{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T14:02:04Z","timestamp":1784037724106,"version":"3.55.0"},"reference-count":21,"publisher":"Akademiai Kiado Zrt.","issue":"1","content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":["AVet"],"published-print":{"date-parts":[[2023,6,20]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This study investigated the frequency of third-generation cephalosporin resistance in <jats:italic>Klebsiella<\/jats:italic> spp. isolated from animals in Croatia and the presence of <jats:italic>bla<\/jats:italic><jats:sub>CTX-M<\/jats:sub> genes. A total of 711 enteric bacteria were isolated from clinical samples, and <jats:italic>Klebsiella<\/jats:italic> spp. isolates accounted for 6.9% (<jats:italic>n<\/jats:italic> = 49). Thirteen <jats:italic>Klebsiella<\/jats:italic> isolates (26.5%) were ESBL producers, nine isolates from the <jats:italic>Klebsiella pneumoniae<\/jats:italic> species complex (69.2%), and four (30.8%) <jats:italic>Klebsiella oxytoca<\/jats:italic> isolates. All carried the <jats:italic>bla<\/jats:italic><jats:sub>CTX-M-15<\/jats:sub> gene, and antimicrobial susceptibility testing revealed them as multidrug resistant. All were resistant to all tested cephalosporins, fluoroquinolones, aminoglycosides and aztreonam, 92.3% showed resistance to tetracycline, 84.6% to trimethoprim-sulfamethoxazole and 69.2% to nitrofurantoin. No isolate showed resistance to imipenem and meropenem. It can be concluded that ESBL-producing <jats:italic>Klebsiella<\/jats:italic> expressing the <jats:italic>bla<\/jats:italic><jats:sub>CTX-M<\/jats:sub> gene are not rare among <jats:italic>Klebsiella<\/jats:italic> isolates from animals in Croatia.<\/jats:p>","DOI":"10.1556\/004.2023.00845","type":"journal-article","created":{"date-parts":[[2023,4,7]],"date-time":"2023-04-07T06:28:52Z","timestamp":1680848932000},"page":"12-15","update-policy":"https:\/\/doi.org\/10.1556\/policypage.crossmark.crossref.2","source":"Crossref","is-referenced-by-count":2,"title":["Detection of blaCTX-M genes in ESBL-producing Klebsiella isolates from animals in Croatia"],"prefix":"10.1556","volume":"71","author":[{"given":"Selma","family":"Pintari\u0107","sequence":"first","affiliation":[{"name":"Department of Microbiology and Infectious Diseases with Clinic, Faculty of Veterinary Medicine, University of Zagreb, Heinzelova 55, Zagreb, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9202-7961","authenticated-orcid":true,"given":"Zrinka","family":"\u0160tritof","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Infectious Diseases with Clinic, Faculty of Veterinary Medicine, University of Zagreb, Heinzelova 55, Zagreb, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vesna Moj\u010dec","family":"Perko","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Infectious Diseases with Clinic, Faculty of Veterinary Medicine, University of Zagreb, Heinzelova 55, Zagreb, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Tumpa","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biochemistry, Faculty of Veterinary Medicine, University of Zagreb, Heinzelova 55, Zagreb, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marija","family":"Cvetni\u0107","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Infectious Diseases with Clinic, Faculty of Veterinary Medicine, University of Zagreb, Heinzelova 55, Zagreb, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lana","family":"Had\u017ei\u0107","sequence":"additional","affiliation":[{"name":"Laboratory for Food, Water and Animal Feed Microbiology, PI \u2018Veterinary Institute\u2019, Biha\u0107, Bosnia and Herzegovina"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"425","reference":[{"key":"B1","series-title":"Appl. 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