{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T05:09:25Z","timestamp":1747199365489,"version":"3.40.5"},"reference-count":75,"publisher":"Akademiai Kiado Zrt.","issue":"2","content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":["MaSeb"],"published-print":{"date-parts":[[2022,6,20]]},"abstract":"\n Bevezet\u00e9s<\/jats:title>\n Az el\u00fcls\u0151 mediastinum leggyakoribb daganata, a\u00a0thymoma\u00a0videotorakoszk\u00f3pos elt\u00e1vol\u00edt\u00e1sa\u00a0m\u00e1ra\u00a0vil\u00e1gszerte elterjed\u0151ben l\u00e9v\u0151, de sok tekintetben m\u00e9g vitatott m\u0171t\u00e9ti elj\u00e1r\u00e1ss\u00e1 v\u00e1lt. Az egyoldali megk\u00f6zel\u00edt\u00e9ssel v\u00e9gzett m\u0171t\u00e9teink korai \u00e9s k\u00e9s\u0151i eredm\u00e9nyeit elemezz\u00fck k\u00e9t magyar mellkasseb\u00e9szeti centrum 17 \u00e9ves adatai alapj\u00e1n.<\/jats:p>\n <\/jats:sec>\n \n M\u00f3dszer<\/jats:title>\n A\u00a0thymoma\u00a0anat\u00f3miai helyzet\u00e9t\u0151l f\u00fcgg\u0151en jobb vagy bal oldal fel\u0151l, 2 vagy 3 intercostalis porton kereszt\u00fcl, ultrahangos v\u00e1g\u00f3eszk\u00f6z \u00e9s elektrokauter seg\u00edts\u00e9g\u00e9vel thymomectomi\u00e1t \u00e9s thymectomi\u00e1t v\u00e9gezt\u00fcnk Masaoka\u2013Koga\u00a0I\u2013II\u2013III. st\u00e1diumban. Nemzetk\u00f6zi standardokat alkalmazva\u00a0elemezt\u00fck a\u00a0perioperat\u00edv sz\u00f6v\u0151dm\u00e9nyeket, a\u00a0k\u00f6z\u00e9pt\u00e1v\u00fa onkol\u00f3giai \u00e9s a\u00a0myastheni\u00e1s klinikai eredm\u00e9nyeket.<\/jats:p>\n <\/jats:sec>\n \n Eredm\u00e9nyek<\/jats:title>\n 54 beteg (23 f\u00e9rfi, 31 n\u0151), \u00e9letkori \u00e1tlag 58 (26\u201379) \u00e9v, k\u00f6z\u00fcl\u00fck 23\u00a0myasthenia\u00a0gravis betegs\u00e9ggel. Konverzi\u00f3: 7\/61 (11,5%). \u00c1tlagos m\u0171t\u00e9ti id\u0151: 84 (39\u2013150) perc. \u00c1tlagos \u00e1pol\u00e1si id\u0151: 5,5 (3\u201319) nap. Thymoma\u00a0\u00e1tlagos m\u00e9rete: 46 (18\u201390) mm. Sz\u00f6vettan: A\u00a0(2), AB (19), B1\/2\/3 (11\/11\/1), vegyes B (10). Reszekci\u00f3s vonal: R0\/1\/2 (41\/12\/1). Masaoka\u2013Koga-st\u00e1dium: I. (17), IIA. (29), IIB. (1), III. (7). 25 thymomectomia, 29 thymectomia. H\u00e9t betegn\u00e9l kiterjeszt\u00e9s pericardiumra\u00a0(2), t\u00fcd\u0151re (4), rekeszidegre (6), vena\u00a0anonym\u00e1ra\u00a0(1). 30 napon t\u00fali k\u00f3rh\u00e1zi hal\u00e1loz\u00e1s 1 eset (1,85%). Morbidit\u00e1s: 11\/54 (20,4%). \u00c1tlagos k\u00f6vet\u00e9si id\u0151 62,6 (5\u2013198) h\u00f3nap. A\u00a0myastheni\u00e1s betegcsoportban a\u00a0m\u0171t\u00e9t effektivit\u00e1sa\u00a018\/21 (85,7%), ezen bel\u00fcl a\u00a0komplett remisszi\u00f3 5\/21 (23,8%). Postthymectomi\u00e1s myasthenia\u00a0gravis\u00a02\/31 (6,5%) esetben alakult ki. Az \u00e1ltal\u00e1nos 5 \u00e9ves t\u00fal\u00e9l\u00e9s 100% volt, a\u00a0daganatmentes 5 \u00e9ves t\u00fal\u00e9l\u00e9s 96%-nak bizonyult.<\/jats:p>\n <\/jats:sec>\n \n K\u00f6vetkeztet\u00e9sek<\/jats:title>\n A\u00a0korai eredm\u00e9nyekben a\u00a0thymomectomia\u00a0magasabb ar\u00e1nya\u00a0\u00e9s a\u00a0magas konverzi\u00f3s r\u00e1ta, valamint az alacsonyabb R0-ar\u00e1ny \u00f6sszef\u00fcgghet a\u00a0seb\u00e9szek szeml\u00e9let\u00e9vel, tanul\u00f3idej\u00e9vel \u00e9s az egyoldali m\u0171t\u00e9ti m\u00f3dszer korl\u00e1taival. A\u00a0k\u00e9s\u0151i eredm\u00e9nyek a\u00a0k\u00f6vet\u00e9si id\u0151 n\u00f6veked\u00e9s\u00e9vel re\u00e1lisabb\u00e1 \u00e9s \u00f6sszehasonl\u00edthat\u00f3bb\u00e1 v\u00e1lhatnak. Az egyoldali VATS-technika\u00a0helyett a\u00a0kedvez\u0151bb vizu\u00e1lis jellemz\u0151k miatt \u00e1tt\u00e9rt\u00fcnk a\u00a0subxyphoid VATS-thymectomi\u00e1k v\u00e9gz\u00e9s\u00e9re.