{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T16:12:39Z","timestamp":1771949559759,"version":"3.50.1"},"reference-count":0,"publisher":"Akademiai Kiado Zrt.","issue":"1","content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":["Acta Veterinaria Hungarica"],"published-print":{"date-parts":[[2017,3]]},"abstract":"<jats:p>Little is known about the inflammatory response of the endometrium in repeat-breeding cows with subclinical endometritis (SE). The objective of this study was to evaluate the mRNA expression of prostaglandin-endoperoxide synthase 2 <jats:italic>(PTGS 2)<\/jats:italic>, prostaglandin F2<jats:sub>\u03b1<\/jats:sub> synthase <jats:italic>(PTGFS)<\/jats:italic> and prostaglandin E2 microsomal synthase 1 <jats:italic>(mPTGES 1)<\/jats:italic> in the endometrium of repeat-breeding cows with and without SE. SE was diagnosed cytologically using the cytobrush method, with the threshold being set at 5% polymorphonuclear neutrophils. Biopsy samples were obtained from the endometrium of repeat-breeding cows with SE (n = 10) and without SE (n = 10). The mRNA expression of the synthases was evaluated using qRT-PCR. Significantly higher (P &lt; 0.05) expression of the <jats:italic>PTGS 2<\/jats:italic> gene was detected in the repeat breeders with SE, whereas there was no significant difference in the expression of <jats:italic>PTGFS<\/jats:italic> and <jats:italic>mPTGES 1<\/jats:italic> mRNAs between repeatbreeding cows with SE and those without it (P &gt; 0.05). Our study confirms that increased endometrial expression of the <jats:italic>PTGS 2<\/jats:italic> gene is involved in the inflammatory response in repeat breeders.<\/jats:p>","DOI":"10.1556\/004.2017.010","type":"journal-article","created":{"date-parts":[[2017,2,28]],"date-time":"2017-02-28T12:33:11Z","timestamp":1488285191000},"page":"96-104","update-policy":"https:\/\/doi.org\/10.1556\/policypage.crossmark.crossref.2","source":"Crossref","is-referenced-by-count":8,"title":["Endometrial mRNA expression of prostaglandin synthase enzymes PTGS 2, PTGFS and mPTGES 1 in repeat-breeding cows with cytologically determined endometritis"],"prefix":"10.1556","volume":"65","author":[{"given":"Tomasz","family":"Janowski","sequence":"first","affiliation":[{"name":"Department of Animal Reproduction with Clinic, University of Warmia and Mazury, Oczapowskiego 14, 10-719 Olsztyn, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wojciech","family":"Bara\u0144ski","sequence":"additional","affiliation":[{"name":"Department of Animal Reproduction with Clinic, University of Warmia and Mazury, Oczapowskiego 14, 10-719 Olsztyn, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karolina","family":"\u0141ukasik","sequence":"additional","affiliation":[{"name":"Department of Reproductive Immunology and Pathology, Institute of Animal Reproduction and Food Research of the Polish Academy of Science, Olsztyn, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dariusz","family":"Skar\u017cy\u0144ski","sequence":"additional","affiliation":[{"name":"Department of Reproductive Immunology and Pathology, Institute of Animal Reproduction and Food Research of the Polish Academy of Science, Olsztyn, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S\u0142awomir","family":"Zdu\u0144czyk","sequence":"additional","affiliation":[{"name":"Department of Animal Reproduction with Clinic, University of Warmia and Mazury, Oczapowskiego 14, 10-719 Olsztyn, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katarzyna","family":"Malinowska","sequence":"additional","affiliation":[{"name":"Department of Animal Reproduction with Clinic, University of Warmia and Mazury, Oczapowskiego 14, 10-719 Olsztyn, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","container-title":["Acta Veterinaria Hungarica"],"original-title":[],"link":[{"URL":"https:\/\/akjournals.com\/view\/journals\/004\/65\/1\/article-p96.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/akjournals.com\/view\/journals\/004\/65\/1\/article-p96.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/akjournals.com\/view\/journals\/004\/65\/1\/article-p96.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,7]],"date-time":"2023-06-07T20:58:01Z","timestamp":1686171481000},"score":1,"resource":{"primary":{"URL":"https:\/\/akjournals.com\/view\/journals\/004\/65\/1\/article-p96.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,3]]},"references-count":0,"journal-issue":{"issue":"1"},"URL":"https:\/\/doi.org\/10.1556\/004.2017.010","relation":{},"ISSN":["0236-6290","1588-2705"],"issn-type":[{"value":"0236-6290","type":"print"},{"value":"1588-2705","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,3]]}}}