{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T05:09:29Z","timestamp":1747199369146,"version":"3.40.5"},"reference-count":10,"publisher":"Akademiai Kiado Zrt.","issue":"4","content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":["MaSeb"],"published-print":{"date-parts":[[2022,12,14]]},"abstract":"<jats:sec><jats:title>Esetismertet\u00e9s<\/jats:title><jats:p>Progressz\u00edv gyomor\u00fcr\u00fcl\u00e9si zavar miatt v\u00e9gezt\u00fcnk m\u0171t\u00e9tet egy hatvan\u00f6t \u00e9ves n\u0151betegn\u00e9l. A colon transversumot infiltr\u00e1l\u00f3 irreszek\u00e1bilis gyomordaganatot \u00e9s peritone\u00e1lis karcin\u00f3zist \u00e9szlelt\u00fcnk. Palliat\u00edv gasztro-jejunoszt\u00f3mi\u00e1t \u00e9s ileo-descendoszt\u00f3mi\u00e1t helyezt\u00fcnk fel. A\u00a0klinikum, az endoszk\u00f3pia \u2013 linitis plastica \u2013, a m\u0171t\u00e9ti k\u00e9p \u00e9s az intraoperat\u00edv hisztol\u00f3gia gyomor shigillocellularis karcin\u00f3m\u00e1t v\u00e9lem\u00e9nyezett. Palliat\u00edv onkol\u00f3giai kezel\u00e9se alatt \u00e1llapota stagn\u00e1lt. A h\u00e1rom \u00e9vvel a m\u0171t\u00e9t ut\u00e1n kialakult recid\u00edv multiplex b\u0151r\u00e1tt\u00e9tek \u00e9s a jobb eml\u0151 k\u00fcls\u0151-fels\u0151 negyed\u00e9ben \u00e9szlelt daganat sz\u00f6vettani hormonreceptor-pozit\u00edv, hum\u00e1n epiderm\u00e1lis n\u00f6veked\u00e9si faktor receptor-2 negat\u00edv lobul\u00e1ris eml\u0151karcin\u00f3m\u00e1t igazolt. A kor\u00e1bbi m\u0171t\u00e9ti minta sz\u00f6vettani rev\u00edzi\u00f3ja meger\u0151s\u00edtette az ut\u00f3bbi diagn\u00f3zist. Ezt k\u00f6vet\u0151en palliat\u00edv hormonkezel\u00e9s hat\u00e1s\u00e1ra a tumoros folyamat csaknem komplett radiol\u00f3giai regresszi\u00f3t mutatott. A beteg panasz- \u00e9s t\u00fcnetmentes a kezdeti hasi panaszokat k\u00f6vet\u0151 hat \u00e9vvel.<\/jats:p><\/jats:sec><jats:sec><jats:title>Megbesz\u00e9l\u00e9s<\/jats:title><jats:p>Az eml\u0151 rosszindulat\u00fa daganatainak mintegy tizede lobul\u00e1ris karcin\u00f3ma. Az eml\u0151r\u00e1k t\u00f6bbi t\u00edpus\u00e1t\u00f3l elt\u00e9r\u0151en gyakrabban multicentrikus, bilater\u00e1lis, okkult \u00e9s metasztatiz\u00e1l sav\u00f3s h\u00e1rty\u00e1kra, has\u0171ri, kismedencei zsigerekbe. Eset\u00fcnk illusztr\u00e1lja, hogy az onkol\u00f3giai kezel\u00e9s fejl\u0151d\u00e9s\u00e9vel a palli\u00e1ci\u00f3 \u00faj \u00e9rtelmet nyer. Az\u00a0eml\u0151r\u00e1kos betegek n\u00f6vekv\u0151 t\u00fal\u00e9l\u00e9se miatt v\u00e1rhat\u00f3an a jelenleg ritka eml\u0151r\u00e1k-eredet\u0171 has\u0171ri \u00e1tt\u00e9tek sz\u00e1ma is n\u00f6vekszik. El\u0151rehaladott has\u00fcregi tumoros folyamatok eset\u00e9n is n\u00e9lk\u00fcl\u00f6zhetetlen a\u00a0hisztol\u00f3giai meger\u0151s\u00edt\u00e9s, k\u00fcl\u00f6n\u00f6sen a szokatlan k\u00f3rlefoly\u00e1s eset\u00e9n. Interdiszciplin\u00e1ris egy\u00fcttm\u0171k\u00f6d\u00e9s, onkoteamd\u00f6nt\u00e9sek k\u00edn\u00e1lnak csak tov\u00e1bbi javul\u00e1st az eml\u0151r\u00e1k diagnosztik\u00e1j\u00e1ban \u00e9s ter\u00e1pi\u00e1j\u00e1ban.<\/jats:p><\/jats:sec>","DOI":"10.1556\/1046.2022.40003","type":"journal-article","created":{"date-parts":[[2022,12,14]],"date-time":"2022-12-14T10:54:26Z","timestamp":1671015266000},"page":"265-269","update-policy":"https:\/\/doi.org\/10.1556\/policypage.crossmark.crossref.1","source":"Crossref","is-referenced-by-count":0,"title":["Eml\u0151r\u00e1k has\u00fcregi \u00e1tt\u00e9tei \u2013 Egy szokatlan entit\u00e1s klinikopatol\u00f3giai jellemz\u0151i"],"prefix":"10.1556","volume":"75","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5294-296X","authenticated-orcid":true,"given":"Andr\u00e1s","family":"Drozgyik","sequence":"first","affiliation":[{"name":"Petz Alad\u00e1r Egyetemi Oktat\u00f3 K\u00f3rh\u00e1z, Seb\u00e9szeti Oszt\u00e1ly, Gy\u0151r, Magyarorsz\u00e1g"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F. 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