{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T20:17:44Z","timestamp":1792095464681,"version":"4.4.0"},"reference-count":27,"publisher":"Akademiai Kiado Zrt.","issue":"4","license":[{"start":{"date-parts":[[2017,11,21]],"date-time":"2017-11-21T00:00:00Z","timestamp":1511222400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":["Interventional Medicine and Applied Science"],"published-print":{"date-parts":[[2017,11,21]]},"abstract":"<jats:sec sec-type=\"introduction\">\n          <jats:title>Introduction<\/jats:title>\n          <jats:p>Chronic periodontitis (CP) is an infectious disease resulting in inflammation of the supporting tissues of the teeth with progressive attachment loss and bone loss. This study aimed to evaluate the effect of 980-nm diode laser, as an adjunct to scaling and root planing (SRP) in the management of CP.<\/jats:p>\n        <\/jats:sec>\n        <jats:sec sec-type=\"methodology\">\n          <jats:title>Methodology<\/jats:title>\n          <jats:p>A total of 40 systemically healthy subjects diagnosed with CP were randomly assigned into two groups G1 (SRP and sham application of laser) and G2 (SRP and laser irradiation) with equal numbers in each. The levels of <jats:italic>Porphyromonas gingivalis<\/jats:italic> (<jats:italic>Pg<\/jats:italic>) were estimated from plaque samples using real-time polymerase chain reaction. Clinical and microbiological parameters were assessed at baseline, 4\u20136, and 12\u201314\u00a0weeks posttreatment in both groups.<\/jats:p>\n        <\/jats:sec>\n        <jats:sec sec-type=\"results\">\n          <jats:title>Results<\/jats:title>\n          <jats:p>A gradual reduction in the levels of <jats:italic>Pg<\/jats:italic> and improvement in clinical parameters were observed from baseline to 4\u20136 and 12\u201314\u00a0weeks in both groups. However, the comparison between groups, although clinically relevant, was not found to be statistically significant.<\/jats:p>\n        <\/jats:sec>\n        <jats:sec sec-type=\"conclusion\">\n          <jats:title>Conclusion<\/jats:title>\n          <jats:p>Although a 980-nm diode laser may not have any added benefit compared with SRP, it may emerge as an effective non-surgical treatment option in advanced periodontitis with complex inaccessible subgingival niches where comprehensive periodontal care may not be feasible.<\/jats:p>\n        <\/jats:sec>","DOI":"10.1556\/1646.9.2017.38","type":"journal-article","created":{"date-parts":[[2017,12,4]],"date-time":"2017-12-04T08:52:16Z","timestamp":1512377536000},"page":"191-198","update-policy":"https:\/\/doi.org\/10.1556\/policypage.crossmark.crossref.2","source":"Crossref","is-referenced-by-count":10,"title":["Diode laser therapy in the management of chronic periodontitis \u2013 A clinico-microbiological study"],"prefix":"10.1556","volume":"9","author":[{"given":"Kausar Jaha","family":"Yadwad","sequence":"first","affiliation":[{"name":"Department of Periodontology, KLE Society\u2019s Institute of Dental Sciences, Bangalore, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H. R.","family":"Veena","sequence":"additional","affiliation":[{"name":"Department of Periodontology, KLE Society\u2019s Institute of Dental Sciences, Bangalore, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sudhir R.","family":"Patil","sequence":"additional","affiliation":[{"name":"Department of Periodontology, KLE Society\u2019s Institute of Dental Sciences, Bangalore, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B. M.","family":"Shivaprasad","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Rajarajeshwari Dental College and Hospital, Bangalore, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"425","reference":[{"key":"B1","series-title":"Antimicrob Agents Chemother","first-page":"932","article-title":"In vivo killing of Porphyromonas gingivalis by toluidine blue-mediated photosensitization in an animal model.","volume":"47","author":"Komerik\n              N","year":"2003","unstructured":"Komerik\n              N\n            \n            , \n            \n              Nakanishi\n              H\n            \n            , \n            \n              MacRobert\n              AJ\n            \n            , \n            \n              Henderson\n              B\n            \n            , \n            \n              Speight\n              P\n            \n            , \n            \n              Wilson\n              M\n            \n          : In vivo killing of Porphyromonas gingivalis by toluidine blue-mediated photosensitization in an animal model.Antimicrob Agents Chemother47, 932\u2013940 (2003)"},{"key":"B2","series-title":"J Clin Microbiol","first-page":"4950","article-title":"Comparison of real-time PCR and culture for detection of Porphyromonas gingivalis in subgingival plaque samples","volume":"41","author":"Boutaga\n              K","year":"2003","unstructured":"Boutaga\n              K\n            \n            , \n            \n              Winkelhoff\n              AJ\n            \n            , \n            \n              Vandenbroucke-Grauls\n              CM\n            \n            , \n            \n              Savelkoul\n              PH\n            \n          : Comparison of real-time PCR and culture for detection of Porphyromonas gingivalis in subgingival plaque samples. J Clin Microbiol41, 4950\u20134954 (2003)"},{"key":"B3","series-title":"Periodontol 2000","first-page":"59","article-title":"Lasers in nonsurgical periodontal therapy","volume":"36","author":"Aoki\n              A","year":"2004","unstructured":"Aoki\n              A\n            \n            , \n            \n              Sasaki\n              MK\n            \n            , \n            \n              Watanabe\n              H\n            \n            , \n            \n              Ishikawa\n              I\n            \n          : Lasers in nonsurgical periodontal therapy. Periodontol 200036, 59\u201397 (2004)"},{"key":"B4","series-title":"New Microbiol","first-page":"513","article-title":"Use of diode laser 980 nm as adjunctive therapy in the treatment of chronic periodontitis. 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J Investig Clin Dent2, 38\u201342 (2011)"},{"key":"B10","series-title":"J Periodontol","first-page":"1018","article-title":"Effect of photodynamic therapy, diode laser, and deep scaling on cytokine and acute-phase protein levels in gingival crevicular fluid of residual periodontal pockets","volume":"83","author":"Giannopoulou\n              C","year":"2012","unstructured":"Giannopoulou\n              C\n            \n            , \n            \n              Cappuyns\n              I\n            \n            , \n            \n              Cancela\n              J\n            \n            , \n            \n              Cionca\n              N\n            \n            , \n            \n              Mombelli\n              A\n            \n          : Effect of photodynamic therapy, diode laser, and deep scaling on cytokine and acute-phase protein levels in gingival crevicular fluid of residual periodontal pockets. J Periodontol83, 1018\u20131027 (2012)"},{"key":"B11","series-title":"J Periodontol","first-page":"2021","article-title":"The effect of laser therapy as an adjunct to non-surgical periodontal treatment in subjects with chronic periodontitis: A systematic review.","volume":"79","author":"Karlsson\n              MR","year":"2008","unstructured":"Karlsson\n              MR\n            \n            , \n            \n              Lofgren\n              CD\n            \n            , \n            \n              Jansson\n              HM\n            \n          : The effect of laser therapy as an adjunct to non-surgical periodontal treatment in subjects with chronic periodontitis: A systematic review.J Periodontol79, 2021\u20132028 (2008)"},{"key":"B12","series-title":"J Periodontol","first-page":"798","article-title":"Detection of Tannerella forsythensis (Bacteroides forsythus) and Porphyromonas gingivalis by polymerase chain reaction in subjects with different periodontal status","volume":"74","author":"Klein\n              MI","year":"2003","unstructured":"Klein\n              MI\n            \n            , \n            \n              Gon\u00e7alves\n              RB\n            \n          : Detection of Tannerella forsythensis (Bacteroides forsythus) and Porphyromonas gingivalis by polymerase chain reaction in subjects with different periodontal status. 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Periodontol 20009, 150\u2013164 (1995)"},{"key":"B15","series-title":"J Periodontol","first-page":"1111","article-title":"Clinical effectiveness of diode laser therapy as an adjunct to non-surgical periodontal treatment: A randomized clinical study.","volume":"84","author":"Dukic\n              W","year":"2013","unstructured":"Dukic\n              W\n            \n            , \n            \n              Bago\n              I\n            \n            , \n            \n              Aurer\n              A\n            \n            , \n            \n              Roguljic\n              M\n            \n          : Clinical effectiveness of diode laser therapy as an adjunct to non-surgical periodontal treatment: A randomized clinical study.J Periodontol84, 1111\u20131117 (2013)"},{"key":"B16","series-title":"Compend Contin Educ Dent","first-page":"67","article-title":"Diode laser offers minimal benefit for periodontal therapy","volume":"33","author":"Cobb\n              CM","year":"2012","unstructured":"Cobb\n              CM\n            \n            , \n            \n              Blue\n              MS\n            \n            , \n            \n              Beaini\n              NE\n            \n            , \n            \n              Umaki\n              MR\n            \n            , \n            \n              