<\/jats:p>\n <\/jats:sec>","DOI":"10.1556\/1046.2022.20001","type":"journal-article","created":{"date-parts":[[2022,6,22]],"date-time":"2022-06-22T15:51:08Z","timestamp":1655913068000},"page":"79-95","update-policy":"https:\/\/doi.org\/10.1556\/policypage.crossmark.crossref.2","source":"Crossref","is-referenced-by-count":0,"title":["Az unilateralis videoassziszt\u00e1lt torakoszk\u00f3pos thymomaelt\u00e1vol\u00edt\u00e1s javallata, korai \u00e9s k\u00f6z\u00e9pt\u00e1v\u00fa eredm\u00e9nyei"],"prefix":"10.1556","volume":"75","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0600-8161","authenticated-orcid":true,"given":"J\u00f3zsef","family":"Kas","sequence":"first","affiliation":[{"name":"Orsz\u00e1gos Kor\u00e1nyi Pulmonol\u00f3giai Int\u00e9zet (f\u0151igazgat\u00f3: dr. 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Am Soc Clin Oncol Educ Book \n 2014; e367\u2013e373."},{"issue":"6","key":"B9","series-title":"Eur J Cardiothorac Surg","first-page":"1545","article-title":"State of the art: diagnostic tools and innovative therapies for treatment of advanced thymoma and thymic carcinoma","volume":"49","author":"Ried \n M","year":"2016","unstructured":"Ried \n M\n , \n Marx \n A\n , \n G\u00f6tz \n A\n , \n Hamer \n O\n , \n Schalke \n B\n , \n Hofmann \n HS\n \n . State of the art: diagnostic tools and innovative therapies for treatment of advanced thymoma and thymic carcinoma. Eur J Cardiothorac Surg \n 2016; 49(6): 1545\u20131552."},{"issue":"Suppl 2","key":"B10","series-title":"J Thorac Dis","first-page":"S228","article-title":"Management of thymic tumors: a European perspective","volume":"6","author":"Ruffini \n E","year":"2014","unstructured":"Ruffini \n E\n , \n Venuta \n F\n \n . Management of thymic tumors: a European perspective. J Thorac Dis \n 2014; 6(Suppl 2): S228\u2013S237."},{"issue":"1","key":"B11","series-title":"Ann Thorac Surg","first-page":"142","article-title":"Thoracoscopic resection of an anterior mediastinal tumor","volume":"54","author":"Landreneau \n RJ","year":"1992","unstructured":"Landreneau \n RJ\n , \n Dowling \n RD\n , \n Castillo \n WM\n , \n Ferson \n PF\n \n . Thoracoscopic resection of an anterior mediastinal tumor. Ann Thorac Surg \n 1992; 54(1): 142\u2013144."},{"issue":"2","key":"B12","series-title":"Ann Thorac Surg","first-page":"562","article-title":"Thoracoscopic thymoma resection","volume":"55","author":"Acuff \n TE","year":"1993","unstructured":"Acuff \n TE\n , \n Mack \n MJ\n , \n Ryan \n WH\n , \n Bowman \n RT\n , \n Douthit \n MB\n \n . Thoracoscopic thymoma resection. Ann Thorac Surg \n 1993; 55(2): 562\u2013563."},{"key":"B13","series-title":"Chest Surg Clin N Am","first-page":"185","article-title":"Thymoma. The use of minimally invasive resection techniques","volume":"4","author":"Kaiser \n LR","year":"1994","unstructured":"Kaiser \n LR\n \n . Thymoma. The use of minimally invasive resection techniques. Chest Surg Clin N Am \n 1994; 4: 185\u2013194."},{"issue":"4","key":"B14","series-title":"Ann Thorac Surg","first-page":"1210","article-title":"Adjuvant pneumomediastinum in thoracoscopic thymectomy for myasthenia gravis","volume":"62","author":"Mineo \n TC","year":"1996","unstructured":"Mineo \n TC\n , \n Pompeo \n E\n , \n Ambrogi \n V\n , \n Sabato \n AF\n , \n Bernardi \n G\n , \n Casciani \n CU\n \n . Adjuvant pneumomediastinum in thoracoscopic thymectomy for myasthenia gravis. 