{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T14:45:28Z","timestamp":1779201928150,"version":"3.51.4"},"reference-count":58,"publisher":"Akademiai Kiado Zrt.","content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":["AMicr"],"published-print":{"date-parts":[[2022,3,21]]},"abstract":"<jats:title>Abstract<\/jats:title>\n            <jats:p>\n               <jats:italic>Myroides<\/jats:italic> spp. are opportunistic environmental Gram-negative bacteria. These affect mostly immunocompromised hosts and generally lead to soft tissue, and urinary tract infections. Bacteremia most commonly develop secondary to soft tissue or catheter related infections and may lead rarely to mortality. <jats:italic>Myroides<\/jats:italic> spp. are generally suscetible to fluoroquinolones, piperacillin\/tazobactam, trimethoprim\/sulfamethoxazole, carbapenems or tetracyclines however, pan-resistant isolates and multiple resistance genes have been reported in clinical isolates of <jats:italic>Myroides<\/jats:italic> spp. We report a pan-resistant <jats:italic>Myroides odoratimimus<\/jats:italic> bacteremia in a patient with severe COVID-19 ending with fatality and in this context a review of reported <jats:italic>Myroides<\/jats:italic> bacteremias are also described.<\/jats:p>\n            <jats:p>In this study, a 64-year old male patient with history of coronary artery bypass was admitted to ICU with severe COVID-19 pneumonia accompanied by pneumomediastinum and pneumopericardium. Continous renal replacement therapy and extracorporeal membraneous-oxygenation were initiated due to acute renal failure and persistent hypercarbia\/hypoxia, respectively. Within four weeks of hospitalization various episodes of bacteremia developed and multiple antibiotics were used. On the 5<jats:sup>th<\/jats:sup> week of follow-up, acute phase reactants increased and empirical broad spectrum antibiotics were initiated. Blood culture revealed Gram-negative rods. The patient became hypotensive and despite maximum medical care he was lost due to cardiac arrest. <jats:italic>M. odoratimimus<\/jats:italic> was identified by MALDI-TOF and the bacterium was pan-resistant. According to Center for Genomic Epidemiology results the strain was identified as <jats:italic>M. odoratimimus<\/jats:italic> PR63039 and the genome analysis revealed antibiotic resistance genes associated with resistance to beta-lactams (<jats:italic>bla<\/jats:italic>\n               <jats:sub>OXA-347<\/jats:sub>, <jats:italic>bla<\/jats:italic>\n               <jats:sub>MUS-1<\/jats:sub>, <jats:italic>bla<\/jats:italic>\n               <jats:sub>EBR-1<\/jats:sub>), tetracyclines (<jats:italic>tetX<\/jats:italic>), sulfonamides (<jats:italic>sul2<\/jats:italic>), macrolides (<jats:italic>ereD<\/jats:italic>), (<jats:italic>ermF<\/jats:italic>).<\/jats:p>","DOI":"10.1556\/030.2022.01702","type":"journal-article","created":{"date-parts":[[2022,3,21]],"date-time":"2022-03-21T08:37:47Z","timestamp":1647851867000},"update-policy":"https:\/\/doi.org\/10.1556\/policypage.crossmark.crossref.1","source":"Crossref","is-referenced-by-count":15,"title":["A pan-resistant Myroides odoratimimus catheter-related bacteremia in a COVID-19 patient and review of the literature"],"prefix":"10.1556","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7454-7557","authenticated-orcid":true,"given":"Ahmet Furkan","family":"Kurt","sequence":"first","affiliation":[{"name":"Department of Infectious Diseases and Clinical Microbiology, Cerrahpasa School of Medicine, Istanbul University-Cerrahpasa, Istanbul, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9091-6087","authenticated-orcid":true,"given":"Bilgul","family":"Mete","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases and Clinical Microbiology, Cerrahpasa School of Medicine, Istanbul University-Cerrahpasa, Istanbul, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fatouma Moustapha","family":"Houssein","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases and Clinical Microbiology, Cerrahpasa School of Medicine, Istanbul University-Cerrahpasa, Istanbul, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yesim","family":"Tok","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology, Cerrahpasa School of Medicine, Istanbul University-Cerrahpasa, Istanbul, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mert Ahmet","family":"Kuskucu","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology, Cerrahpasa School of Medicine, Istanbul University-Cerrahpasa, Istanbul, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ebru","family":"Yucebag","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology, Cerrahpasa School of Medicine, Istanbul University-Cerrahpasa, Istanbul, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seval","family":"Urkmez","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Reanimation, Cerrahpasa School of Medicine, Istanbul University-Cerrahpasa, Istanbul, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fehmi","family":"Tabak","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases and Clinical Microbiology, Cerrahpasa School of Medicine, Istanbul University-Cerrahpasa, Istanbul, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gokhan","family":"Aygun","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology, Cerrahpasa School of Medicine, Istanbul University-Cerrahpasa, Istanbul, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","reference":[{"key":"ref441","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1007\/s15010-014-0626-0","article-title":"Fatal case of necrotizing fasciitis due to Myroides 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(Barc)"},{"key":"ref61","doi-asserted-by":"crossref","first-page":"e110","DOI":"10.14440\/jbm.2019.276","article-title":"A step-by-step beginner's protocol for whole genome sequencing of human bacterial pathogens","volume":"6","author":"Gautam","year":"2019","journal-title":"J Biol Methods"},{"key":"ref391","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1186\/s12859-018-2336-6","article-title":"Rapid and precise alignment of raw reads against redundant databases with KMA","volume":"19","author":"Clausen","year":"2018","journal-title":"BMC Bioinformatics"},{"key":"ref531","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1007\/s15010-010-0077-1","article-title":"Septic shock, pneumonia, and soft tissue infection due to Myroides odoratimimus: report of a case and review of Myroides infections","volume":"39","author":"Benedetti","year":"2011","journal-title":"Infection"},{"key":"ref541","first-page":"342","article-title":"Myroides odoratimimus bacteremia in a diabetic patient","volume":"28","author":"Endicott-Yazdani","year":"2015","journal-title":"Proc (Bayl Univ Med Cent)"},{"key":"ref521","first-page":"97","article-title":"Cellulitis due to Myroides odoratimimus in a patient with alcoholic cirrhosis","volume":"33","author":"Bachmeyer","year":"2008","journal-title":"Clin Exp Dermatol"},{"key":"ref111","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.idcr.2017.02.012","article-title":"Myroides bacteremia: a case report and concise review","volume":"8","author":"Beharrysingh","year":"2017","journal-title":"IDCases"},{"key":"ref221","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1007\/s15010-010-0077-1","article-title":"Septic shock, pneumonia, and soft tissue infection due to Myroides odoratimimus: report of a case and review of Myroides 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