{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,3]],"date-time":"2022-04-03T18:42:48Z","timestamp":1649011368569},"reference-count":0,"publisher":"Akademiai Kiado Zrt.","issue":"4","content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":["MaSeb"],"published-print":{"date-parts":[[2020,12,12]]},"abstract":"\u00d6sszefoglal\u00f3.<\/jats:bold> A thoracoabdominalis aorta kirekeszt\u00e9se a gerincvel\u0151\n kering\u00e9s\u00e9nek cs\u00f6kken\u00e9s\u00e9t okozza. Az ischemia klinikailag paraparesis, paraplegia\n form\u00e1j\u00e1ban jelenik meg. Ez els\u0151sorban nyitott m\u0171t\u00e9tek sor\u00e1n jelent aligha\n kisz\u00e1m\u00edthat\u00f3 sz\u00f6v\u0151dm\u00e9nyt, de a modern endovascularis technik\u00e1k sem oldott\u00e1k meg\n teljes m\u00e9rt\u00e9kben ennek biztons\u00e1gos kiv\u00e9d\u00e9s\u00e9t \u2013 b\u00e1r ar\u00e1ny\u00e1t jelent\u0151sen\n m\u00e9rs\u00e9kelt\u00e9k. A javul\u00f3 eredm\u00e9nyek sz\u00e1mos t\u00e9nyez\u0151re vezethet\u0151k vissza, mint a\n kering\u00e9s kirekeszt\u00e9si idej\u00e9nek cs\u00f6kkent\u00e9se, a gerincvel\u0151-funkci\u00f3 \u00e9s metabolismus\n ellen\u0151rz\u00e9se. Mesters\u00e9ges kering\u00e9sjav\u00edt\u00f3 direkt \u00e9s indirekt elj\u00e1r\u00e1sok, liquor\n drainage, h\u0171t\u00e9s mellett a collateralis kering\u00e9s jav\u00edt\u00e1s\u00e1t szolg\u00e1l\u00f3\n prekondicion\u00e1l\u00f3 m\u00f3dszerek ker\u00fcltek bevezet\u00e9sre. K\u00eds\u00e9rletes munk\u00e1nkban 25\u201330 kg\n tests\u00faly\u00fa kuty\u00e1kon vizsg\u00e1ltuk \u2013 m\u00e1s param\u00e9terek mellett \u2013 a distalis perfusio\n n\u00f6vel\u00e9s\u00e9nek, a liquornyom\u00e1s cs\u00f6kkent\u00e9s\u00e9nek, illetve ezek kombin\u00e1ci\u00f3j\u00e1nak\n protekt\u00edv hat\u00e1s\u00e1t egy\u00f3r\u00e1s thoracoabdominalis aortakirekeszt\u00e9s sor\u00e1n.\n Dolgozatunkban a k\u00eds\u00e9rleti \u00e1llataink neurol\u00f3giai v\u00e9g\u00e1llapot\u00e1t a kering\u00e9si\n param\u00e9terek \u00e9s sz\u00f6veti perfusio \u00e9s a reperfusio v\u00e1ltoz\u00e1sainak \u00f6sszef\u00fcgg\u00e9sein\n kereszt\u00fcl t\u00e1rgyaljuk. Meg\u00e1llap\u00edtottuk, hogy distalis gerincvel\u0151 reperfusi\u00f3s\n hyperaemi\u00e1ja szorosan \u00f6sszef\u00fcgg a neurol\u00f3giai k\u00e1rosod\u00e1s m\u00e9rt\u00e9k\u00e9vel.<\/jats:p>\n Summary.<\/jats:bold> Clamping of the thoracoabdominal aorta reduces perfusion of\n the spinal cord significantly, which clinically may present as paraparesis or\n paraplegia \u2013 devastating and unpredictable complications of open\n thoracoabdominal aortic surgery. Introduction of monitoring of evoked potentials\n and\/or biochemical markers, methods increasing distal arterial pressure,\n indirect procedures enhancing residual flow (like liquor drainage), drugs, and\n use of hypothermia contributed to achieve better outcome. Preconditioning of\n spinal cord circulation is also a promising method. New endovascular techniques\n for thoracoabdominal aortic aneurysms and dissections reduced surgical trauma\n significantly. Despite all these