{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T11:27:56Z","timestamp":1790681276955,"version":"4.1.0"},"reference-count":64,"publisher":"Akademiai Kiado Zrt.","issue":"3","content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":["AMicr"],"published-print":{"date-parts":[[2018,7,18]]},"abstract":"The aim of this study was to investigate the prevalence of carbapenem-resistant Klebsiella pneumoniae<\/jats:italic> (CRKP) and the most common types of carbapenemases, metallo-beta-lactamases (MBLs), and extended-spectrum beta-lactamases (ESBLs) among CRKP isolates in a tertiary hospital in Isfahan, Iran. Eighty non-repetitive clinical isolates of K. pneumoniae<\/jats:italic> were obtained from different clinical specimens. Antibiotic resistance pattern of isolates was determined by disk diffusion method and production of carbapenemases and MBLs was confirmed using modified Hodge test and E-test, respectively. Molecular detection of the antibiotic resistance genes was performed using PCR. Fifty-one (63.8%) isolates have decreased susceptibility to carbapenems, of which 46 (90.2%) isolates were as carbapenemase producer and four (7.8%) isolates were positive for MBLs, phenotypically. The results of PCR showed that the prevalence of bla<\/jats:italic>OXA-48<\/jats:sub>, bla<\/jats:italic>NDM<\/jats:sub>, bla<\/jats:italic>SHV<\/jats:sub>, bla<\/jats:italic>CTX-M<\/jats:sub>, and bla<\/jats:italic>TEM<\/jats:sub> genes among CRKP isolates were 90.2%, 15.7%, 98%, 96.1%, and 90.2%, respectively. No isolates carrying the bla<\/jats:italic>KPC<\/jats:sub>, bla<\/jats:italic>GES<\/jats:sub>, bla<\/jats:italic>IMI<\/jats:sub>, bla<\/jats:italic>VIM<\/jats:sub>, and bla<\/jats:italic>IMP<\/jats:sub> genes were detected. This study showed that the production of OXA-48 is one of the main mechanisms of resistance to carbapenems in CRKP isolates in Isfahan. In addition, the dissemination of NDM-producing CRKP isolates is a potential risk for the health care system of this area in the near future.<\/jats:p>","DOI":"10.1556\/030.65.2018.034","type":"journal-article","created":{"date-parts":[[2018,7,19]],"date-time":"2018-07-19T12:36:21Z","timestamp":1532003781000},"page":"335-344","update-policy":"https:\/\/doi.org\/10.1556\/policypage.crossmark.crossref.1","source":"Crossref","is-referenced-by-count":19,"title":["The emergence of blaOXA-48 and blaNDM among ESBL-producing Klebsiella pneumoniae in clinical isolates of a tertiary hospital in Iran"],"prefix":"10.1556","volume":"65","author":[{"given":"Mehdi","family":"Moghadampour","sequence":"first","affiliation":[{"name":"1 Department of Microbiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aliakbar","family":"Rezaei","sequence":"additional","affiliation":[{"name":"1 Department of Microbiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jamshid","family":"Faghri","sequence":"additional","affiliation":[{"name":"1 Department of Microbiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"425","reference":[{"key":"ref251","doi-asserted-by":"crossref","first-page":"2763","DOI":"10.1093\/jac\/dkr382","article-title":"Introduction of OXA-48-producing Enterobacteriaceae to Israeli hospitals by medical tourism","volume":"66","author":"Adler","year":"2011","journal-title":"J Antimicrob Chemother"},{"key":"ref111","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1016\/j.ijfoodmicro.2008.03.005","article-title":"PCR detection of Klebsiella pneumoniae in infant formula based on 16S-23S internal transcribed spacer","volume":"125","author":"Liu","year":"2008","journal-title":"Int J Food Microbiol"},{"key":"ref151","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1128\/CMR.00001-07","article-title":"Carbapenemases: The versatile beta-lactamases","volume":"20","author":"Queenan","year":"2007","journal-title":"Clin Microbiol Rev"},{"key":"ref71","doi-asserted-by":"crossref","first-page":"1597","DOI":"10.1093\/jac\/dks121","article-title":"OXA-48-like