{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,5]],"date-time":"2024-08-05T15:10:20Z","timestamp":1722870620775},"reference-count":9,"publisher":"Akademiai Kiado Zrt.","issue":"1","license":[{"start":{"date-parts":[[2021,3,16]],"date-time":"2021-03-16T00:00:00Z","timestamp":1615852800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":["MaSeb"],"published-print":{"date-parts":[[2021,3,16]]},"abstract":"<jats:p><jats:bold>\u00d6sszefoglal\u00f3.<\/jats:bold> A vena cava inferior leiomyosarcom\u00e1ja a vena tunica\n                    medi\u00e1j\u00e1b\u00f3l kiindul\u00f3 igen ritka rosszindulat\u00fa daganat. T\u00fcnetei \u00e9s\n                    radiomorfol\u00f3giai jelei nem mindig juttatnak pontos k\u00f3rism\u00e9hez, sz\u00f6vettani\n                    mintav\u00e9tele pedig elhelyezked\u00e9se miatt vesz\u00e9lyes lehet. Diagn\u00f3zisa ez\u00e9rt sokszor\n                    jelent kih\u00edv\u00e1st a klinikusok sz\u00e1m\u00e1ra. Kezel\u00e9se els\u0151sorban seb\u00e9szi, amelyet\n                    egy\u00fctt vagy monoter\u00e1pi\u00e1ban alkalmazott radioter\u00e1pia \u00e9s kemoter\u00e1pia eg\u00e9sz\u00edt\n                    ki.<\/jats:p>\n                <jats:p>Eset\u00fcnkben egy 74 \u00e9ves n\u0151beteg t\u00fcnetmentes, a v. cava inferior jobb v. renalis\n                    f\u00f6l\u00f6tti r\u00e9sz\u00e9nek jobb mell\u00e9kves\u00e9vel \u00f6sszef\u00fcgg\u0151 tumor\u00e1t tal\u00e1ltuk. Endokrinol\u00f3giai\n                    kivizsg\u00e1l\u00e1sa sor\u00e1n a sz\u00e9rum kortizol, adrenalin, noradrenalin, adenocorticotrop\n                    hormon (ACTH), teljes \u00e9s szabad tesztoszteron, dehidroepiandroszteron-szulf\u00e1t\n                    (DHEA-S), nemi hormon k\u00f6t\u0151feh\u00e9rje (sex hormone binding globulin, SHBG) norm\u00e1l\n                    tartom\u00e1nyban volt, a tumor hormonszekr\u00e9ci\u00f3t nem mutatott. A tumor seb\u00e9szi\n                    elt\u00e1vol\u00edt\u00e1sa mellett d\u00f6nt\u00f6tt\u00fcnk. Preoperat\u00edv biopszi\u00e1t annak kock\u00e1zatai miatt\n                    nem v\u00e9gezt\u00fcnk.<\/jats:p>\n                <jats:p>A m\u0171t\u00e9t sor\u00e1n a v. cava inferior daganat\u00e1t tal\u00e1ltuk, a tumor elt\u00e1vol\u00edt\u00e1s\u00e1t\n                    v\u00e9gezt\u00fck a vena fal\u00e1nak resecti\u00f3j\u00e1val, a jobb mell\u00e9kvese elt\u00e1vol\u00edt\u00e1s\u00e1val \u00e9s a\n                    jobb v. renalis neoimplantati\u00f3j\u00e1val. A jobb felt\u00e1r\u00e1s \u00e9rdek\u00e9ben a m\u0171t\u00e9t elej\u00e9n\n                    cholecystect\u00f3mi\u00e1t is v\u00e9gezt\u00fcnk. A m\u0171t\u00e9t ut\u00e1n sz\u00f6v\u0151dm\u00e9ny nem jelentkezett. A\n                    beteg adjuv\u00e1ns radioter\u00e1pi\u00e1ban r\u00e9szes\u00fclt.<\/jats:p>\n                <jats:p>A tumor korai diagn\u00f3zis\u00e1nak \u00e9s en bloc resecti\u00f3j\u00e1nak k\u00f6sz\u00f6nhet\u0151en jelent\u0151sen\n                    n\u00f6velt\u00fck a beteg gy\u00f3gyul\u00e1si es\u00e9lyeit, az elv\u00e9gzett radioter\u00e1pi\u00e1val pedig\n                    cs\u00f6kkentett\u00fck a recid\u00edva val\u00f3sz\u00edn\u0171s\u00e9g\u00e9t.<\/jats:p>\n                <jats:p><jats:bold>Summary.<\/jats:bold> Leiomyosacroma of the inferior vena cava is an extremely\n                    rare malignancy originating from the tunica media of the venous wall. Its\n                    symptoms and radiomorphological signs do not always lead to an accurate\n                    diagnosis. Histological sampling can be dangerous due to its location. Therefore\n                    the diagnosis is often a challenge for clinicians. Its treatment is primarily\n                    surgical, supplemented by radiotherapy and chemotherapy applied together or in\n                    monotherapy.