progressions spinal cord ischemic damage is\n still a significant risk. To address this problem we carried out an experimental\n work using a canine model focusing on the protective effect of distal arterial\n perfusion, spinal fluid drainage, and their combination in a one hour setting of\n thoracoabdominal aortic clamping. In this paper we publish our data of\n circulatory and specific perfusion parameters of the spinal cord during and\n after declamping in correlation of final neurologic outcome.<\/jats:p>","DOI":"10.1556\/1046.73.2020.4.4","type":"journal-article","created":{"date-parts":[[2020,12,26]],"date-time":"2020-12-26T03:11:47Z","timestamp":1608952307000},"page":"153-159","update-policy":"http:\/\/dx.doi.org\/10.1556\/policypage.crossmark.crossref.1","source":"Crossref","is-referenced-by-count":0,"title":["A seb\u00e9szi gerincvel\u0151 ischemia \u00e9s reperfusio hat\u00e1sa a specifikus \u00e1t\u00e1raml\u00e1sra \u00e9s a neurol\u00f3giai k\u00f6vetkezm\u00e9nyekre"],"prefix":"10.1556","volume":"73","author":[{"given":"Csaba","family":"Dzsinich","sequence":"first","affiliation":[{"name":"1 MH Eg\u00e9szs\u00e9g\u00fcgyi K\u00f6zpont, Sz\u00edv-, \u00c9r- \u00e9s Mellkasseb\u00e9szet, Anaesthesiologia \u00e9s Intenz\u00edv Therapi\u00e1s Oszt\u00e1ly, 1134 Budapest, R\u00f3bert K. krt. 44."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P\u00e9ter","family":"Gloviczki","sequence":"additional","affiliation":[{"name":"2 Mayo Clinic, Gonda Vascular Center, Dept. Vascular Surgery, Rochester, Minnesota, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriella","family":"Nagy","sequence":"additional","affiliation":[{"name":"1 MH Eg\u00e9szs\u00e9g\u00fcgyi K\u00f6zpont, Sz\u00edv-, \u00c9r- \u00e9s Mellkasseb\u00e9szet, Anaesthesiologia \u00e9s Intenz\u00edv Therapi\u00e1s Oszt\u00e1ly, 1134 Budapest, R\u00f3bert K. krt. 44."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Klaudia Vivien","family":"Nagy","sequence":"additional","affiliation":[{"name":"3 SOTE V\u00e1rosmajori Sz\u00edv- \u00e9s \u00c9rgy\u00f3gy\u00e1szati Klinika, Budapest"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","container-title":["Magyar Seb\u00e9szet (Hungarian Journal of Surgery)"],"original-title":[],"link":[{"URL":"https:\/\/akjournals.com\/view\/journals\/1046\/73\/4\/article-p153.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/akjournals.com\/downloadpdf\/journals\/1046\/73\/4\/article-p153.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,7]],"date-time":"2021-08-07T05:03:57Z","timestamp":1628312637000},"score":1,"resource":{"primary":{"URL":"https:\/\/akjournals.com\/view\/journals\/1046\/73\/4\/article-p153.xml"}},"subtitle":["K\u00eds\u00e9rletes tanulm\u00e1ny"],"short-title":[],"issued":{"date-parts":[[2020,12,12]]},"references-count":0,"journal-issue":{"issue":"4"},"URL":"https:\/\/doi.org\/10.1556\/1046.73.2020.4.4","relation":{},"ISSN":["0025-0295","1789-4301"],"issn-type":[{"value":"0025-0295","type":"print"},{"value":"1789-4301","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,12,12]]}}}