{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,1,4]],"date-time":"2024-01-04T00:05:39Z","timestamp":1704326739537},"reference-count":0,"publisher":"Akademiai Kiado Zrt.","issue":"3","content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":["MaSeb"],"published-print":{"date-parts":[[2019,9]]},"abstract":"<jats:title>Absztrakt: <\/jats:title>\n        <jats:p>\n          <jats:italic>Bevezet\u00e9s:<\/jats:italic> Alfred Blalock 80 \u00e9ve k\u00f6z\u00f6lt els\u0151 m\u0171t\u00e9te \u00f3ta a\n                    thymectomia a myasthenia gravis kezel\u00e9s\u00e9nek fontos r\u00e9sz\u00e9v\u00e9 v\u00e1lt. A k\u00fclf\u00f6ld\u00f6n m\u00e1r\n                    elfogadott t\u00f6bbf\u00e9le m\u0171t\u00e9ti elj\u00e1r\u00e1s ellen\u00e9re itthon 2006-ig a szegycsonti\n                    felt\u00e1r\u00e1s szinte kiz\u00e1r\u00f3lagos m\u00f3dszer volt a csecsem\u0151mirigy elt\u00e1vol\u00edt\u00e1s\u00e1ban.\n                    K\u00f6zlem\u00e9ny\u00fcnkben ennek a m\u00f3dszernek a k\u00f6zvetlen seb\u00e9szi k\u00f6vetkezm\u00e9nyeit,\n                    sz\u00f6v\u0151dm\u00e9nyeit elemezz\u00fck. <jats:italic>M\u00f3dszerek:<\/jats:italic> A Budai M\u00c1V K\u00f3rh\u00e1z\n                    Seb\u00e9szeti Oszt\u00e1ly\u00e1n 34 \u00e9v alatt 1002 transsternalis thymectomia t\u00f6rt\u00e9nt\n                    myasthenia gravis (MG) diagn\u00f3zis\u00fa betegeken. A m\u0171t\u00e9teket neurol\u00f3giai javallatra\n                    v\u00e9gezt\u00fck el, alapos kivizsg\u00e1l\u00e1s \u00e9s ideggy\u00f3gy\u00e1szati-belgy\u00f3gy\u00e1szati el\u0151k\u00e9sz\u00edt\u00e9s\n                    ut\u00e1n. A thymom\u00e1val t\u00e1rsult betegs\u00e9gben a thymus \u00e9s a tumor elt\u00e1vol\u00edt\u00e1sa kett\u0151s\n                    indik\u00e1ci\u00f3j\u00fa volt. A 34 \u00e9v alatt egyar\u00e1nt jelent\u0151sen m\u00f3dosult a neurol\u00f3giai\n                    javallat \u00e9s az el\u0151k\u00e9sz\u00edt\u00e9s, a perioperat\u00edv kezel\u00e9s \u00e9s a m\u0171t\u00e9ti technika is. Az\n                    eredm\u00e9nyeket a legjellemz\u0151bb m\u0171t\u00e9ti technika (egyszer\u0171 \u00e9s kiterjesztett\n                    thymectomia) alapj\u00e1n k\u00e9t korszakra tagolva, a thymom\u00e1s \u00e9s a reoper\u00e1ci\u00f3n \u00e1tesett\n                    betegek adatait pedig elk\u00fcl\u00f6n\u00edtve jelen\u00edtj\u00fck meg, els\u0151sorban a l\u00e9gz\u00e9ssel\n                    \u00f6sszef\u00fcgg\u0151 sz\u00f6v\u0151dm\u00e9nyekre koncentr\u00e1lva. <jats:italic>Eredm\u00e9nyek:<\/jats:italic> A betegek\n                    \u00e9letkora 8 \u00e9s 73 \u00e9v k\u00f6z\u00f6tt volt, \u00e1tlagosan 32 \u00e9v. N\u0151\/f\u00e9rfi ar\u00e1ny: 3,5:1. Az MG\n                    thymom\u00e1val t\u00e1rsult a betegek 12,7%-\u00e1ban. Tizenegy betegn\u00e9l rethymectomia,\n                    tov\u00e1bbi