{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T03:15:40Z","timestamp":1787022940938,"version":"build-2736575974"},"reference-count":0,"publisher":"Akademiai Kiado Zrt.","issue":"1","content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":["Acta Microbiologica et Immunologica Hungarica"],"published-print":{"date-parts":[[2017,2,16]]},"abstract":"<jats:p>\n                    Shigellosis is a considerable infectious disease with high morbidity and mortality among children worldwide. In this survey the prevalence of four important virulence genes including\n                    <jats:italic>ial<\/jats:italic>\n                    ,\n                    <jats:italic>ipaH<\/jats:italic>\n                    ,\n                    <jats:italic>set1A<\/jats:italic>\n                    , and\n                    <jats:italic>set1B<\/jats:italic>\n                    were investigated among\n                    <jats:italic>Shigella<\/jats:italic>\n                    strains and the related gene profiles identified in the present investigation, stool specimens were collected from children who were referred to two hospitals in Tehran, Iran. The samples were collected during 3 years (2008\u20132010) from children who were suspected to shigellosis.\n                    <jats:italic>Shigella<\/jats:italic>\n                    spp. were identified throughout microbiological and serological tests and then subjected to PCR for virulotyping.\n                    <jats:italic>Shigella sonnei<\/jats:italic>\n                    was ranking first (65.5%) followed by\n                    <jats:italic>Shigella flexneri<\/jats:italic>\n                    (25.9%),\n                    <jats:italic>Shigella boydii<\/jats:italic>\n                    (6.9%), and\n                    <jats:italic>Shigella dysenteriae<\/jats:italic>\n                    (1.7%). The\n                    <jats:italic>ial<\/jats:italic>\n                    gene was the most frequent virulence gene among isolated bacterial strains and was followed by\n                    <jats:italic>ipaH<\/jats:italic>\n                    ,\n                    <jats:italic>set1B<\/jats:italic>\n                    , and\n                    <jats:italic>set1A<\/jats:italic>\n                    .\n                    <jats:italic>S. flexneri<\/jats:italic>\n                    possessed all of the studied virulence genes (\n                    <jats:italic>ial<\/jats:italic>\n                    65.51%,\n                    <jats:italic>ipaH<\/jats:italic>\n                    58.62%,\n                    <jats:italic>set1A<\/jats:italic>\n                    12.07%, and set1B 22.41%). Moreover, the pattern of virulence gene profiles including\n                    <jats:italic>ial<\/jats:italic>\n                    ,\n                    <jats:italic>ial<\/jats:italic>\n                    \u2013\n                    <jats:italic>ipaH<\/jats:italic>\n                    ,\n                    <jats:italic>ial\u2013ipaH\u2013set1B<\/jats:italic>\n                    , and\n                    <jats:italic>ial\u2013ipaH\u2013set1B\u2013set1A<\/jats:italic>\n                    was identified for isolated\n                    <jats:italic>Shigella<\/jats:italic>\n                    spp. strains. The pattern of virulence genes is changed in isolated strains of\n                    <jats:italic>Shigella<\/jats:italic>\n                    in this study. So, the\n                    <jats:italic>ial<\/jats:italic>\n                    gene is placed first and the\n                    <jats:italic>ipaH<\/jats:italic>\n                    in second.\n                  <\/jats:p>","DOI":"10.1556\/030.64.2017.007","type":"journal-article","created":{"date-parts":[[2017,2,20]],"date-time":"2017-02-20T06:43:59Z","timestamp":1487573039000},"page":"71-80","update-policy":"https:\/\/doi.org\/10.1556\/policypage.crossmark.crossref.1","source":"Crossref","is-referenced-by-count":13,"title":["Virulotyping of Shigella spp. isolated from pediatric patients in Tehran, Iran"],"prefix":"10.1556","volume":"64","author":[{"given":"Reza","family":"Ranjbar","sequence":"first","affiliation":[{"name":"1 Molecular Biology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masomeh","family":"Bolandian","sequence":"additional","affiliation":[{"name":"1 Molecular Biology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Payam","family":"Behzadi","sequence":"additional","affiliation":[{"name":"2 Department of Microbiology, College of Basic Sciences, Shahr-e-Qods Branch, Islamic Azad University, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"425","container-title":["Acta Microbiologica et Immunologica Hungarica"],"original-title":[],"link":[{"URL":"https:\/\/akjournals.com\/view\/journals\/030\/64\/1\/article-p71.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/akjournals.com\/downloadpdf\/journals\/030\/64\/1\/article-p71.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T06:51:37Z","timestamp":1614581497000},"score":1,"resource":{"primary":{"URL":"https:\/\/akjournals.com\/view\/journals\/030\/64\/1\/article-p71.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,2,16]]},"references-count":0,"journal-issue":{"issue":"1"},"URL":"https:\/\/doi.org\/10.1556\/030.64.2017.007","relation":{},"ISSN":["1217-8950","1588-2640"],"issn-type":[{"value":"1217-8950","type":"print"},{"value":"1588-2640","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,2,16]]}}}