{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,3]],"date-time":"2026-01-03T21:08:09Z","timestamp":1767474489234},"reference-count":0,"publisher":"Akademiai Kiado Zrt.","issue":"1","license":[{"start":{"date-parts":[[2018,3,1]],"date-time":"2018-03-01T00:00:00Z","timestamp":1519862400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":["Acta Veterinaria Hungarica"],"published-print":{"date-parts":[[2018,3]]},"abstract":"<jats:p>\n          <jats:italic>Babesia vesperuginis<\/jats:italic> is the only piroplasm known to infect bats. Unlike most members of the genus <jats:italic>Babesia<\/jats:italic>, it is probably transmitted by a soft tick species (i.e. <jats:italic>Argas vespertilionis<\/jats:italic>). Recently, two studies have been conducted to clarify the phylogenetic status of this species, and both agreed on placing it into a basal position among <jats:italic>Babesia<\/jats:italic> sensu stricto (s.s.). However, several important groups of piroplasms were not included in the already reported phylogenetic trees of <jats:italic>B. vesperuginis<\/jats:italic> isolates. Therefore, the aim of the present study was to amplify an approx. 950-bp fragment of the cytochrome <jats:italic>c<\/jats:italic> oxidase subunit 1 (<jats:italic>cox1<\/jats:italic>) gene of <jats:italic>B. vesperuginis<\/jats:italic> from <jats:italic>A. vespertilionis<\/jats:italic> specimens, and to compare its sequences with those from other piroplasmid groups in a broader phylogenetic context. Sequence comparisons focusing on either 18S rRNA or <jats:italic>cox1<\/jats:italic> genes, as well as phylogenetic analyses involving separate and concatenated 18S rRNA and <jats:italic>cox1<\/jats:italic> sequences indicate that <jats:italic>B. vesperuginis<\/jats:italic> is more closely related to the phylogenetic group of Theileriidae than to <jats:italic>Babesia<\/jats:italic> s.s. In particular, <jats:italic>B. vesperuginis<\/jats:italic> clustered closest to <jats:italic>Cytauxzoon felis<\/jats:italic> and the \u2018prototheilerid\u2019 <jats:italic>B. conradae<\/jats:italic>. The results of this study highlight that <jats:italic>B. vesperuginis<\/jats:italic> is a unique and taxonomically important species, which should be included in future studies aimed at resolving the comprehensive phylogeny of Piroplasmida.<\/jats:p>","DOI":"10.1556\/004.2018.010","type":"journal-article","created":{"date-parts":[[2018,3,27]],"date-time":"2018-03-27T07:23:28Z","timestamp":1522135408000},"page":"107-115","update-policy":"http:\/\/dx.doi.org\/10.1556\/policypage.crossmark.crossref.2","source":"Crossref","is-referenced-by-count":10,"title":["Analyses of separate and concatenated cox1 and 18S rRNA gene sequences indicate that the bat piroplasm Babesia vesperuginis is phylogenetically close to Cytauxzoon felis and the \u2018prototheilerid\u2019 Babesia conradae"],"prefix":"10.1556","volume":"66","author":[{"given":"S\u00e1ndor","family":"Hornok","sequence":"first","affiliation":[{"name":"Department of Parasitology and Zoology, University of Veterinary Medicine, Istv\u00e1n u. 2, H-1078 Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandra","family":"Corduneanu","sequence":"additional","affiliation":[{"name":"Department of Parasitology and Parasitic Diseases, University of Agricultural Sciences and Veterinary Medicine, Cluj-Napoca, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jen\u0151","family":"Kontsch\u00e1n","sequence":"additional","affiliation":[{"name":"Plant Protection Institute, Centre for Agricultural Research, Hungarian Academy of Sciences, Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katinka","family":"Bek\u0151","sequence":"additional","affiliation":[{"name":"Institute for Veterinary Medical Research, Centre for Agricultural Research, Hungarian Academy of Sciences, Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Krisztina","family":"Sz\u0151ke","sequence":"additional","affiliation":[{"name":"Department of Parasitology and Zoology, University of Veterinary Medicine, Istv\u00e1n u. 2, H-1078 Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tam\u00e1s","family":"G\u00f6rf\u00f6l","sequence":"additional","affiliation":[{"name":"Department of Zoology, Hungarian Natural History Museum, Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mikl\u00f3s","family":"Gyuranecz","sequence":"additional","affiliation":[{"name":"Institute for Veterinary Medical Research, Centre for Agricultural Research, Hungarian Academy of Sciences, Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Attila D.","family":"S\u00e1ndor","sequence":"additional","affiliation":[{"name":"Department of Parasitology and Parasitic Diseases, University of Agricultural Sciences and Veterinary Medicine, Cluj-Napoca, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","container-title":["Acta Veterinaria Hungarica"],"original-title":[],"link":[{"URL":"https:\/\/akjournals.com\/view\/journals\/004\/66\/1\/article-p107.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/akjournals.com\/view\/journals\/004\/66\/1\/article-p107.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/akjournals.com\/view\/journals\/004\/66\/1\/article-p107.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,7]],"date-time":"2023-06-07T21:03:12Z","timestamp":1686171792000},"score":1,"resource":{"primary":{"URL":"https:\/\/akjournals.com\/view\/journals\/004\/66\/1\/article-p107.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,3]]},"references-count":0,"journal-issue":{"issue":"1"},"URL":"https:\/\/doi.org\/10.1556\/004.2018.010","relation":{},"ISSN":["0236-6290","1588-2705"],"issn-type":[{"value":"0236-6290","type":"print"},{"value":"1588-2705","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,3]]}}}