{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T17:51:06Z","timestamp":1760205066576,"version":"3.37.3"},"reference-count":64,"publisher":"Akademiai Kiado Zrt.","issue":"1","license":[{"start":{"date-parts":[[2020,3,30]],"date-time":"2020-03-30T00:00:00Z","timestamp":1585526400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003549","name":"Hungarian Scientific Research Fund","doi-asserted-by":"crossref","award":["K127916"],"award-info":[{"award-number":["K127916"]}],"id":[{"id":"10.13039\/501100003549","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":["AVet"],"published-print":{"date-parts":[[2020,3,30]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Two adult barbels (<jats:italic>Barbus barbus<\/jats:italic>) with visible skin tumours were subjected to histopathological and molecular examinations. The fish were caught in the River Danube near Budapest. Papillomas were found around their oral cavity, at the operculum and at the pectoral fins, while epidermal hyperplasias were seen on the body surface. Cyprinid herpesvirus 1 (CyHV-1) was detected in the kidney of the specimens by polymerase chain reaction (PCR), and barbel circovirus 1 (BaCV1) was found in all internal organs and in the tissues of the tumours. The whole genome of BaCV1 and three conserved genes from the genome of CyHV-1 were sequenced. Previously, BaCV1 had been reported only once from a mass mortality event among barbel fry. The whole genome sequence of our circovirus shared 99.9% nucleotide identity with that of the formerly reported BaCV1. CyHV-1 is known to infect common carp and coloured carp (<jats:italic>Cyprinus carpio<\/jats:italic>), and has been assumed to infect other cyprinid fish species as well. We found the nucleotide sequences of the genes of CyHV-1 to be identical in 98.7% to those of the previous isolates from carp. To the best of our knowledge, this is the first molecular confirmation of the presence of CyHV-1 DNA in cyprinid fish species other than carp.<\/jats:p>","DOI":"10.1556\/004.2020.00004","type":"journal-article","created":{"date-parts":[[2020,5,8]],"date-time":"2020-05-08T08:57:33Z","timestamp":1588928253000},"page":"112-116","update-policy":"https:\/\/doi.org\/10.1556\/policypage.crossmark.crossref.1","source":"Crossref","is-referenced-by-count":7,"title":["Detection of cyprinid herpesvirus 1 (CyHV-1) in barbel (Barbus barbus): First molecular evidence for the presence of CyHV-1 in fish other than carp (Cyprinus carpio)"],"prefix":"10.1556","volume":"68","author":[{"given":"R\u00e9ka","family":"Borz\u00e1k","sequence":"first","affiliation":[{"name":"1Institute for Veterinary Medical Research, Centre for Agricultural Research, P.O. Box 18, Budapest, H-1581, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bogl\u00e1rka","family":"Sellyei","sequence":"additional","affiliation":[{"name":"1Institute for Veterinary Medical Research, Centre for Agricultural Research, P.O. Box 18, Budapest, H-1581, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ferenc","family":"Baska","sequence":"additional","affiliation":[{"name":"2Department of Exotic Animal and Wildlife Medicine, University of Veterinary Medicine, Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Csaba","family":"Sz\u00e9kely","sequence":"additional","affiliation":[{"name":"1Institute for Veterinary Medical Research, Centre for Agricultural Research, P.O. Box 18, Budapest, H-1581, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8645-9514","authenticated-orcid":true,"given":"Andor","family":"Doszpoly","sequence":"additional","affiliation":[{"name":"1Institute for Veterinary Medical Research, Centre for Agricultural Research, P.O. Box 18, Budapest, H-1581, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","reference":[{"key":"ref11","first-page":"115","article-title":"An investigation into the occurrence of epidermal hyperplasia and papilloma in barbel (Barbus barbus L.) from a river in southern England","volume":"13","author":"Barnes","year":"1993","journal-title":"Bull. Eur. Assoc. 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Microbiol."},{"key":"ref21","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1556\/004.2017.026","article-title":"Molecular detection and genome analysis of circoviruses of European eel (Anguilla anguilla) and sichel (Pelecus cultratus)","volume":"65","author":"Borz\u00e1k","year":"2017","journal-title":"Acta Vet. Hung."