{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,7,5]],"date-time":"2024-07-05T04:32:58Z","timestamp":1720153978076},"reference-count":16,"publisher":"Akademiai Kiado Zrt.","issue":"1","content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":["Acta Veterinaria Hungarica"],"published-print":{"date-parts":[[2019,3]]},"abstract":"<jats:p>At clinical examination, a 5-year-old male domestic short-haired cat exhibited painful swelling and erythema of the pinnae of both ears. Microscopically, the lesions on both pinnae were composed of diffuse granulomatous chondritis with degeneration and necrosis of the pinnal cartilage. Numerous mast cells were also observed within and surrounding the inflammatory lesion. Immunohistochemistry showed a mixed inflammatory infiltrate characterised by the predominance of macrophages (CD68+, MAC 387+ and Lysozyme+), T lymphocytes (CD3+), some B lymphocytes (CD79\u03b1+) and neutrophils. Immunopathological characterisation of the lesion showed a granulomatous inflammation profile and suggests that the morphological changes and immunopathogenesis of auricular chondritis in cats presents a similarity with relapsing polychondritis in humans.<\/jats:p>","DOI":"10.1556\/004.2019.009","type":"journal-article","created":{"date-parts":[[2019,3,29]],"date-time":"2019-03-29T06:42:47Z","timestamp":1553841767000},"page":"81-86","update-policy":"http:\/\/dx.doi.org\/10.1556\/policypage.crossmark.crossref.1","source":"Crossref","is-referenced-by-count":2,"title":["Immunopathological findings in a cat with auricular chondritis"],"prefix":"10.1556","volume":"67","author":[{"given":"Tais","family":"Meziara Wilson","sequence":"first","affiliation":[{"name":"1 Laboratory of Veterinary Pathology, 70330-050 Bras\u00edlia, DF, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mizael","family":"Machado","sequence":"additional","affiliation":[{"name":"1 Laboratory of Veterinary Pathology, 70330-050 Bras\u00edlia, DF, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Davi Emanuel Ribeiro","family":"De Sousa","sequence":"additional","affiliation":[{"name":"1 Laboratory of Veterinary Pathology, 70330-050 Bras\u00edlia, DF, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tain\u00e3","family":"Bra\u00fana","sequence":"additional","affiliation":[{"name":"2 Small Animal Veterinary Hospital, School of Veterinary Medicine, University of Bras\u00edlia, Federal District, 70330-050 Bras\u00edlia, DF, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rafael","family":"Torres Neto","sequence":"additional","affiliation":[{"name":"3 VetMol Laboratory, Botucatu, S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ren\u00e9e","family":"Laufer-Amorim","sequence":"additional","affiliation":[{"name":"4 School of Veterinary Medicine and Animal Science, S\u00e3o Paulo State University, Botucatu, S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matias Pablo Juan","family":"Szab\u00f3","sequence":"additional","affiliation":[{"name":"5 Ixodology Laboratory, Faculty of Veterinary Medicine, Federal University of Uberl\u00e2ndia, MG, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcio Botelho","family":"De Castro","sequence":"additional","affiliation":[{"name":"1 Laboratory of Veterinary Pathology, 70330-050 Bras\u00edlia, DF, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","reference":[{"key":"rf1","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/929075"},{"key":"rf2","doi-asserted-by":"publisher","DOI":"10.5607\/en.2017.26.1.66"},{"key":"rf3","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.14229"},{"key":"rf4","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2013.07.005"},{"key":"rf5","doi-asserted-by":"publisher","DOI":"10.1292\/jvms.71.79"},{"key":"rf6","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1136\/vr.159.20.677","volume":"159","author":"Bleul U.","year":"2006","journal-title":"Vet. 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