{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T05:09:31Z","timestamp":1747199371262,"version":"3.40.5"},"reference-count":44,"publisher":"Akademiai Kiado Zrt.","issue":"4","content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":["AMicr"],"published-print":{"date-parts":[[2020,12,17]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Saprochaete clavata<\/jats:italic> is an emerging opportunistic pathogen, that causes life-threatening infections, but there are limited evidence and information about the evaluation of <jats:italic>in vitro<\/jats:italic> antifungal susceptibility test results. The aim of this study was to determine <jats:italic>S. clavata<\/jats:italic> isolates from clinical specimens and to investigate their <jats:italic>in vitro<\/jats:italic> antifungal susceptibility. <jats:italic>S. clavata<\/jats:italic> was identified by API ID20C AUX (BioM\u00e9rieux, Brussels, Belgium), MALDI TOF (Bruker Daltonik, Germany), and ITS gene region sequencing. <jats:italic>In vitro<\/jats:italic> susceptibility tests were performed using Sensititre YeastOne (TREK Diagnostic System, East Grinstead, UK). During the study period, 4,736 fungi were isolated from various clinical samples and, <jats:italic>S. clavata<\/jats:italic> was identified in eight patients with underlying diseases namely, pancreatic neoplasma, acute myeloid leukaemie, follicular lymphoma, cholelithiasis. Anidulafungin and micafungin minimum inhibitory concentration values were 1\u20132 and 1\u20134 mg\/L, respectively, while those of the azole group antifungals were much lower. This is the first study in Turkey reporting isolation, identification and antifungal susceptibilities of <jats:italic>S. clavata<\/jats:italic> from clinical specimens. Higher MIC values seen in some isolates suggest that continuous monitoring of sensitivity rates and observation of regional differences will thus be useful guides in determining infection control and antifungal use policies.<\/jats:p>","DOI":"10.1556\/030.2020.01301","type":"journal-article","created":{"date-parts":[[2020,12,5]],"date-time":"2020-12-05T03:07:07Z","timestamp":1607137627000},"page":"252-257","update-policy":"https:\/\/doi.org\/10.1556\/policypage.crossmark.crossref.1","source":"Crossref","is-referenced-by-count":1,"title":["Identification and antifungal susceptibility of Saprochaete clavata from invasive infections in Turkey"],"prefix":"10.1556","volume":"67","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1673-9101","authenticated-orcid":true,"given":"Esra","family":"\u00d6zkaya","sequence":"first","affiliation":[{"name":"1Department of Clinical Microbiology, Karadeniz Technical University School of Medicine, Trabzon, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u0130lknur","family":"Tosun","sequence":"additional","affiliation":[{"name":"1Department of Clinical Microbiology, Karadeniz Technical University School of Medicine, Trabzon, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"En\u0130s Fuat","family":"T\u00fcfek\u00e7\u0130","sequence":"additional","affiliation":[{"name":"2Department of Clinical Microbiology, Kastamonu University School of Medicine, Kastamonu, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Celal Kurtulu\u015f","family":"Buruk","sequence":"additional","affiliation":[{"name":"1Department of Clinical Microbiology, Karadeniz Technical University School of Medicine, Trabzon, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ne\u015fe","family":"Kakl\u0131kkaya","sequence":"additional","affiliation":[{"name":"1Department of Clinical Microbiology, Karadeniz Technical University School of Medicine, Trabzon, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Faruk","family":"Ayd\u0131n","sequence":"additional","affiliation":[{"name":"1Department of Clinical Microbiology, Karadeniz Technical University School of Medicine, Trabzon, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","reference":[{"volume-title":"Reference method for broth dilution antifungal susceptibility testing of yeasts","year":"2017","key":"ref71"},{"key":"ref81","doi-asserted-by":"crossref","first-page":"1100","DOI":"10.1111\/myc.12978","article-title":"Saprochaete clavata infections in patients undergoing treatment for haematological malignancies: a report of a monocentric outbreak and review of the literature","volume":"62","author":"Stanzani","year":"2019","journal-title":"Mycoses"},{"key":"ref111","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1111\/ejh.12303","article-title":"Disseminated Saprochaete capitata (formerly known as Geotrichum 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