carbapenemases: The phantom menace","volume":"67","author":"Poirel","year":"2012","journal-title":"J Antimicrob Chemother"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"e57091","DOI":"10.1371\/journal.pone.0057091","article-title":"Genotypic analysis of Klebsiella pneumoniae isolates in a Beijing Hospital reveals high genetic diversity and clonal population structure of drug-resistant isolates","volume":"8","author":"Wang","year":"2013","journal-title":"PLoS One"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"492","DOI":"10.2307\/30141189","article-title":"Evidence of interhospital transmission of extended-spectrum beta-lactam-resistant Klebsiella pneumoniae in the United States, 1986 to 1993. The National Nosocomial Infections Surveillance System","volume":"18","author":"Monnet","year":"1997","journal-title":"Infect Control Hosp Epidemiol"},{"key":"ref301","first-page":"347","article-title":"Prevalence of blaCTX-M gene among extended-spectrum \u03b2-lactamases producing Klebsiella pneumoniae clinical isolates in Iran: A meta-analysis","volume":"43","author":"Eskandari-Nasab","year":"2018","journal-title":"Iran J Med Sci"},{"key":"ref381","doi-asserted-by":"crossref","first-page":"ofv050","DOI":"10.1093\/ofid\/ofv050","article-title":"Treatment options for carbapenem-resistant Enterobacteriaceae infections","volume":"2","author":"Morrill","year":"2015","journal-title":"Open Forum Infect Dis"},{"key":"ref421","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1179\/1973947815Y.0000000063","article-title":"Current methods for the identification of carbapenemases","volume":"28","author":"Bialvaei","year":"2016","journal-title":"J Chemother"},{"key":"ref641","first-page":"205","article-title":"Detection of New Delhi metallo-beta-lactamase-1 (NDM-1) in carbapenem-resistant Klebsiella pneumoniae isolated from a university hospital in Iran","volume":"19","author":"Fazeli","year":"2015","journal-title":"Hippokratia"},{"key":"ref81","first-page":"61","article-title":"Determination of antibiotic resistance pattern and prevalence of OXA-type carbapenemases among Acinetobacter baumannii clinical isolates from inpatients in Isfahan, Central Iran","volume":"26","author":"Rezaei","year":"2018","journal-title":"Infez Med"},{"key":"ref221","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1111\/j.1469-0691.2012.03823.x","article-title":"Interventional strategies and current clinical experience with carbapenemase-producing Gram-negative bacteria","volume":"18","author":"Akova","year":"2012","journal-title":"Clin Microbiol Infect"},{"key":"ref561","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1179\/1973947815Y.0000000008","article-title":"Prevalence of CTX-M-8 and CTX-M-15 type extended-spectrum beta-lactamases between Klebsiella pneumoniae spp. isolated from Zahedan, Southeast Iran","volume":"28","author":"Shahraki-Zahedani","year":"2016","journal-title":"J Chemother"},{"key":"ref521","first-page":"1031","article-title":"Detection of New Delhi metallo-beta-lactamase-1-producing Klebsiella pneumoniae at a general hospital in Thailand","volume":"46","author":"Preechachuawong","year":"2015","journal-title":"Southeast Asian J Trop Med Public Health"},{"key":"ref541","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1111\/j.1469-0691.2011.03570.x","article-title":"Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: An international expert proposal for interim standard definitions for acquired resistance","volume":"18","author":"Magiorakos","year":"2012","journal-title":"Clin Microbiol Infect"},{"key":"ref131","doi-asserted-by":"crossref","first-page":"e22260","DOI":"10.5812\/ircmj.22260","article-title":"Prevalence of CTX-M-Type and PER extended-spectrum beta-lactamases among Klebsiella spp. isolated from clinical specimens in the teaching hospital of Kashan, Iran","volume":"18","author":"Amiri","year":"2016","journal-title":"Iran