{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T05:08:37Z","timestamp":1747199317087,"version":"3.40.5"},"reference-count":108,"publisher":"Akademiai Kiado Zrt.","issue":"2","content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":["AVet"],"published-print":{"date-parts":[[2020,6,30]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>An 11-year-old Hanoverian gelding used for jumping was evaluated for gait abnormalities and hoof problems in the hindlimbs. Clinical examinations revealed signs consistent with shivers. A thyroid gland enlargement was noticed, baseline serum thyroid hormone (TH) concentrations were low, and a low response to thyrotropin-releasing hormone administration was observed. Hypothyroidism was suspected. The horse was treated with levothyroxine for 1 year. TH concentrations returned to the normal range by week 4 of treatment. Thirty weeks after the initiation of levothyroxine therapy, the gait abnormality improved. Our findings suggest that the assessment of thyroid status and especially of the subclinical thyroid gland disorders in horses affected with shivering, as well as evaluation of the effects of levothyroxine on the improvement of clinical signs could be promising in establishing the aetiopathogenesis and\/or treatment of shivering in horses.<\/jats:p>","DOI":"10.1556\/004.2020.00026","type":"journal-article","created":{"date-parts":[[2020,10,15]],"date-time":"2020-10-15T03:01:11Z","timestamp":1602730871000},"page":"147-153","update-policy":"https:\/\/doi.org\/10.1556\/policypage.crossmark.crossref.1","source":"Crossref","is-referenced-by-count":1,"title":["Improvement of the clinical signs of gait abnormality after treatment with levothyroxine in a horse with shivering and hypothyroidism"],"prefix":"10.1556","volume":"68","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4564-745X","authenticated-orcid":true,"given":"Aram","family":"Saadi","sequence":"first","affiliation":[{"name":"1Department of Internal Medicine and Clinical Pathology, Faculty of Veterinary Medicine, Urmia University, P.O. Box 57561-51818, Urmia, Islamic Republic of Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bahram","family":"Dalir-Naghadeh","sequence":"additional","affiliation":[{"name":"1Department of Internal Medicine and Clinical Pathology, Faculty of Veterinary Medicine, Urmia University, P.O. Box 57561-51818, Urmia, Islamic Republic of Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hamid","family":"Akbari","sequence":"additional","affiliation":[{"name":"2Department of Clinical Sciences, Faculty of Veterinary Medicine, University of Tabriz, Tabriz, Islamic Republic of Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mojtaba","family":"Rashedi","sequence":"additional","affiliation":[{"name":"3Department of Clinical Sciences, Faculty of Veterinary Medicine, Urmia University, Urmia, Islamic Republic of Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rahim","family":"Mohammadi","sequence":"additional","affiliation":[{"name":"4Department of Surgery and Diagnostic Imaging, Faculty of Veterinary Medicine, Urmia University, Urmia, Islamic Republic of Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","reference":[{"key":"ref911","doi-asserted-by":"crossref","first-page":"1763","DOI":"10.1016\/j.joms.2013.03.010","article-title":"Functional effects of local administration of thyroid hormone combined with chitosan conduit after sciatic nerve transection in rats","volume":"71","author":"Mohammadi","year":"2013","journal-title":"J. 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