k\u00e9t betegn\u00e9l pedig sz\u00edvm\u0171t\u00e9t ut\u00e1n resternotomia t\u00f6rt\u00e9nt. Az els\u0151, 19\n                    \u00e9ves peri\u00f3dus el\u0151sz\u00f6r oper\u00e1lt, csak myastheni\u00e1s 525 beteg\u00e9b\u0151l 21,3%-ban\n                    k\u00f6vetkezett be l\u00e9gz\u00e9si el\u00e9gtelens\u00e9g a m\u0171t\u00e9t ut\u00e1n, s\u00fcrg\u0151s reintub\u00e1ci\u00f3 12,8%-ban,\n                    tracheostomia 11,2%-ban t\u00f6rt\u00e9nt. A m\u00e1sodik, 15 \u00e9ves peri\u00f3dus 338 beteg\u00e9n\u00e9l\n                    12,7%-ban volt posztoperat\u00edv l\u00e9gz\u00e9si el\u00e9gtelens\u00e9g, 7,1%-ban s\u00fcrg\u0151s\n                    reintub\u00e1ci\u00f3val, mind\u00f6ssze 1,2%\u2011ban l\u00e9gcs\u0151metsz\u00e9ssel kieg\u00e9sz\u00edtve. A 126 thymom\u00e1s\n                    betegn\u00e9l 19,1%-ban k\u00f6vetkezett be l\u00e9gz\u00e9si el\u00e9gtelens\u00e9g, 12,8%-os reintub\u00e1ci\u00f3val\n                    \u00e9s 20,6%-os tracheostomia ar\u00e1nnyal. A 13 reoper\u00e1lt betegn\u00e9l 46,1%-ban l\u00e9pett fel\n                    l\u00e9gz\u00e9si el\u00e9gtelens\u00e9g, 15,4%-os reintub\u00e1ci\u00f3val \u00e9s 46,1%-os tracheostomia\n                    ar\u00e1nnyal. S\u00falyos seb\u00e9szi sz\u00f6v\u0151dm\u00e9ny a teljes anyagban is kev\u00e9s volt: 2\n                    szegycsonti v\u00e9rz\u00e9s reoper\u00e1ci\u00f3t ig\u00e9nyelve, 1 tov\u00e1bbi reoper\u00e1ci\u00f3 dr\u00e9nbeszakad\u00e1s\n                    miatt, 4 mediastinitis az els\u0151 peri\u00f3dusban, k\u00e9t sz\u00edvs\u00e9r\u00fcl\u00e9s \u00e9s egy szegycsont\n                    sz\u00e9tv\u00e1l\u00e1s a m\u00e1sodik id\u0151szakban. A teljes m\u0171t\u00e9ti hal\u00e1loz\u00e1s 1,4% volt: els\u0151\n                    peri\u00f3dus (1,3%), m\u00e1sodik peri\u00f3dus (0,3%), thymom\u00e1s csoport (4%) \u00e9s a reoper\u00e1ci\u00f3k\n                    ut\u00e1n (7,7%). <jats:italic>K\u00f6vetkeztet\u00e9sek:<\/jats:italic> T\u00f6rt\u00e9neti \u00e1ttekint\u00e9sben\n                    jelent\u0151sen cs\u00f6kkent a transsternalis thymectomia s\u00falyos l\u00e9gz\u00e9si \u00e9s l\u00e9g\u00fati\n                    sz\u00f6v\u0151dm\u00e9nyeinek, valamint hal\u00e1loz\u00e1s\u00e1nak ar\u00e1nya, de a m\u0171t\u00e9tet k\u00f6vet\u0151 l\u00e9gz\u00e9si\n                    el\u00e9gtelens\u00e9g \u00e9s a szegycsont\u00e1tv\u00e1g\u00e1s seb\u00e9szi kock\u00e1zata tov\u00e1bbra is re\u00e1lis\n                    vesz\u00e9lynek tekinthet\u0151.