Red Crescent Med J"},{"key":"ref331","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1017\/S0950268811000781","article-title":"Wide dissemination of extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli and Klebsiella spp. in acute care and rehabilitation hospitals","volume":"140","author":"Kohlenberg","year":"2012","journal-title":"Epidemiol Infect"},{"key":"ref181","doi-asserted-by":"crossref","first-page":"2091","DOI":"10.1093\/jac\/dku105","article-title":"The Balkan region: NDM-1-producing Klebsiella pneumoniae ST11 clonal strain causing outbreaks in Greece","volume":"69","author":"Voulgari","year":"2014","journal-title":"J Antimicrob Chemother"},{"key":"ref401","doi-asserted-by":"crossref","first-page":"1597","DOI":"10.1093\/jac\/dks121","article-title":"OXA-48-like carbapenemases: The phantom menace","volume":"67","author":"Poirel","year":"2012","journal-title":"J Antimicrob Chemother"},{"key":"ref191","first-page":"1031","article-title":"Detection of New Delhi metallo-beta-lactamase-1-producing Klebsiella pneumoniae at a general hospital in Thailand","volume":"46","author":"Preechachuawong","year":"2015","journal-title":"Southeast Asian J Trop Med Public Health"},{"key":"ref341","doi-asserted-by":"crossref","first-page":"492","DOI":"10.2307\/30141189","article-title":"Evidence of interhospital transmission of extended-spectrum beta-lactam-resistant Klebsiella pneumoniae in the United States, 1986 to 1993. The National Nosocomial Infections Surveillance System","volume":"18","author":"Monnet","year":"1997","journal-title":"Infect Control Hosp Epidemiol"},{"key":"ref531","doi-asserted-by":"crossref","first-page":"3724","DOI":"10.1128\/AAC.47.12.3724-3732.2003","article-title":"Prevalence and molecular epidemiology of CTX-M extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae in Russian hospitals","volume":"47","author":"Edelstein","year":"2003","journal-title":"Antimicrob Agents Chemother"},{"key":"ref371","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1586\/eri.11.28","article-title":"Status report on carbapenemases: Challenges and prospects","volume":"9","author":"Patel","year":"2011","journal-title":"Expert Rev Anti Infect Ther"},{"key":"ref511","doi-asserted-by":"crossref","first-page":"2091","DOI":"10.1093\/jac\/dku105","article-title":"The Balkan region: NDM-1-producing Klebsiella pneumoniae ST11 clonal strain causing outbreaks in Greece","volume":"69","author":"Voulgari","year":"2014","journal-title":"J Antimicrob Chemother"},{"key":"ref571","doi-asserted-by":"crossref","first-page":"305784","DOI":"10.1155\/2014\/305784","article-title":"Epidemiology of carbapenemase-producing Enterobacteriaceae and Acinetobacter baumannii in Mediterranean countries","volume":"2014","author":"Djahmi","year":"2014","journal-title":"Biomed Res Int"},{"key":"ref61","doi-asserted-by":"crossref","first-page":"841951","DOI":"10.1155\/2014\/841951","article-title":"Carbapenemases in gram-negative bacteria: Laboratory detection and clinical significance","volume":"2014","author":"Bedenic","year":"2014","journal-title":"Biomed Res Int"},{"key":"ref481","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1128\/CMR.00001-07","article-title":"Carbapenemases: The versatile beta-lactamases","volume":"20","author":"Queenan","year":"2007","journal-title":"Clin Microbiol Rev"},{"key":"ref311","first-page":"205","article-title":"Detection of New Delhi metallo-beta-lactamase-1 (NDM-1) in carbapenem-resistant Klebsiella pneumoniae isolated from a university hospital in Iran","volume":"19","author":"Fazeli","year":"2015","journal-title":"Hippokratia"},{"key":"ref581","doi-asserted-by":"crossref","first-page":"2763","DOI":"10.1093\/jac\/dkr382","article-title":"Introduction of OXA-48-producing Enterobacteriaceae to Israeli hospitals by medical tourism","volume":"66","author":"Adler","year":"2011","journal-title":"J Antimicrob