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Video-assisted extended thymectomy in patients with thymoma by lifting the sternum: is it safe? \n Ann Thorac Surg \n 2004; 77(5): 1878; author reply."},{"issue":"2","key":"B20","series-title":"Thymectomy Chest","first-page":"578","article-title":"Video-assisted thoracoscopic surgery","volume":"110","author":"Yellin \n A","year":"1996","unstructured":"Yellin \n A\n \n . Video-assisted thoracoscopic surgery. Thymectomy Chest \n 1996; 110(2): 578\u2013579."},{"issue":"1","key":"B21","series-title":"J Thorac Oncol","first-page":"129","article-title":"Determinants of complete resection of thymoma by minimally invasive and open thymectomy: analysis of an International Registry","volume":"12","author":"Burt \n BM","year":"2017","unstructured":"Burt \n BM\n , \n Yao \n X\n , \n Shrager \n J\n , \n Antonicelli \n A\n , \n Padda \n S\n , \n Reiss \n J\n , et al.\n \n Determinants of complete resection of thymoma by minimally invasive and open thymectomy: analysis of an International Registry. J Thorac Oncol \n 2017; 12(1): 129\u2013136."},{"issue":"1","key":"B22","series-title":"J Thorac Oncol","first-page":"30","article-title":"Minimally invasive versus open thymectomy for thymic malignancies: systematic review and meta-analysis","volume":"11","author":"Friedant \n AJ","year":"2016","unstructured":"Friedant \n AJ\n , \n Handorf \n EA\n , \n Su \n S\n , \n Scott \n WJ\n \n . Minimally invasive versus open thymectomy for thymic malignancies: systematic review and meta-analysis. J Thorac Oncol \n 2016; 11(1): 30\u201338."},{"issue":"1","key":"B23","series-title":"Ann Cardiothorac Surg","first-page":"1","article-title":"Minimally invasive versus open thymectomy: a systematic review of surgical techniques, patient demographics, and perioperative outcomes","volume":"5","author":"Hess \n NR","year":"2016","unstructured":"Hess \n NR\n , \n Sarkaria \n IS\n , \n Pennathur \n A\n , \n Levy \n RM\n , \n Christie \n NA\n , \n Luketich \n JD\n \n . Minimally invasive versus open thymectomy: a systematic review of surgical techniques, patient demographics, and perioperative outcomes. Ann Cardiothorac Surg \n 2016; 5(1): 1\u20139."},{"issue":"6","key":"B24","series-title":"Interact Cardiovasc Thorac Surg","first-page":"765","article-title":"Thymectomy for thymoma and myasthenia gravis. A survey of current surgical practice in thymic disease amongst EACTS members","volume":"14","author":"Lucchi \n M","year":"2012","unstructured":"Lucchi \n M\n , \n Van Schil \n P\n , \n Schmid \n R\n , \n Rea \n F\n , \n Melfi \n F\n , \n Athanassiadi \n K\n , et al. ; EACTS Thymic Working Group\n . Thymectomy for thymoma and myasthenia gravis. A survey of current surgical practice in thymic disease amongst EACTS members. 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Eur J Cardiothorac Surg \n 2014; 45(6): e187\u2013e193."},{"issue":"3","key":"B31","series-title":"J Thorac Cardiovasc Surg","first-page":"694","article-title":"Comparison of surgical techniques for early-stage thymoma: feasibility of minimally invasive thymectomy and comparison with open resection","volume":"141","author":"Pennathur \n A","year":"2011","unstructured":"Pennathur \n A\n , \n Qureshi \n I\n , \n Schuchert \n MJ\n , \n Dhupar \n R\n , \n Ferson \n PF\n , \n Gooding \n WE\n , et al.\n \n Comparison of surgical techniques for early-stage thymoma: feasibility of minimally invasive thymectomy and comparison with open resection. 