<\/jats:p>","DOI":"10.1556\/1046.72.2019.3.1","type":"journal-article","created":{"date-parts":[[2019,9,22]],"date-time":"2019-09-22T09:29:50Z","timestamp":1569144590000},"page":"83-97","update-policy":"http:\/\/dx.doi.org\/10.1556\/policypage.crossmark.crossref.2","source":"Crossref","is-referenced-by-count":0,"title":["Myasthenia gravis: 1002 transsternalis thymectomia perioperat\u00edv sz\u00f6v\u0151dm\u00e9nyei \u2013 egy int\u00e9zm\u00e9ny 34 \u00e9ves gyakorlata t\u00f6rt\u00e9neti \u00e1ttekint\u00e9sben"],"prefix":"10.1556","volume":"72","author":[{"given":"J\u00f3zsef","family":"Kas","sequence":"first","affiliation":[{"name":"1 Mellkasseb\u00e9szet, Budai M\u00c1V K\u00f3rh\u00e1zBudapest"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00c1kos","family":"Kocsis","sequence":"additional","affiliation":[{"name":"1 Mellkasseb\u00e9szet, Budai M\u00c1V K\u00f3rh\u00e1zBudapest"},{"name":"5 Mellkasseb\u00e9szet, Orsz\u00e1gos Onkol\u00f3giai Int\u00e9zetBudapest (Jelenlegi munkahely\/Present working place)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dorottya","family":"Kiss","sequence":"additional","affiliation":[{"name":"2 AITO Budapest"},{"name":"6 AITK, Semmelweis EgyetemBudapest (Jelenlegi munkahely\/Present working place)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Veronika","family":"Simon","sequence":"additional","affiliation":[{"name":"2 AITO Budapest"},{"name":"7 AITO, Orsz\u00e1gos Onkol\u00f3giai Int\u00e9zetBudapest (Jelenlegi munkahely\/Present working place)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S\u00e1muel","family":"Komoly","sequence":"additional","affiliation":[{"name":"3 Neurol\u00f3giai Klinika, POTEP\u00e9cs"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Csilla","family":"R\u00f3zsa","sequence":"additional","affiliation":[{"name":"4 Neurol\u00f3gia, Jahn Ferenc D\u00e9l-pesti K\u00f3rh\u00e1z \u00e9s Rendel\u0151int\u00e9zetBudapest"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Egon","family":"Svastics","sequence":"additional","affiliation":[{"name":"1 Mellkasseb\u00e9szet, Budai M\u00c1V K\u00f3rh\u00e1zBudapest"},{"name":"8 \u00dajpesti Szakorvosi Rendel\u0151int\u00e9zet Budapest (Jelenlegi munkahely\/Present working place)"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","container-title":["Magyar Seb\u00e9szet (Hungarian Journal of Surgery)"],"original-title":[],"link":[{"URL":"https:\/\/akjournals.com\/view\/journals\/1046\/72\/3\/article-p83.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/akjournals.com\/downloadpdf\/journals\/1046\/72\/3\/article-p83.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/akjournals.com\/downloadpdf\/journals\/1046\/72\/3\/article-p83.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,3]],"date-time":"2024-01-03T15:56:05Z","timestamp":1704297365000},"score":1,"resource":{"primary":{"URL":"https:\/\/akjournals.com\/view\/journals\/1046\/72\/3\/article-p83.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9]]},"references-count":0,"journal-issue":{"issue":"3"},"URL":"https:\/\/doi.org\/10.1556\/1046.72.2019.3.1","relation":{},"ISSN":["0025-0295","1789-4301"],"issn-type":[{"value":"0025-0295","type":"print"},{"value":"1789-4301","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,9]]}}}