Chemother"},{"key":"ref611","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1016\/j.jcma.2017.08.015","article-title":"Emerge of blaNDM-1 and blaOXA-48-like harboring carbapenem-resistant Klebsiella pneumoniae isolates from hospitalized patients in southwestern Iran","volume":"81","author":"Hosseinzadeh","year":"2017","journal-title":"J Chin Med Assoc"},{"key":"ref91","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1179\/1973947815Y.0000000063","article-title":"Current methods for the identification of carbapenemases","volume":"28","author":"Bialvaei","year":"2016","journal-title":"J Chemother"},{"key":"ref01","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1017\/S0950268811000781","article-title":"Wide dissemination of extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli and Klebsiella spp. in acute care and rehabilitation hospitals","volume":"140","author":"Kohlenberg","year":"2012","journal-title":"Epidemiol Infect"},{"key":"ref201","doi-asserted-by":"crossref","first-page":"3724","DOI":"10.1128\/AAC.47.12.3724-3732.2003","article-title":"Prevalence and molecular epidemiology of CTX-M extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae in Russian hospitals","volume":"47","author":"Edelstein","year":"2003","journal-title":"Antimicrob Agents Chemother"},{"key":"ref51","doi-asserted-by":"crossref","first-page":"ofv050","DOI":"10.1093\/ofid\/ofv050","article-title":"Treatment options for carbapenem-resistant Enterobacteriaceae infections","volume":"2","author":"Morrill","year":"2015","journal-title":"Open Forum Infect Dis"},{"key":"ref351","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1111\/j.1469-0691.2011.03478.x","article-title":"Outcome of carbapenem resistant Klebsiella pneumoniae bloodstream infections","volume":"18","author":"Ben-David","year":"2012","journal-title":"Clin Microbiol Infect"},{"key":"ref621","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.1093\/jac\/dky081","article-title":"Molecular epidemiology of NDM-1- and OXA-48-producing Klebsiella pneumoniae in an Iranian hospital: Clonal dissemination of ST11 and ST893","volume":"73","author":"Solgi","year":"2018","journal-title":"J Antimicrob Chemother"},{"key":"ref231","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1179\/1973947815Y.0000000008","article-title":"Prevalence of CTX-M-8 and CTX-M-15 type extended-spectrum beta-lactamases between Klebsiella pneumoniae spp. isolated from Zahedan, Southeast Iran","volume":"28","author":"Shahraki-Zahedani","year":"2016","journal-title":"J Chemother"},{"key":"ref501","doi-asserted-by":"crossref","first-page":"4114","DOI":"10.1128\/AAC.00778-06","article-title":"Analysis of antibiotic resistance genes in multidrug-resistant Acinetobacter sp. isolates from military and civilian patients treated at the Walter Reed Army Medical Center","volume":"50","author":"Hujer","year":"2006","journal-title":"Antimicrob Agents Chemother"},{"key":"ref461","doi-asserted-by":"crossref","first-page":"e22260","DOI":"10.5812\/ircmj.22260","article-title":"Prevalence of CTX-M-Type and PER extended-spectrum beta-lactamases among Klebsiella spp. isolated from clinical specimens in the teaching hospital of Kashan, Iran","volume":"18","author":"Amiri","year":"2016","journal-title":"Iran Red Crescent Med J"},{"key":"ref241","doi-asserted-by":"crossref","first-page":"305784","DOI":"10.1155\/2014\/305784","article-title":"Epidemiology of carbapenemase-producing Enterobacteriaceae and Acinetobacter baumannii in Mediterranean countries","volume":"2014","author":"Djahmi","year":"2014","journal-title":"Biomed Res Int"},{"key":"ref471","doi-asserted-by":"crossref","first-page":"2879","DOI":"10.1128\/JCM.00661-08","article-title":"Rapid detection of blaKPC carbapenemase genes by real-time PCR","volume":"46","author":"Hindiyeh","year":"2008","journal-title":"J Clin