{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T13:56:39Z","timestamp":1791381399233,"version":"4.3.3"},"reference-count":88,"publisher":"Akademiai Kiado Zrt.","issue":"3","content-domain":{"domain":["www.akjournals.com"],"crossmark-restriction":true},"short-container-title":["AMICR"],"published-print":{"date-parts":[[2026,10,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    <jats:italic>Candida auris<\/jats:italic>\n                    is an opportunistic yeast causing infections in vulnerable patients leading to high mortality ratio. The Centers for Disease Control and Prevention (CDC) has designated it as a pathogen of concern. The World Health Organization (WHO) has listed it in priority list of fungal pathogens.\n                    <jats:italic>C.\u00a0auris<\/jats:italic>\n                    has the ability to spread very fast inside the hospital environment and cause outbreaks worldwide. It has a very high affinity toward skin colonization, especially in the areas like axilla and groin. Based on whole genome sequencing it is classified into five clades. Each clade has different geographical distribution. Often\n                    <jats:italic>C. auris<\/jats:italic>\n                    gets misidentified as other species due to its phylogenetic similarity with\n                    <jats:italic>C.\u00a0heamulonii<\/jats:italic>\n                    . This can only be resolved by establishing diagnosis at molecular levels. Whole genome sequencing and polymerase chain reaction are some of the important molecular diagnostic methods for detection of\n                    <jats:italic>C. auris<\/jats:italic>\n                    . MALDI-TOF-MS is a culture based highly efficient method that is widely being used for\n                    <jats:italic>C. auris<\/jats:italic>\n                    identification. Treatment of\n                    <jats:italic>C. auris<\/jats:italic>\n                    infection depends on effective antifungal therapy, as multidrug resistance is quite common, the drug regime is decided after antifungal sensitivity testing. It is commonly treated with echinocandins and polyenes. Apart from the antifungal therapy it is also important to monitor the fungemia by performing blood cultures. A strict surveillance system can help prevent the disease. Timely screening of hospital personnel carrying the yeast can contain the spread of this organism. Newer antifungal agents are also required as the organism develops resistance very fast.\n                  <\/jats:p>","DOI":"10.1556\/030.2026.02993","type":"journal-article","created":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T07:28:13Z","timestamp":1785742093000},"page":"288-297","update-policy":"https:\/\/doi.org\/10.1556\/policypage.crossmark.crossref.2","source":"Crossref","is-referenced-by-count":0,"title":["Candida auris: An opportunistic fungal pathogen and a priority emergent threat"],"prefix":"10.1556","volume":"73","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9481-2939","authenticated-orcid":true,"given":"Shila Kumari","family":"Singh","sequence":"first","affiliation":[{"name":"Faculty of Allied and Healthcare Sciences, Assam down town University, Sankar Madhab Path, Gandhi Nagar, Panikhaiti, Guwahati, Assam, India, PIN-781026"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anantabotla","family":"Vamsimohan","sequence":"additional","affiliation":[{"name":"Delhi Skill and Entrepreneurship University, Dwarka campus, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"425","reference":[{"key":"B1","series-title":"Candida auris","article-title":"About C. auris","author":"CDC","year":"2024","unstructured":"CDC. About C. auris. Candida auris 2024. https:\/\/www.cdc.gov\/candida-auris\/about\/index.html."},{"key":"B2","series-title":"Candida auris","author":"Sikora A","year":"2023","unstructured":"Sikora A, Hashmi MF, Zahra F. Candida auris. Nih.gov. StatPearls Publishing; 2023. http:\/\/www.ncbi.nlm.nih.gov\/books\/NBK563297\/."},{"issue":"5","key":"B3","series-title":"Microorganisms","first-page":"927","article-title":"Candida auris outbreaks: current status and future perspectives","volume":"12","author":"De Gaetano S","year":"2024","unstructured":"De Gaetano S, Midiri A, Mancuso G, Avola MG, Biondo C. Candida auris outbreaks: current status and future perspectives. Microorganisms 2024; 12(5): 927."