{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T10:04:12Z","timestamp":1769508252709,"version":"3.49.0"},"reference-count":32,"publisher":"Akademiai Kiado Zrt.","issue":"3","license":[{"start":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T00:00:00Z","timestamp":1759968000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":["AMicr"],"published-print":{"date-parts":[[2025,10,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Herein we present a case of a 12-year-old child with acute symptoms (abdominal pain, fever). Preliminary\u00a0imaging suggested pyogenic liver abscess. Despite the broad-spectrum antibiotic therapy, which was started after hospital admission, no improvement was perceived. Rising eosinophilia and multiplex focal lesions detected by ultrasound and MRI forced serological investigation by which <jats:italic>Echinococcus granulosus s.l.<\/jats:italic> seropositivity was detected. Antihelminthic therapy was initiated and upon multidisciplinary consultation surgical intervention was performed with the removal of a cystic lesion which ruptured to the peritoneal cavity. Histopathological and parasitological analysis finally verified alveolar echinococcosis (AE) caused by <jats:italic>Echinococcus multilocularis.<\/jats:italic> As the evacuation of one lesion cannot be regarded as curative intervention in this form of echinococcosis, albendazole was administered continuously until patient's medical condition improved and no progression was detected during imaging follow-up. In Hungary both cystic and alveolar echinococcosis are present therefore differential diagnosis of these two forms can be a clinical challenge. Slow rate of progression, long lasting asymptomatic period and relatively low incidence of AE disease can explain that cases during childhood are rarely identified. After reviewing all relevant literature in this topic, we present here the first pediatric\u00a0AE case in Hungary.<\/jats:p>","DOI":"10.1556\/030.2025.02504","type":"journal-article","created":{"date-parts":[[2025,7,18]],"date-time":"2025-07-18T10:43:28Z","timestamp":1752835408000},"page":"280-286","update-policy":"https:\/\/doi.org\/10.1556\/policypage.crossmark.crossref.2","source":"Crossref","is-referenced-by-count":1,"title":["Acute peritoneal propagation of alveolar echinococcosis in a 12-year-old child"],"prefix":"10.1556","volume":"72","author":[{"given":"Kinga Karolina","family":"Kardics","sequence":"first","affiliation":[{"name":"Pediatric Center, MTA Center of Excellence, Semmelweis University, Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Krisztina","family":"Kalocsai","sequence":"additional","affiliation":[{"name":"Pediatric Center, MTA Center of Excellence, Semmelweis University, Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Attila","family":"K\u00e1lm\u00e1n","sequence":"additional","affiliation":[{"name":"Pediatric Center, MTA Center of Excellence, Semmelweis University, Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tam\u00e1s","family":"Benk\u0151","sequence":"additional","affiliation":[{"name":"Department of Surgery, Transplantation and Gastroenterology, Semmelweis University, Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T\u00edmea","family":"Seszt\u00e1k","sequence":"additional","affiliation":[{"name":"Pediatric Center, MTA Center of Excellence, Semmelweis University, Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Attila J\u00f3zsef","family":"Szab\u00f3","sequence":"additional","affiliation":[{"name":"Pediatric Center, MTA Center of Excellence, Semmelweis University, Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Judit","family":"Hal\u00e1sz","sequence":"additional","affiliation":[{"name":"Department of Pathology, Forensic and Insurance Medicine, Semmelweis University, Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erika","family":"Orosz","sequence":"additional","affiliation":[{"name":"National Reference Laboratory for Medical Parasitology, National Center for Public Health and Pharmacy, Budapest, Hungary"},{"name":"MikroMikoMed Ltd., Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00f3zsef","family":"Danka","sequence":"additional","affiliation":[{"name":"National Reference Laboratory for Medical Parasitology, National Center for Public Health and Pharmacy, Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tam\u00e1s","family":"Sr\u00e9ter","sequence":"additional","affiliation":[{"name":"National Reference Laboratory for Medical Parasitology, National Center for Public Health and Pharmacy, Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-7617-0573","authenticated-orcid":true,"given":"Bal\u00e1zs","family":"Dezs\u00e9nyi","sequence":"additional","affiliation":[{"name":"Department of Surgery, Transplantation and Gastroenterology, Semmelweis University, Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","reference":[{"key":"B1","series-title":"Advances in parasitology, Vol.95, echinococcus and echinococcosis part A","first-page":"214","article-title":"Ecology and life cycle patterns of echinococcus species","author":"Romig T","year":"2017","unstructured":"Romig T, Deplazes P, Jenkins D, Giraudoux P, Massolo A, Craig PS, et\u00a0al. 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Wilderness in the city, the urbanization of Echinococcus multilocularis. Trends Parasitol 2004; 20: 77\u201384."},{"key":"B4","series-title":"Trends Parasitol","first-page":"297","article-title":"Wilderness in the \u201ccity\u201d revisited different urbes shape transmission of Echinococcus multilocularis by altering predator and pray communities","volume":"31","author":"Liccioli S","year":"2015","unstructured":"Liccioli S, Giraudoux P, Deplazes P, Massolo A. Wilderness in the \u201ccity\u201d revisited different urbes shape transmission of Echinococcus multilocularis by altering predator and pray communities. Trends Parasitol 2015; 31: 297\u2013305."},{"key":"B5","series-title":"Curr Clin Microbiol Rep","first-page":"154","article-title":"Assassing the contamination of food and the environment with tenia and Echinococcus eggs and their zoonotic transmission","volume":"5","author":"Alvarez Rojas CA","year":"2018","unstructured":"Alvarez Rojas CA, Mathis A, Deplazes P. Assassing the contamination of food and the environment with tenia and Echinococcus eggs and their zoonotic transmission. Curr Clin Microbiol Rep 2018; 5: 154\u2013153."},{"key":"B6","series-title":"Plos Negl Trop Dis","article-title":"The economic evaluation of Cystic Echinococcosis control strategies focused on zoonotic hosts: a scoping review","volume":"15","author":"Widdicombe J","year":"2021","unstructured":"Widdicombe J, Basanez MG, Entezami M, Jackson D, Larrieu E, Prada JM. The economic evaluation of Cystic Echinococcosis control strategies focused on zoonotic hosts: a scoping review. 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Parasitol Int 2020; 80: 102214."},{"key":"B31","series-title":"Parasitol Res","first-page":"3019","article-title":"Prevalence and genetic characterization of Echinococcus spp. in cattle, sheep, and swine in Hungary","volume":"117","author":"D\u00e1n \u00c1","year":"2018","unstructured":"D\u00e1n \u00c1, R\u00f3nai Z, Sz\u00e9ll Z, Sr\u00e9ter T. Prevalence and genetic characterization of Echinococcus spp. in cattle, sheep, and swine in Hungary. Parasitol Res 2018; 117: 3019\u20133030."},{"key":"B32","series-title":"Infection","first-page":"477","article-title":"Human cystic echinococcosis in Hungary (2000-2014): a retrospective case series analysis from a single-center study","volume":"46","author":"Dezs\u00e9nyi B","year":"2018","unstructured":"Dezs\u00e9nyi B, Somor\u00e1cz \u00c1, Danka J, Kucsera I, Barth TFE, Casulli A. Human cystic echinococcosis in Hungary (2000-2014): a retrospective case series analysis from a single-center study. 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