{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,12]],"date-time":"2025-06-12T16:06:18Z","timestamp":1749744378750,"version":"3.37.3"},"reference-count":23,"publisher":"Akademiai Kiado Zrt.","issue":"3","funder":[{"DOI":"10.13039\/501100005667","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa e Inova\u00e7\u00e3o do Estado de Santa Catarina","doi-asserted-by":"crossref","award":["FAPESC, 05\/2018 \u2013 No.: 2019TR702"],"award-info":[{"award-number":["FAPESC, 05\/2018 \u2013 No.: 2019TR702"]}],"id":[{"id":"10.13039\/501100005667","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":["AVet"],"published-print":{"date-parts":[[2022,10,6]]},"abstract":"Abstract<\/jats:title>\n A case of non-communicating hydrocephalus and microcephaly in a sheep fetus infected with Neospora caninum<\/jats:italic> from Lages, Santa Catarina, Brazil, is reported. Macroscopically, there was moderate flattening and narrowing of the skull, and the portion of the cerebral hemispheres was markedly reduced in size, measuring 3.5\u2009\u00d7\u20093.5\u2009\u00d7\u20090.5\u2009cm, with marked diffuse flattening of the brain gyri and dilation of the lateral ventricles. Cerebrospinal fluid samples were positive to N. caninum<\/jats:italic> detection by PCR. Histologically, there was discrete focal lymphoplasmacytic necrotising encephalitis on the floor of the lateral ventricle, discrete multifocal gliosis and discrete multifocal lymphoplasmacytic myositis. Through the molecular detection of N. caninum<\/jats:italic> in the cerebrospinal fluid, it was possible to report what appears to be the first\u00a0case of non-communicating hydrocephalus and microcephaly in an ovine fetus infected with N.\u00a0caninum<\/jats:italic>.<\/jats:p>","DOI":"10.1556\/004.2022.00028","type":"journal-article","created":{"date-parts":[[2022,9,21]],"date-time":"2022-09-21T11:33:42Z","timestamp":1663760022000},"page":"226-229","update-policy":"https:\/\/doi.org\/10.1556\/policypage.crossmark.crossref.1","source":"Crossref","is-referenced-by-count":6,"title":["Microcephaly and hydrocephalus in a sheep fetus infected with Neospora caninum in Southern Brazil \u2013 Short communication"],"prefix":"10.1556","volume":"70","author":[{"given":"J\u00e9ssica Aline","family":"Withoeft","sequence":"first","affiliation":[{"name":"Laborat\u00f3rio de Patologia Animal, Centro de Ci\u00eancias Agroveterin\u00e1rias, Universidade do Estado de Santa Catarina - Av. Lu\u00eds de Cam\u00f5es, 2090, Conta Dinheiro, Lages, Santa Catarina, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leonardo Silva","family":"Da Costa","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Patologia Animal, Centro de Ci\u00eancias Agroveterin\u00e1rias, Universidade do Estado de Santa Catarina - Av. Lu\u00eds de Cam\u00f5es, 2090, Conta Dinheiro, Lages, Santa Catarina, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucas","family":"Marian","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Patologia Animal, Centro de Ci\u00eancias Agroveterin\u00e1rias, Universidade do Estado de Santa Catarina - Av. 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