Microbiol"},{"key":"ref161","doi-asserted-by":"crossref","first-page":"e95181","DOI":"10.1371\/journal.pone.0095181","article-title":"Phenotypic and molecular characterization of multidrug resistant Klebsiella pneumoniae isolated from a university teaching hospital, China","volume":"9","author":"Du","year":"2014","journal-title":"PLoS One"},{"key":"ref261","first-page":"Doc07","article-title":"First report of OXA-48-producing Klebsiella pneumoniae strains in Iran","volume":"9","author":"Azimi","year":"2014","journal-title":"GMS Hygiene Infect Control"},{"key":"ref321","doi-asserted-by":"crossref","first-page":"41","DOI":"10.4103\/2277-9175.204594","article-title":"Prevalence of acquired carbapenemase genes in Klebsiella pneumoniae by multiplex PCR in Isfahan","volume":"6","author":"Khorvash","year":"2017","journal-title":"Adv Biomed Res"},{"key":"ref141","doi-asserted-by":"crossref","first-page":"2879","DOI":"10.1128\/JCM.00661-08","article-title":"Rapid detection of blaKPC carbapenemase genes by real-time PCR","volume":"46","author":"Hindiyeh","year":"2008","journal-title":"J Clin Microbiol"},{"key":"ref441","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1016\/j.ijfoodmicro.2008.03.005","article-title":"PCR detection of Klebsiella pneumoniae in infant formula based on 16S-23S internal transcribed spacer","volume":"125","author":"Liu","year":"2008","journal-title":"Int J Food Microbiol"},{"key":"ref281","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1016\/j.jcma.2017.08.015","article-title":"Emerge of blaNDM-1 and blaOXA-48-like harboring carbapenem-resistant Klebsiella pneumoniae isolates from hospitalized patients in southwestern Iran","volume":"81","author":"Hosseinzadeh","year":"2017","journal-title":"J Chin Med Assoc"},{"key":"ref361","doi-asserted-by":"crossref","first-page":"e57091","DOI":"10.1371\/journal.pone.0057091","article-title":"Genotypic analysis of Klebsiella pneumoniae isolates in a Beijing Hospital reveals high genetic diversity and clonal population structure of drug-resistant isolates","volume":"8","author":"Wang","year":"2013","journal-title":"PLoS One"},{"key":"ref491","doi-asserted-by":"crossref","first-page":"e95181","DOI":"10.1371\/journal.pone.0095181","article-title":"Phenotypic and molecular characterization of multidrug resistant Klebsiella pneumoniae isolated from a university teaching hospital, China","volume":"9","author":"Du","year":"2014","journal-title":"PLoS One"},{"key":"ref431","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1128\/CMR.11.4.589","article-title":"Klebsiella spp. as nosocomial pathogens: Epidemiology, taxonomy, typing methods, and pathogenicity factors","volume":"11","author":"Podschun","year":"1998","journal-title":"Clin Microbiol Rev"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1111\/j.1469-0691.2011.03478.x","article-title":"Outcome of carbapenem resistant Klebsiella pneumoniae bloodstream infections","volume":"18","author":"Ben-David","year":"2012","journal-title":"Clin Microbiol Infect"},{"key":"ref171","doi-asserted-by":"crossref","first-page":"4114","DOI":"10.1128\/AAC.00778-06","article-title":"Analysis of antibiotic resistance genes in multidrug-resistant Acinetobacter sp. isolates from military and civilian patients treated at the Walter Reed Army Medical Center","volume":"50","author":"Hujer","year":"2006","journal-title":"Antimicrob Agents Chemother"},{"key":"ref211","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1111\/j.1469-0691.2011.03570.x","article-title":"Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: An international expert proposal for interim standard definitions for acquired resistance","volume":"18","author":"Magiorakos","year":"2012","journal-title":"Clin Microbiol Infect"},{"key":"ref651","doi-asserted-by":"crossref","first-page":"41","DOI":"10.4103\/2277-9175.204594","article-title":"Prevalence of acquired carbapenemase genes in Klebsiella pneumoniae by multiplex PCR in