Satheesh\n              KM\n            \n          : Diode laser offers minimal benefit for periodontal therapy. Compend Contin Educ Dent33, 67\u201373 (2012)"},{"key":"B17","series-title":"Clin Oral Investig","first-page":"87","article-title":"Clinical and microbiological evaluation of high intensity diode laser adjutant to non-surgical periodontal treatment: A 6-month clinical trial","volume":"17","author":"Euzebio Alves\n              VT","year":"2013","unstructured":"Euzebio Alves\n              VT\n            \n            , \n            \n              de Andrade\n              AK\n            \n            , \n            \n              Toaliar\n              JM\n            \n            , \n            \n              Conde\n              MC\n            \n            , \n            \n              Zezell\n              DM\n            \n            , \n            \n              Cai\n              S\n            \n            , \n            \n              Pannuti\n              CM\n            \n            , \n            \n              De Micheli\n              G\n            \n          : Clinical and microbiological evaluation of high intensity diode laser adjutant to non-surgical periodontal treatment: A 6-month clinical trial. 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J Clin Periodontol27, 30\u201336 (2000)"},{"key":"B23","series-title":"J Clin Periodontol","first-page":"437","article-title":"Effect of non-surgical periodontal treatment on clinical parameters and the numbers of Porphyromonas gingivalis, Prevotella intermedia and Actinobacillus actinomycetemcomitans at adult periodontitis sites.","volume":"28","author":"Doungudomdacha\n              S","year":"2001","unstructured":"Doungudomdacha\n              S\n            \n            , \n            \n              Rawlinson\n              A\n            \n            , \n            \n              Walsch\n              TF\n            \n            , \n            \n              Douglas\n              CW\n            \n          : Effect of non-surgical periodontal treatment on clinical parameters and the numbers of Porphyromonas gingivalis, Prevotella intermedia and Actinobacillus actinomycetemcomitans at adult periodontitis sites.J Clin Periodontol28, 437\u2013445 (2001)"},{"key":"B24","series-title":"J Zhejiang Univ Sci B","first-page":"121","article-title":"Association between infection of different strains of Porphyromonas gingivalis and Actinobacillus actinomycetemcomitans in subgingival plaque and clinical parameters in chronic periodontitis","volume":"8","author":"Wu\n              YM","year":"2007","unstructured":"Wu\n              YM\n            \n            , \n            \n              Yan\n              J\n            \n            , \n            \n              Chen\n              L\n            \n            , \n            \n              Zhi\n              GY\n            \n          : Association between infection of different strains of Porphyromonas gingivalis and Actinobacillus actinomycetemcomitans in subgingival plaque and clinical parameters in chronic periodontitis. 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J Clin Microbiol36, 3239\u20133242 (1998)"},{"key":"B27","series-title":"J Periodontol","first-page":"1077","article-title":"Occurrence of Porphyromonas gingivalis and Tannerella forsythensis in periodontally diseased and healthy subjects.","volume":"75","author":"Yang\n              HW","year":"2004","unstructured":"Yang\n              HW\n            \n            , \n            \n              Huang\n              YF\n            \n            , \n            \n              Chou\n              MY\n            \n          : Occurrence of Porphyromonas gingivalis and Tannerella forsythensis in periodontally diseased and healthy subjects.J Periodontol75, 1077\u20131083 (2004)"}],"container-title":["Interventional Medicine and Applied Science"],"original-title":[],"link":[{"URL":"http:\/\/www.akademiai.com\/doi\/full-xml\/10.1556\/1646.9.2017.38","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/akjournals.com\/view\/journals\/1646\/9\/4\/article-p191.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/akjournals.com\/downloadpdf\/journals\/1646\/9\/4\/article-p191.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/akjournals.com\/downloadpdf\/journals\/1646\/9\/4\/article-p191.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,3]],"date-time":"2024-01-03T16:25:01Z","timestamp":1704299101000},"score":1,"resource":{"primary":{"URL":"https:\/\/akjournals.com\/view\/journals\/1646\/9\/4\/article-p191.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11,21]]},"references-count":27,"journal-issue":{"issue":"4"},"URL":"https:\/\/doi.org\/10.1556\/1646.9.2017.38","relation":{},"ISSN":["2061-1617","2061-5094"],"issn-type":[{"value":"2061-1617","type":"print"},{"value":"2061-5094","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,11,21]]}}}