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A <jats:italic>Coxiella burnetii<\/jats:italic> prevalence of 97.6% has been found by ELISA and PCR tests of the bulk tank milk in dairy cattle farms of Hungary. The herd- and individual-level seroprevalence rates of <jats:italic>C. burnetii<\/jats:italic> in the examined dairy cows and farms have dramatically increased over the past ten years. Three high-producing industrial dairy farms were studied which had previously been found ELISA and PCR positive for <jats:italic>C. burnetii<\/jats:italic> by bulk tank milk testing. <jats:italic>Coxiella burnetii<\/jats:italic> was detected in 52% of the 321 cows tested by ELISA. Pregnancy loss was detected in 18% of the cows between days 29\u201335 and days 60\u201370 of gestation. The study found a higher seropositivity rate (80.5%) in the cows that had lost their pregnancy and a seropositivity of 94.4% in the first-bred cows that had lost their pregnancy at an early stage. The ELISA-positive pregnant and aborted cows were further investigated by the complement fixation test (CFT). In dairy herds an average of 66.6% individual seropositivity was detected by the CFT (Phase II) in previously ELISA-positive animals that had lost their pregnancy and 64.5% in the pregnant animals. A higher (Phase I) seropositivity rate (50.0%) was found in the cows with pregnancy loss than in the pregnant animals (38.5%). The high prevalence of <jats:italic>C. burnetii<\/jats:italic> in dairy farms is a major risk factor related to pregnancy loss.<\/jats:p>","DOI":"10.1556\/004.2020.00035","type":"journal-article","created":{"date-parts":[[2020,11,7]],"date-time":"2020-11-07T03:00:17Z","timestamp":1604718017000},"page":"305-309","update-policy":"https:\/\/doi.org\/10.1556\/policypage.crossmark.crossref.1","source":"Crossref","is-referenced-by-count":9,"title":["Serological screening for Coxiella burnetii in the context of early pregnancy loss in dairy cows"],"prefix":"10.1556","volume":"68","author":[{"given":"Attila","family":"Dobos","sequence":"first","affiliation":[{"name":"1CEVA-Phylaxia Co. Ltd., Sz\u00e1ll\u00e1s u. 5., H-1107, Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gy\u00f6rgy","family":"G\u00e1bor","sequence":"additional","affiliation":[{"name":"2Androvet Ltd., Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Enik\u0151","family":"Wehmann","sequence":"additional","affiliation":[{"name":"3Institute for Veterinary Medical Research, Centre for Agricultural Research, Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B\u00e9la","family":"D\u00e9nes","sequence":"additional","affiliation":[{"name":"4National Food Chain Safety Office, Veterinary Diagnostic Directorate, Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bettina","family":"P\u00f3th-Szebenyi","sequence":"additional","affiliation":[{"name":"5National Agricultural Research and Innovation Centre, Research Institute for Animal Breeding, Nutrition and Meat Science, Herceghalom, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00c1ron B.","family":"Kov\u00e1cs","sequence":"additional","affiliation":[{"name":"3Institute for Veterinary Medical Research, Centre for Agricultural Research, Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mikl\u00f3s","family":"Gyuranecz","sequence":"additional","affiliation":[{"name":"3Institute for Veterinary Medical Research, Centre for Agricultural Research, Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","reference":[{"key":"ref201","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/S0007-1935(95)80176-6","article-title":"Early reproductive loss due to bovine pestivirus infection","volume":"151","author":"McGowan","year":"1995","journal-title":"Br. 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