},{"key":"ref541","first-page":"234","article-title":"Skin and gonadal tumours in a barbel (Barbus barbus) \u2013 a case report","volume":"27","author":"Palikova","year":"2007","journal-title":"Bull. Eur. Assoc. Fish Pathol."},{"key":"ref611","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/j.envpol.2003.11.011","article-title":"The intestinal parasite Pomphorhynchus laevis (Acanthocephala) from barbel as a bioindicator for metal pollution in the Danube River near Budapest, Hungary","volume":"129","author":"Thielen","year":"2004","journal-title":"Environ. Pollut."},{"key":"ref561","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1002\/9781118222942.ch5","article-title":"Neoplasia of teleosts","author":"Roberts","year":"2012","journal-title":"Fish Pathology"},{"key":"ref141","doi-asserted-by":"crossref","first-page":"1817","DOI":"10.1099\/vir.0.031344-0","article-title":"First detection and analysis of a fish circovirus","volume":"92","author":"L\u0151rincz","year":"2011","journal-title":"J. Gen. Virol."},{"key":"ref581","doi-asserted-by":"crossref","DOI":"10.1111\/vde.12482","article-title":"Detection of Cyprinid Herpesvirus 1 DNA in cutaneous squamous cell carcinoma of koi carp (Cyprinus carpio)","volume":"29","author":"Sirri","year":"2018","journal-title":"Vet. Dermatol."},{"key":"ref51","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1007\/s00705-008-0278-4","article-title":"The order Herpesvirales","volume":"154","author":"Davison","year":"2009","journal-title":"Arch. 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Org."},{"key":"ref251","article-title":"A herpesvirus isolated from carp papilloma in Japan","author":"Sano","year":"1985","journal-title":"Fish and Shellfish Pathology"},{"key":"ref551","article-title":"Family Herpesviridae","author":"Pellett","year":"2011","journal-title":"Virus Taxonomy, IXth Report of the International Committee on Taxonomy of Viruses"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/S0378-1135(01)00492-8","article-title":"Evolution of the herpesviruses","volume":"86","author":"Davison","year":"2002","journal-title":"Vet. Microbiol."},{"key":"ref311","doi-asserted-by":"crossref","first-page":"87","DOI":"10.3354\/dao02340","article-title":"First detection of pike fry-like rhabdovirus in barbel and spring viraemia of carp virus in sturgeon and pike in aquaculture in the Czech Republic","volume":"95","author":"Vicenova","year":"2011","journal-title":"Dis. Aquat. 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Virol."},{"key":"ref71","article-title":"Virus diseases of cyprinids","author":"Dixon","year":"2008","journal-title":"Fish Diseases, Book 1"},{"key":"ref111","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.virusres.2007.11.001","article-title":"Detection of a novel circovirus in mute swans (Cygnus olor) by using nested broad-spectrum PCR","volume":"132","author":"Halami","year":"2008","journal-title":"Virus Res."},{"key":"ref31","doi-asserted-by":"crossref","first-page":"1997","DOI":"10.1099\/jgv.0.000871","article-title":"ICTV virus taxonomy profile: circoviridae","volume":"98","author":"Breitbart","year":"2017","journal-title":"J. Gen. Virol."},{"key":"ref621","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.vetmic.2003.10.010","article-title":"Avian circovirus diseases: lessons for the study of PMWS","volume":"98","author":"Todd","year":"2004","journal-title":"Vet. 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Hung."},{"key":"ref381","doi-asserted-by":"crossref","first-page":"2908","DOI":"10.1128\/JVI.03206-12","article-title":"Comparative genomics of carp herpesviruses","volume":"87","author":"Davison","year":"2013","journal-title":"J. Virol."}],"container-title":["Acta Veterinaria Hungarica"],"original-title":[],"link":[{"URL":"https:\/\/akjournals.com\/view\/journals\/004\/68\/1\/article-p112.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/akjournals.com\/downloadpdf\/journals\/004\/68\/1\/article-p112.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,11,20]],"date-time":"2021-11-20T04:41:09Z","timestamp":1637383269000},"score":1,"resource":{"primary":{"URL":"https:\/\/akjournals.com\/view\/journals\/004\/68\/1\/article-p112.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,3,30]]},"references-count":64,"journal-issue":{"issue":"1"},"URL":"https:\/\/doi.org\/10.1556\/004.2020.00004","relation":{},"ISSN":["0236-6290","1588-2705"],"issn-type":[{"type":"print","value":"0236-6290"},{"type":"electronic","value":"1588-2705"}],"subject":[],"published":{"date-parts":[[2020,3,30]]}}}