},{"key":"B4","series-title":"Med Sci Monit","first-page":"28","article-title":"Editorial: the World Health Organization (WHO) fungal priority pathogens list in response to emerging fungal pathogens during the COVID-19 pandemic","volume":"1","author":"Parums DV","year":"2022","unstructured":"Parums DV. Editorial: the World Health Organization (WHO) fungal priority pathogens list in response to emerging fungal pathogens during the COVID-19 pandemic. Med Sci Monit 2022; 1: 28."},{"issue":"5","key":"B5","series-title":"PLoS pathog","article-title":"Advances in the treatment of invasive fungal disease","volume":"19","author":"Zhang Z","year":"2023 4","unstructured":"Zhang Z, Bills GF, An Z. Advances in the treatment of invasive fungal disease. In: Chowdhary A, editor. PLoS pathog; 2023 4, vol 19(5)."},{"issue":"1","key":"B6","series-title":"Microbiol Immunol","first-page":"41","article-title":"Candida auris sp. nov., a novel ascomycetous yeast isolated from the external ear canal of an inpatient in a Japanese hospital","volume":"53","author":"Satoh K","year":"2009","unstructured":"Satoh K, Makimura K, Hasumi Y, Nishiyama Y, Uchida K, Yamaguchi H. Candida auris sp. nov., a novel ascomycetous yeast isolated from the external ear canal of an inpatient in a Japanese hospital. Microbiol Immunol 2009; 53(1): 41\u20134."},{"issue":"9","key":"B7","series-title":"J Clin Microbiol","first-page":"3139","article-title":"First three reported cases of nosocomial fungemia caused by Candida auris","volume":"49","author":"Lee WG","year":"2011","unstructured":"Lee WG, Shin JH, Uh Y, Kang MG, Kim SH, Park KH, et\u00a0al. First three reported cases of nosocomial fungemia caused by Candida auris. J Clin Microbiol 2011; 49(9): 3139\u201342."},{"issue":"37","key":"B8","series-title":"Eurosurveillance","first-page":"12","article-title":"Isolation of Candida auris from invasive and non-invasive samples of a patient suffering from vascular disease, Italy","volume":"24","author":"Crea F","year":"2019","unstructured":"Crea F, Codda G, Orsi A, Battaglini A, Giacobbe DR, Delfino E, et\u00a0al. Isolation of Candida auris from invasive and non-invasive samples of a patient suffering from vascular disease, Italy. Eurosurveillance 2019; 24(37): 12."},{"issue":"1","key":"B9","series-title":"Med Mycol","first-page":"98","article-title":"Biofilm formation and genotyping of Candida haemulonii, Candida pseudohaemulonii , and a proposed new species (Candida auris) isolates from Korea","volume":"49","author":"Oh BJ","year":"2011","unstructured":"Oh BJ, Shin JH, Kim MN, Sung H, Lee K, Joo MY, et\u00a0al. Biofilm formation and genotyping of Candida haemulonii, Candida pseudohaemulonii , and a proposed new species (Candida auris) isolates from Korea. Med Mycol 2011; 49(1): 98\u2013102."},{"issue":"1","key":"B10","series-title":"Med Mycol","first-page":"1","article-title":"Candida auris: The recent emergence of a multidrug-resistant fungal pathogen","volume":"57","author":"Forsberg K","year":"2019","unstructured":"Forsberg K, Woodworth K, Walters M, Berkow EL, Jackson B, Chiller T, et\u00a0al. Candida auris: The recent emergence of a multidrug-resistant fungal pathogen. Med Mycol 2019 Jan 1; 57(1): 1\u201312."},{"issue":"4","key":"B11","series-title":"J Hosp Infect","first-page":"363","article-title":"Controlling a possible outbreak of Candida auris infection: lessons learnt from multiple interventions","volume":"97","author":"Biswal M","year":"2019","unstructured":"Biswal M, Rudramurthy SM, Jain N, Shamanth AS, Sharma D, Jain K, et\u00a0al. Controlling a possible outbreak of Candida auris infection: lessons learnt from multiple interventions. J Hosp Infect 2019; 97(4): 363\u201370."},{"issue":"1","key":"B12","series-title":"Crit Care","first-page":"150","article-title":"The global challenge of Candida auris in the intensive care unit","volume":"23","author":"Cortegiani A","year":"2019","unstructured":"Cortegiani A, Misseri G, Giarratano A, Bassetti M, Eyre D. The global challenge of Candida auris in the intensive care unit. Crit Care 2019; 23(1): 150."},{"issue":"9","key":"B13","series-title":"Infect Control Hosp Epidemiol","first-page":"1107","article-title":"Environmental surfaces in healthcare facilities are a potential source for transmission of Candida auris and other Candida species","volume":"38","author":"Piedrahita CT","year":"2017","unstructured":"Piedrahita CT, Cadnum JL, Jencson AL, Shaikh AA, Ghannoum MA, Donskey CJ. 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