{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T08:12:50Z","timestamp":1758960770596,"version":"3.40.5"},"reference-count":60,"publisher":"Akademiai Kiado Zrt.","issue":"1","content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":["AMicr"],"published-print":{"date-parts":[[2021,5,13]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Bartonella henselae<\/jats:italic> is the causative agent of cat scratch disease (CSD). In this study, we aimed to investigate the clinical data of patients with suspicion of CSD and delineate current epidemiological features.<\/jats:p><jats:p>A total of 785 patients with suspected CSD were included in the study. <jats:italic>B. henselae<\/jats:italic> IgM antibody was determined by indirect fluorescent antibody (IFA) test using a commercial kit (Euroimmun, Germany). Sex, age, clinical pre-diagnosis and animal contact information of the patients were obtained from hospital electronic database records.<\/jats:p><jats:p>Seventy-eight (9.9%) of 785 samples were seropositive. Out of 78 patients, 46 with animal contact data were further analyzed. Of these patients, 56% were male, and 41% were under 18 years of age. Seropositivity was more commonly observed in fall and winter. The most common finding was lymphadenitis (63%). Thirty-five patients (76%) had a previous history of animal contact (cat\/dog). Of the 46 seropositive patients, 78.3, 15.2, 4.4, and 2.1% had titers of 1:80, 1:160, 1:320, and 1:640, respectively.<\/jats:p><jats:p>Our study confirms that CSD is not rare in Turkey. Thus, it should always be considered in the differential diagnosis of patients presenting with lymphadenopathy in all age groups, particularly children. Questioning of cat exposure should never be neglected, especially in areas with intense population of stray cats, such as Istanbul.<\/jats:p>","DOI":"10.1556\/030.2021.01310","type":"journal-article","created":{"date-parts":[[2021,3,3]],"date-time":"2021-03-03T18:40:06Z","timestamp":1614796806000},"page":"14-19","update-policy":"https:\/\/doi.org\/10.1556\/policypage.crossmark.crossref.1","source":"Crossref","is-referenced-by-count":6,"title":["Bartonella henselae IgM seropositivity in both adult and pediatric patients with diverse clinical conditions in Turkey"],"prefix":"10.1556","volume":"68","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4788-0044","authenticated-orcid":true,"given":"Neslihan","family":"Ar\u0131c\u0131","sequence":"first","affiliation":[{"name":"1Haydarpasa Research and Training Hospital, Microbiology Laboratory, T.C. University of Health Sciences, Istanbul, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sebahat","family":"Aksaray","sequence":"additional","affiliation":[{"name":"2Department of Medical Microbiology, Faculty of Medicine Hamidiye, T.C. University of Health Sciences, Istanbul, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Handan","family":"Ankaral\u0131","sequence":"additional","affiliation":[{"name":"3Department of Bioistatistic, Faculty of Medicine, Medeniyet University, Istanbul, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","reference":[{"key":"ref291","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.mimet.2007.09.004","article-title":"The use of Bartonella henselae-specific age dependent IgG and IgM in diagnostic models to discriminate diseased from non-diseased in cat scratch disease serology","volume":"71","author":"Herremans","year":"2007","journal-title":"J Microbiol Methods"},{"key":"ref481","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1186\/1471-2334-10-121","article-title":"Seroprevalence of Bartonella in Eastern China and analysis of risk factors","volume":"10","author":"Sun","year":"2010","journal-title":"BMC Infect 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