{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T01:27:26Z","timestamp":1769822846196,"version":"3.49.0"},"reference-count":75,"publisher":"Akademiai Kiado Zrt.","issue":"1","license":[{"start":{"date-parts":[[2023,5,2]],"date-time":"2023-05-02T00:00:00Z","timestamp":1682985600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":["MaSeb"],"published-print":{"date-parts":[[2023,5,2]]},"abstract":"<jats:sec><jats:title>\u00d6sszefoglal\u00e1s<\/jats:title><jats:p>A melanoma seb\u00e9szete az elm\u00falt \u00e9vekben jelent\u0151sen \u00e1talakult. A nagy radikalit\u00e1s\u00fa, sok sz\u00f6v\u0151dm\u00e9nnyel j\u00e1r\u00f3 m\u0171t\u00e9teket, melyek mellett a teljes \u00e9s betegs\u00e9gmentes t\u00fal\u00e9l\u00e9s is alacsony maradt, fokozatosan felv\u00e1ltott\u00e1k a kisebb radikalit\u00e1s\u00fa m\u0171t\u00e9tek. Az \u00faj sziszt\u00e9m\u00e1s kezel\u00e9sek (c\u00e9lzott \u00e9s immuno-onkol\u00f3giai) adjuv\u00e1ns indik\u00e1ci\u00f3ban t\u00f6rt\u00e9n\u0151 bevezet\u00e9s\u00e9vel bizonyos m\u0171t\u00e9tek, mint az elekt\u00edv blokkdisszekci\u00f3k, ma m\u00e1r kiszorultak a seb\u00e9szi kezel\u00e9sekb\u0151l \u00e9s a seb\u00e9szet szerepe is \u00e1t\u00e9rt\u00e9kel\u0151d\u00f6tt. V\u00e1ltozott a prim\u00e9r tumor elt\u00e1vol\u00edt\u00e1s seb\u00e9szete, a reexc\u00edzi\u00f3 kivitelez\u00e9se, \u0151rszemnyirokcsom\u00f3 biopszia \u00e9s nyirokr\u00e9gi\u00f3k seb\u00e9szete, a b\u0151r \u00e9s t\u00e1voli \u00e1tt\u00e9tek seb\u00e9szeti ell\u00e1t\u00e1sa. Jelen \u00f6sszefoglal\u00f3 k\u00f6zlem\u00e9nyben a szerz\u0151k a nemzetk\u00f6zi irodalom \u00e9s saj\u00e1t gyakorlatuk alapj\u00e1n ny\u00fajtanak \u00e1ttekint\u00e9st a melanoma malignum jelenleg elfogadott seb\u00e9szeti ter\u00e1pi\u00e1j\u00e1r\u00f3l.<\/jats:p><\/jats:sec>","DOI":"10.1556\/1046.2023.10007","type":"journal-article","created":{"date-parts":[[2023,5,2]],"date-time":"2023-05-02T15:24:00Z","timestamp":1683041040000},"page":"39-47","update-policy":"https:\/\/doi.org\/10.1556\/policypage.crossmark.crossref.2","source":"Crossref","is-referenced-by-count":2,"title":["A melanoma malignum seb\u00e9szeti ell\u00e1t\u00e1sa \u2013 Elv\u00e1rhat\u00f3 standardok"],"prefix":"10.1556","volume":"76","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-8417-7432","authenticated-orcid":true,"given":"Zsolt","family":"K\u00e1d\u00e1r","sequence":"first","affiliation":[{"name":"P\u00e9csi Tudom\u00e1nyegyetem, Klinikai K\u00f6zpont, B\u0151r-, Nemik\u00f3rtani \u00e9s Onkodermatol\u00f3giai Klinika, P\u00e9cs, Magyarorsz\u00e1g"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zsuzsanna","family":"Lengyel","sequence":"additional","affiliation":[{"name":"P\u00e9csi Tudom\u00e1nyegyetem, Klinikai K\u00f6zpont, B\u0151r-, Nemik\u00f3rtani \u00e9s Onkodermatol\u00f3giai Klinika, P\u00e9cs, Magyarorsz\u00e1g"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rolland","family":"Gyulai","sequence":"additional","affiliation":[{"name":"P\u00e9csi Tudom\u00e1nyegyetem, Klinikai K\u00f6zpont, B\u0151r-, Nemik\u00f3rtani \u00e9s Onkodermatol\u00f3giai Klinika, P\u00e9cs, Magyarorsz\u00e1g"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","reference":[{"key":"B1","series-title":"Eur J Cancer","first-page":"236","article-title":"European consensus-based interdisciplinary guideline for melanoma, Part 1: diagnostics: Update 2022","volume":"170","author":"Garbe C","year":"2022","unstructured":"Garbe C, et al. 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