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Eur J Surg Oncol \n 2016; 42(11): 1720\u20131728."},{"issue":"5","key":"B33","series-title":"J Thorac Cardiovasc Surg","first-page":"1599","article-title":"Surgical techniques for early-stage thymoma: video-assisted thoracoscopic thymectomy versus transsternal thymectomy","volume":"147","author":"Ye \n B","year":"2014","unstructured":"Ye \n B\n , \n Tantai \n JC\n , \n Ge \n XX\n , \n Li \n W\n , \n Feng \n J\n , \n Cheng \n M\n , et al.\n \n Surgical techniques for early-stage thymoma: video-assisted thoracoscopic thymectomy versus transsternal thymectomy. J Thorac Cardiovasc Surg \n 2014; 147(5): 1599\u20131603."},{"issue":"7","key":"B34","series-title":"J Thorac Oncol","first-page":"911","article-title":"Lung cancer disease site group of cancer care ontario's program in evidence-based care. 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Videothoracoscopos m\u00f3don, a jobb mell\u00fcreg fel\u0151l elv\u00e9gzett csecsem\u0151mirigy-elt\u00e1vol\u00edt\u00e1s \u2013 \u00faj m\u0171t\u00e9ti elj\u00e1r\u00e1s klinik\u00e1nk gyakorlat\u00e1ban. Magy Seb \n 2011; 64(4): 202\u2013206."},{"issue":"6","key":"B38","series-title":"Ann Cardiothorac Surg","first-page":"535","article-title":"Standardized definitions and policies of minimally invasive thymoma resection","volume":"4","author":"Toker \n A","year":"2015","unstructured":"Toker \n A\n \n . Standardized definitions and policies of minimally invasive thymoma resection. Ann Cardiothorac Surg \n 2015; 4(6): 535\u2013539."},{"issue":"Suppl 14","key":"B39","series-title":"J Thorac Dis","first-page":"S1666","article-title":"Members of the Chinese Alliance for Research in Thymomas. Minimally invasive surgery in thymic malignances: the new standard of care","volume":"10","author":"Zhang \n X","year":"2018","unstructured":"Zhang \n X\n , \n Gu \n Z\n , \n Fang \n W\n \n ; Members of the Chinese Alliance for Research in Thymomas. Minimally invasive surgery in thymic malignances: the new standard of care. J Thorac Dis \n 2018; 10(Suppl 14): S1666\u2013S1670."},{"key":"B40","series-title":"J Vis Surg","first-page":"99","article-title":"Definitions and standard indications of minimally-invasive techniques in thymic surgery","volume":"3","author":"Zieli\u0144ski \n M","year":"2017","unstructured":"Zieli\u0144ski \n M\n \n . Definitions and standard indications of minimally-invasive techniques in thymic surgery. 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Eur J Cardiothorac Surg \n 2021; https:\/\/doi.org\/10.1093\/ejcts\/ezab224."}],"container-title":["Magyar Seb\u00e9szet"],"original-title":[],"link":[{"URL":"https:\/\/akjournals.com\/view\/journals\/1046\/75\/2\/article-p79.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/akjournals.com\/downloadpdf\/journals\/1046\/75\/2\/article-p79.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/akjournals.com\/downloadpdf\/journals\/1046\/75\/2\/article-p79.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,21]],"date-time":"2023-02-21T11:03:59Z","timestamp":1676977439000},"score":1,"resource":{"primary":{"URL":"https:\/\/akjournals.com\/view\/journals\/1046\/75\/2\/article-p79.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6,20]]},"references-count":75,"journal-issue":{"issue":"2"},"URL":"https:\/\/doi.org\/10.1556\/1046.2022.20001","relation":{},"ISSN":["0025-0295","1789-4301"],"issn-type":[{"type":"print","value":"0025-0295"},{"type":"electronic","value":"1789-4301"}],"subject":[],"published":{"date-parts":[[2022,6,20]]}}}