{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T13:43:58Z","timestamp":1778939038439,"version":"3.51.4"},"reference-count":0,"publisher":"Akademiai Kiado Zrt.","issue":"3","content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":["Acta Microbiologica et Immunologica Hungarica"],"published-print":{"date-parts":[[2015,9]]},"abstract":"<jats:p>Increasing resistance to drugs represents a serious problem in treatment of infections with <jats:italic>Helicobacter pylori<\/jats:italic>, providing cause of frequent therapeutic failures. Present study aimed at analysis of changes in resistance of <jats:italic>H. pylori<\/jats:italic> to antibiotics in West Poland within the recent 15 years. 108 strains of <jats:italic>H. pylori<\/jats:italic> were analysed, isolated from gastric mucosa of adult patients. Group 1 involved 66 strains isolated in years of 1998\/1999. Group 2 comprised 42 isolates obtained in years of 2013\/2014. Susceptibility to amoxicillin (AMX), clarithromycin (CL), tetracycline (TC) and metronidazole (MTZ) was determined by E-test (AB Biodisc). All strains on both studied groups were susceptible to AMX. In group 1 all strains proved to be susceptible to TC, while 9% and 36% of tested strains were resistant to CL and MTZ, respectively. By contrast, in group 2, 31% and 83% of strains were resistant to CL and MTZ, respectively. In parallel, 14% strains were found to be resistant to TC (according to EUCAST interpretations). In West Poland, within recent 15 years a dramatic increase was noted in <jats:italic>H. pylori<\/jats:italic> strains resistant to metronidazole. In parallel, a significant increase was noted in proportion of strains resistant to clarithromycin.<\/jats:p>","DOI":"10.1556\/030.62.2015.3.6","type":"journal-article","created":{"date-parts":[[2015,9,24]],"date-time":"2015-09-24T04:20:30Z","timestamp":1443068430000},"page":"287-293","update-policy":"https:\/\/doi.org\/10.1556\/policypage.crossmark.crossref.1","source":"Crossref","is-referenced-by-count":15,"title":["Evaluation of antimicrobial resistance of Helicobacter pylori in the last 15 years in West Poland"],"prefix":"10.1556","volume":"62","author":[{"given":"Tomasz M.","family":"Karpi\u0144ski","sequence":"first","affiliation":[{"name":"1Department of Medical Microbiology, Pozna\u0144 University of Medical Sciences, Wieniawskiego Str. 3, 61-712 Pozna\u0144, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ewa","family":"Andrzejewska","sequence":"additional","affiliation":[{"name":"1Department of Medical Microbiology, Pozna\u0144 University of Medical Sciences, Wieniawskiego Str. 3, 61-712 Pozna\u0144, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Piotr","family":"Eder","sequence":"additional","affiliation":[{"name":"2Department of Gastroenterology, Human Nutrition and Internal Diseases, Pozna\u0144 University of Medical Sciences, Przybyszewskiego Str. 49, 60-355 Pozna\u0144, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Krzysztof","family":"Linke","sequence":"additional","affiliation":[{"name":"2Department of Gastroenterology, Human Nutrition and Internal Diseases, Pozna\u0144 University of Medical Sciences, Przybyszewskiego Str. 49, 60-355 Pozna\u0144, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrzej","family":"Szkaradkiewicz","sequence":"additional","affiliation":[{"name":"1Department of Medical Microbiology, Pozna\u0144 University of Medical Sciences, Wieniawskiego Str. 3, 61-712 Pozna\u0144, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","container-title":["Acta Microbiologica et Immunologica Hungarica"],"original-title":[],"link":[{"URL":"https:\/\/akjournals.com\/view\/journals\/030\/62\/3\/article-p287.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/akjournals.com\/downloadpdf\/journals\/030\/62\/3\/article-p287.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T11:51:16Z","timestamp":1614599476000},"score":1,"resource":{"primary":{"URL":"https:\/\/akjournals.com\/view\/journals\/030\/62\/3\/article-p287.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,9]]},"references-count":0,"journal-issue":{"issue":"3"},"URL":"https:\/\/doi.org\/10.1556\/030.62.2015.3.6","relation":{},"ISSN":["1217-8950","1588-2640"],"issn-type":[{"value":"1217-8950","type":"print"},{"value":"1588-2640","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,9]]}}}