{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,6,7]],"date-time":"2023-06-07T21:11:04Z","timestamp":1686172264296},"reference-count":0,"publisher":"Akademiai Kiado Zrt.","issue":"2","content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":["Acta Veterinaria Hungarica"],"published-print":{"date-parts":[[2001,4]]},"abstract":"<jats:p>The aim of the present study was to evaluate the presence of lymphocytes and granulocytes in different stages of embryonic development and on the first posthatching day. The lymphocytes present in the bursa of Fabricius and thymus were evaluated by histological analysis of the yolk sac, bursa of Fabricius, thymus, liver and bone marrow of 100 chicken embryos divided into groups and treated with: (I) Marek\u2019s disease vaccine as viral antigen, (II) Marek\u2019s disease vaccine plus lymphokines, (III) lymphokines, and (IV) vaccine diluent. Group V was not treated. Samples were taken on days 14, 17 and 20 of incubation and on the first posthatching day. An increase in the number of epithelial matrix as precursors of lymphoid follicles was observed in the bursa of Fabricius of embryos inoculated with lymphokines compared to embryos in all the other groups (p &lt; 0.05). In addition, a higher amount of granulocytes was found in the yolk sac and liver of embryos inoculated with lymphokines than in the embryos of all other groups (p &lt; 0.05). In the bone marrow, no significant difference was observed among the treated groups concerning the amount of granulocytes. The results suggest that administration of antigens or protein molecules at an early stage of embryonic development increases the presence of granulocytes in the liver and granulopoiesis in the yolk sac, and also increases the number of epithelial matrixs in the bursa of Fabricius.<\/jats:p>","DOI":"10.1556\/004.49.2001.2.5","type":"journal-article","created":{"date-parts":[[2015,12,4]],"date-time":"2015-12-04T13:43:00Z","timestamp":1449236580000},"page":"163-174","update-policy":"http:\/\/dx.doi.org\/10.1556\/policypage.crossmark.crossref.2","source":"Crossref","is-referenced-by-count":1,"title":["Histological evaluation of immune organs in chicken embryos inoculated with Marek\u2019s disease virus and lymphokines"],"prefix":"10.1556","volume":"49","author":[{"given":"Mireya","family":"Ortiz","sequence":"first","affiliation":[{"name":"Departamento de Producti\u00f3n Animal: Aves, Facultad de Medicina, Veterinaria y Zootecnia, Universidad Nacional Aut\u00f3noma de M\u00e9xico, 04510 Ciudad Universitaria, Coyoac\u00e1n, M\u00e9xico D. F., M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V. M.","family":"Petrone","sequence":"additional","affiliation":[{"name":"Departamento de Producti\u00f3n Animal: Aves, Facultad de Medicina, Veterinaria y Zootecnia, Universidad Nacional Aut\u00f3noma de M\u00e9xico, 04510 Ciudad Universitaria, Coyoac\u00e1n, M\u00e9xico D. F., M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"T\u00e9llez","sequence":"additional","affiliation":[{"name":"Departamento de Producti\u00f3n Animal: Aves, Facultad de Medicina, Veterinaria y Zootecnia, Universidad Nacional Aut\u00f3noma de M\u00e9xico, 04510 Ciudad Universitaria, Coyoac\u00e1n, M\u00e9xico D. F., M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Feh\u00e9rv\u00e1ri","sequence":"additional","affiliation":[{"name":"Departamento de Producti\u00f3n Animal: Aves, Facultad de Medicina, Veterinaria y Zootecnia, Universidad Nacional Aut\u00f3noma de M\u00e9xico, 04510 Ciudad Universitaria, Coyoac\u00e1n, M\u00e9xico D. F., M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","container-title":["Acta Veterinaria Hungarica"],"original-title":[],"link":[{"URL":"https:\/\/akjournals.com\/view\/journals\/004\/49\/2\/article-p163.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/akjournals.com\/view\/journals\/004\/49\/2\/article-p163.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/akjournals.com\/view\/journals\/004\/49\/2\/article-p163.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,7]],"date-time":"2023-06-07T20:48:08Z","timestamp":1686170888000},"score":1,"resource":{"primary":{"URL":"https:\/\/akjournals.com\/view\/journals\/004\/49\/2\/article-p163.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,4]]},"references-count":0,"journal-issue":{"issue":"2"},"URL":"https:\/\/doi.org\/10.1556\/004.49.2001.2.5","relation":{},"ISSN":["0236-6290","1588-2705"],"issn-type":[{"value":"0236-6290","type":"print"},{"value":"1588-2705","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001,4]]}}}