{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T14:36:52Z","timestamp":1772548612598,"version":"3.50.1"},"reference-count":0,"publisher":"Akademiai Kiado Zrt.","issue":"3","content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":["Acta Veterinaria Hungarica"],"published-print":{"date-parts":[[2015,9]]},"abstract":"<jats:p>This study was designed to compare <jats:italic>Coxiella burnetii<\/jats:italic> antibody dynamics in heifers born to vaccinated or non-vaccinated dams in a single high-producing dairy herd chronically infected with the bacterium. Antibody dynamics were examined from birth to the postpartum period in replacement heifers (n = 14) born to non-vaccinated dams (n = 7) or to dams that had been vaccinated on gestation days 171\u2013177 (n = 7) and 192\u2013198. Samples of blood, milk, faeces, vaginal fluid, colostrum and cotyledons (the latter two only at parturition) were obtained in the dams over the period from gestation days 171\u2013177 to postpartum days 91\u201397. Blood samples were used to detect antibodies against <jats:italic>C. burnetii<\/jats:italic> and remaining samples for PCR identification of the bacterium. In their calves\/heifers, blood samples for antibody determinations were collected from birth to postpartum at the time points 1\u20137 and 22\u201328 days and 3, 6 and 12 months of age; 90\u201396 and 210\u2013216 days of gestation; and 22\u201328 days postpartum. All calves were born seronegative for <jats:italic>C. burnetii<\/jats:italic>. Irrespective of the shedding status of their mothers (7 were <jats:italic>C. burnetii<\/jats:italic> shedders), seroconversion occurred after colostrum intake in all calves born to seropositive cows (n = 9) and in two of three vaccinated seronegative dams. Thereafter antibody titres gradually declined and by 6 months of age all calves were seronegative. Seronegativity persisted until their first postpartum period. These findings indicate that cows vaccinated during advanced pregnancy transfer immunity to their calves via the colostrum. Maternal <jats:italic>C. burnetii<\/jats:italic> antibodies in calves persisted for three months in calves born both to seronegative vaccinated and seropositive dams.<\/jats:p>","DOI":"10.1556\/004.2015.031","type":"journal-article","created":{"date-parts":[[2015,9,29]],"date-time":"2015-09-29T09:09:52Z","timestamp":1443517792000},"page":"337-346","update-policy":"https:\/\/doi.org\/10.1556\/policypage.crossmark.crossref.2","source":"Crossref","is-referenced-by-count":4,"title":["Coxiella burnetii antibody dynamics in heifers born to vaccinated versus non-vaccinated dams in a chronically infected dairy herd"],"prefix":"10.1556","volume":"63","author":[{"given":"Joan","family":"Tutusaus","sequence":"first","affiliation":[{"name":"Agrotechnical Centre and Department of Animal Production, University of Lleida, Av. Alcalde Rovira Roure 191, 25198 Lleida, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irina","family":"Garcia-Ispierto","sequence":"additional","affiliation":[{"name":"Agrotechnical Centre and Department of Animal Production, University of Lleida, Av. Alcalde Rovira Roure 191, 25198 Lleida, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernando","family":"L\u00f3pez-Gatius","sequence":"additional","affiliation":[{"name":"Agrotechnical Centre and Department of Animal Production, University of Lleida, Av. Alcalde Rovira Roure 191, 25198 Lleida, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","container-title":["Acta Veterinaria Hungarica"],"original-title":[],"link":[{"URL":"https:\/\/akjournals.com\/view\/journals\/004\/63\/3\/article-p337.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/akjournals.com\/view\/journals\/004\/63\/3\/article-p337.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/akjournals.com\/view\/journals\/004\/63\/3\/article-p337.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,7]],"date-time":"2023-06-07T20:52:34Z","timestamp":1686171154000},"score":1,"resource":{"primary":{"URL":"https:\/\/akjournals.com\/view\/journals\/004\/63\/3\/article-p337.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,9]]},"references-count":0,"journal-issue":{"issue":"3"},"URL":"https:\/\/doi.org\/10.1556\/004.2015.031","relation":{},"ISSN":["0236-6290","1588-2705"],"issn-type":[{"value":"0236-6290","type":"print"},{"value":"1588-2705","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,9]]}}}