. burnetii<\/jats:italic>\n                    in advanced gestation reduce subfertility and early fetal loss in dairy cows.\n                  <\/jats:p>","DOI":"10.1556\/004.2015.020","type":"journal-article","created":{"date-parts":[[2015,6,7]],"date-time":"2015-06-07T23:54:30Z","timestamp":1433721270000},"page":"223-233","update-policy":"https:\/\/doi.org\/10.1556\/policypage.crossmark.crossref.2","source":"Crossref","is-referenced-by-count":9,"title":["Effects of long-term vaccination against Coxiella burnetii on the fertility of high-producing dairy cows"],"prefix":"10.1556","volume":"63","author":[{"given":"Irina","family":"Garcia-Ispierto","sequence":"first","affiliation":[{"name":"Department of Animal Production, University of Lleida and Agrotecnio Centre, University of Lleida, Avda. Alcalde Rovira Roure 191, 25198 Lleida, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irene","family":"L\u00f3pez-Helguera","sequence":"additional","affiliation":[{"name":"Department of Animal Production, University of Lleida and Agrotecnio Centre, University of Lleida, Avda. Alcalde Rovira Roure 191, 25198 Lleida, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joan","family":"Tutusaus","sequence":"additional","affiliation":[{"name":"Department of Animal Production, University of Lleida and Agrotecnio Centre, University of Lleida, Avda. Alcalde Rovira Roure 191, 25198 Lleida, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ram\u00f3n","family":"Mur-Novales","sequence":"additional","affiliation":[{"name":"Department of Animal Production, University of Lleida and Agrotecnio Centre, University of Lleida, Avda. Alcalde Rovira Roure 191, 25198 Lleida, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando","family":"L\u00f3pez-Gatius","sequence":"additional","affiliation":[{"name":"Department of Animal Production, University of Lleida and Agrotecnio Centre, University of Lleida, Avda. Alcalde Rovira Roure 191, 25198 Lleida, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"425","container-title":["Acta Veterinaria Hungarica"],"original-title":[],"link":[{"URL":"https:\/\/akjournals.com\/view\/journals\/004\/63\/2\/article-p223.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/akjournals.com\/view\/journals\/004\/63\/2\/article-p223.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/akjournals.com\/view\/journals\/004\/63\/2\/article-p223.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,7]],"date-time":"2023-06-07T16:51:54Z","timestamp":1686156714000},"score":1,"resource":{"primary":{"URL":"https:\/\/akjournals.com\/view\/journals\/004\/63\/2\/article-p223.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,6]]},"references-count":0,"journal-issue":{"issue":"2"},"URL":"https:\/\/doi.org\/10.1556\/004.2015.020","relation":{},"ISSN":["0236-6290","1588-2705"],"issn-type":[{"value":"0236-6290","type":"print"},{"value":"1588-2705","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,6]]}}}