Isfahan","volume":"6","author":"Khorvash","year":"2017","journal-title":"Adv Biomed Res"},{"key":"ref601","doi-asserted-by":"crossref","first-page":"726179","DOI":"10.1155\/2014\/726179","article-title":"Detection of beta-lactamases and outer membrane porins among Klebsiella pneumoniae strains isolated in Iran","volume":"2014","author":"Hashemi","year":"2014","journal-title":"Scientifica"},{"key":"ref551","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1111\/j.1469-0691.2012.03823.x","article-title":"Interventional strategies and current clinical experience with carbapenemase-producing Gram-negative bacteria","volume":"18","author":"Akova","year":"2012","journal-title":"Clin Microbiol Infect"},{"key":"ref271","doi-asserted-by":"crossref","first-page":"726179","DOI":"10.1155\/2014\/726179","article-title":"Detection of beta-lactamases and outer membrane porins among Klebsiella pneumoniae strains isolated in Iran","volume":"2014","author":"Hashemi","year":"2014","journal-title":"Scientifica"},{"key":"ref631","first-page":"347","article-title":"Prevalence of blaCTX-M gene among extended-spectrum \u03b2-lactamases producing Klebsiella pneumoniae clinical isolates in Iran: A meta-analysis","volume":"43","author":"Eskandari-Nasab","year":"2018","journal-title":"Iran J Med Sci"},{"key":"ref101","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1128\/CMR.11.4.589","article-title":"Klebsiella spp. as nosocomial pathogens: Epidemiology, taxonomy, typing methods, and pathogenicity factors","volume":"11","author":"Podschun","year":"1998","journal-title":"Clin Microbiol Rev"},{"key":"ref591","first-page":"Doc07","article-title":"First report of OXA-48-producing Klebsiella pneumoniae strains in Iran","volume":"9","author":"Azimi","year":"2014","journal-title":"GMS Hygiene Infect Control"},{"key":"ref411","first-page":"61","article-title":"Determination of antibiotic resistance pattern and prevalence of OXA-type carbapenemases among Acinetobacter baumannii clinical isolates from inpatients in Isfahan, Central Iran","volume":"26","author":"Rezaei","year":"2018","journal-title":"Infez Med"},{"key":"ref391","doi-asserted-by":"crossref","first-page":"841951","DOI":"10.1155\/2014\/841951","article-title":"Carbapenemases in gram-negative bacteria: Laboratory detection and clinical significance","volume":"2014","author":"Bedenic","year":"2014","journal-title":"Biomed Res Int"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1586\/eri.11.28","article-title":"Status report on carbapenemases: Challenges and prospects","volume":"9","author":"Patel","year":"2011","journal-title":"Expert Rev Anti Infect Ther"},{"key":"ref291","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.1093\/jac\/dky081","article-title":"Molecular epidemiology of NDM-1- and OXA-48-producing Klebsiella pneumoniae in an Iranian hospital: Clonal dissemination of ST11 and ST893","volume":"73","author":"Solgi","year":"2018","journal-title":"J Antimicrob Chemother"}],"container-title":["Acta Microbiologica et Immunologica Hungarica"],"original-title":[],"link":[{"URL":"https:\/\/www.akademiai.com\/doi\/full-xml\/10.1556\/030.65.2018.034","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/akjournals.com\/view\/journals\/030\/65\/3\/article-p335.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/akjournals.com\/downloadpdf\/journals\/030\/65\/3\/article-p335.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,3,3]],"date-time":"2021-03-03T14:42:44Z","timestamp":1614782564000},"score":1,"resource":{"primary":{"URL":"https:\/\/akjournals.com\/view\/journals\/030\/65\/3\/article-p335.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7,18]]},"references-count":64,"journal-issue":{"issue":"3"},"URL":"https:\/\/doi.org\/10.1556\/030.65.2018.034","relation":{},"ISSN":["1217-8950","1588-2640"],"issn-type":[{"value":"1217-8950","type":"print"},{"value":"1588-2640","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,7,18]]}}}