<\/jats:p>\n                <jats:p>In our case, an asymptomatic 74-year-old female patient was diagnosed with a\n                    tumor of the inferior caval vein located just above the right renal vein and\n                    involving the right adrenal gland. As serum cortisol, epinephrine,\n                    norepinephrine, adrenocorticotropic hormone (ACTH), total and free testosterone,\n                    dehydroepiandrosterone sulfate (DHEA-S), sex hormone binding globulin (SHBG) was\n                    at normal level, the tumor showed no hormone secretion. Primary surgical\n                    resection was planned. Preoperative biopsy was not performed due to its high\n                    risk of complications.<\/jats:p>\n                <jats:p>During operation, tumor resection was performed by resection of the venous wall,\n                    removal of the right adrenal gland and neoimplantation of the right renal vein.\n                    For better exposure, cholecystectomy was also performed at the beginning of\n                    surgery. There were no postoperative complications. The patient received\n                    adjuvant radiation therapy.<\/jats:p>\n                <jats:p>Thanks to the early diagnosis of the tumor and the complete resection, we\n                    significantly increased the patient\u2019s chances of total recovery. With the\n                    radiotherapy performed, we reduced the likelihood of tumor recurrence.<\/jats:p>","DOI":"10.1556\/1046.74.2021.1.3","type":"journal-article","created":{"date-parts":[[2022,1,10]],"date-time":"2022-01-10T13:54:28Z","timestamp":1641822868000},"page":"22-26","update-policy":"http:\/\/dx.doi.org\/10.1556\/policypage.crossmark.crossref.1","source":"Crossref","is-referenced-by-count":0,"title":["Vena cava inferior leiomyosarcoma kezel\u00e9se cavotomi\u00e1val \u00e9s a jobb vena renalis neoimplantati\u00f3j\u00e1val"],"prefix":"10.1556","volume":"74","author":[{"given":"D\u00e1vid","family":"B\u00e1rdos","sequence":"first","affiliation":[{"name":"Semmelweis Egyetem, I. sz. Seb\u00e9szeti \u00e9s Intervenci\u00f3s Gasztroenterol\u00f3giai Klinika, 1085 Budapest, \u00dcll\u0151i \u00fat 78."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zolt\u00e1n","family":"Nagy","sequence":"additional","affiliation":[{"name":"Semmelweis Egyetem, I. sz. Seb\u00e9szeti \u00e9s Intervenci\u00f3s Gasztroenterol\u00f3giai Klinika, 1085 Budapest, \u00dcll\u0151i \u00fat 78."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Damj\u00e1n","family":"Pekli","sequence":"additional","affiliation":[{"name":"Semmelweis Egyetem, I. sz. Seb\u00e9szeti \u00e9s Intervenci\u00f3s Gasztroenterol\u00f3giai Klinika, 1085 Budapest, \u00dcll\u0151i \u00fat 78."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andr\u00e1s","family":"F\u00fcl\u00f6p","sequence":"additional","affiliation":[{"name":"Semmelweis Egyetem, I. sz. Seb\u00e9szeti \u00e9s Intervenci\u00f3s Gasztroenterol\u00f3giai Klinika, 1085 Budapest, \u00dcll\u0151i \u00fat 78."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Attila","family":"Szij\u00e1rt\u00f3","sequence":"additional","affiliation":[{"name":"Semmelweis Egyetem, I. sz. 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