{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T22:01:36Z","timestamp":1759010496821},"reference-count":34,"publisher":"Akademiai Kiado Zrt.","issue":"4","content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":["AMicr"],"published-print":{"date-parts":[[2019,7,9]]},"abstract":"<jats:p>This study performed an epidemiological survey of <jats:italic>Neisseria meningitidis<\/jats:italic> strains isolated from patients and from asymptomatic carriers. Altogether, 74 <jats:italic>N. meningitidis<\/jats:italic> strains (46 invasive and 28 non-invasive) were isolated between February 2011 and May 2018 in different regions of the Republic of Belarus. Serogenotyping was carried out by real-time PCR. Minimum inhibitory concentrations (MICs) of antibiotics were determined by broth microdilution and results were interpreted in accordance with EUCAST. The serogroups of <jats:italic>N.\u00a0meningitidis<\/jats:italic> were determined as follows: serogroup B \u2013 65%, C \u2013 11%, W \u2013 9%, A \u2013 5%, Y \u2013 4%, and Z and NG \u2013 3% each. The MIC<jats:sub>50<\/jats:sub> and MIC<jats:sub>90<\/jats:sub> for benzylpenicillin (0.032\/0.064\u20130.125\u00a0mg\/L), ampicillin (0.032\/0.125\u00a0mg\/L), amoxicillin (0.125\/0.25\u00a0mg\/L), cefotaxime (0.016\/0.016\u00a0mg\/L), ceftriaxone (0.002\/0.016\u00a0mg\/L), ciprofloxacin (0.004\/0.008\u00a0mg\/L), chloramphenicol (1\/1\u00a0mg\/L), meropenem (0.008\/0.008\u20130.016\u00a0mg\/L), tetracycline (0.25\/0.5\u00a0mg\/L), and rifampicin (0.016\/0.25\u00a0mg\/L) were established. Strains with intermediate susceptibility for benzylpenicillin (12.3%), ampicillin (6.8%), and amoxicillin (24.7%) have been identified. In this study, we report the first rifampicin-resistant <jats:italic>N.\u00a0meningitidis<\/jats:italic> in Belarus.<\/jats:p>","DOI":"10.1556\/030.66.2019.018","type":"journal-article","created":{"date-parts":[[2019,7,29]],"date-time":"2019-07-29T13:24:03Z","timestamp":1564406643000},"page":"443-457","update-policy":"http:\/\/dx.doi.org\/10.1556\/policypage.crossmark.crossref.1","source":"Crossref","is-referenced-by-count":2,"title":["Serogroup diversity and antibiotic susceptibility of Neisseria meningitidis: Meningococcus infection monitoring in Belarus"],"prefix":"10.1556","volume":"66","author":[{"given":"Hanna N.","family":"Kharkhal","sequence":"first","affiliation":[{"name":"1 Laboratory of Clinical and Experimental Microbiology, The Republican Research and Practical Center for Epidemiology and Microbiology, Minsk, Republic of Belarus"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leonid P.","family":"Titov","sequence":"additional","affiliation":[{"name":"1 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