{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T12:59:24Z","timestamp":1793105964307,"version":"4.5.0"},"reference-count":62,"publisher":"Akademiai Kiado Zrt.","issue":"2","license":[{"start":{"date-parts":[[2024,5,14]],"date-time":"2024-05-14T00:00:00Z","timestamp":1715644800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100012550","name":"National Research Development and Innovation Fund","doi-asserted-by":"crossref","award":["\u00daNKP-23-1-SZTE-146"],"award-info":[{"award-number":["\u00daNKP-23-1-SZTE-146"]}],"id":[{"id":"10.13039\/501100012550","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":["EuJMI"],"published-print":{"date-parts":[[2024,5,14]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The clinical role of <jats:italic>Acinetobacter baumannii<\/jats:italic> has been highlighted in numerous infectious syndromes with a high mortality rate, due to the high prevalence of multidrug-resistant (MDR) isolates. The treatment and eradication of this pathogen is hindered by biofilm-formation, providing protection from noxious environmental factors and antimicrobials. The aim of this study was to assess the antibiotic susceptibility, antiseptic susceptibility and biofilm-forming capacity using phenotypic methods in environmental <jats:italic>A.\u00a0baumannii<\/jats:italic> isolates. One hundred and fourteen (<jats:italic>n<\/jats:italic> = 114) isolates were collected, originating from various environmental sources and geographical regions. Antimicrobial susceptibility testing was carried out using the disk diffusion method, while antiseptic susceptibility was performed using the agar dilution method. Determination of biofilm-forming capacity was carried out using a microtiter-plate based method. Resistance in environmental <jats:italic>A. baumannii<\/jats:italic> isolates were highest for ciprofloxacin (64.03%, <jats:italic>n<\/jats:italic> = 73), levofloxacin (62.18%, <jats:italic>n<\/jats:italic> = 71) and trimethoprim-sulfamethoxazole (61.40%, <jats:italic>n<\/jats:italic> = 70), while lowest for colistin (1.75%, <jats:italic>n<\/jats:italic>\u00a0= 2). Efflux pump overexpression was seen in 48.25% of isolates (<jats:italic>n<\/jats:italic> = 55), 49.12% (<jats:italic>n<\/jats:italic> = 56) were classified as MDR. 6.14% (<jats:italic>n<\/jats:italic> = 7), 9.65% (<jats:italic>n<\/jats:italic> = 11), 24.65% (<jats:italic>n<\/jats:italic> = 28) and 59.65% (<jats:italic>n<\/jats:italic> = 68) of isolates were non-biofilm producers, weak, medium, and strong biofilm producers, respectively. No significant differences were observed between non-MDR vs. MDR isolates regarding their distribution of biofilm-producers (<jats:italic>P<\/jats:italic> = 0.655). The MIC ranges for the tested antiseptics were as follows: benzalkonium chloride 16\u2013128\u2009\u03bcg mL<jats:sup>\u22121<\/jats:sup>, chlorhexidine digluconate 4\u2013128\u2009\u03bcg mL<jats:sup>\u22121<\/jats:sup>, formaldehyde 64\u2013256\u2009\u03bcg mL<jats:sup>\u22121<\/jats:sup> and triclosan 2\u201316\u2009\u03bcg mL<jats:sup>\u22121<\/jats:sup>, respectively. The conscientious use of antiseptics, together with periodic surveillance, is essential to curb the spread of these bacteria, and to maintain current infection prevention capabilities.<\/jats:p>","DOI":"10.1556\/1886.2024.00014","type":"journal-article","created":{"date-parts":[[2024,3,5]],"date-time":"2024-03-05T12:31:59Z","timestamp":1709641919000},"page":"126-133","update-policy":"https:\/\/doi.org\/10.1556\/policypage.crossmark.crossref.2","source":"Crossref","is-referenced-by-count":15,"title":["Characterization of antibiotic and disinfectant susceptibility in biofilm-forming Acinetobacter baumannii: A focus on environmental isolates"],"prefix":"10.1556","volume":"14","author":[{"given":"P\u00e9ter","family":"Pall\u00f3s","sequence":"first","affiliation":[{"name":"Department of Oral Biology and Experimental Dental Research, Faculty of Dentistry, University of Szeged, Tisza Lajos krt. 64-66., 6720 Szeged, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1270-0365","authenticated-orcid":true,"given":"M\u00e1ri\u00f3","family":"Gajd\u00e1cs","sequence":"additional","affiliation":[{"name":"Department of Oral Biology and Experimental Dental Research, Faculty of Dentistry, University of Szeged, Tisza Lajos krt. 64-66., 6720 Szeged, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edit","family":"Urb\u00e1n","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology and Immunology, University of P\u00e9cs Medical School, Szigeti \u00fat 12, 7624 P\u00e9cs, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yvett","family":"Szabados","sequence":"additional","affiliation":[{"name":"Department of Oral Biology and Experimental Dental Research, Faculty of Dentistry, University of Szeged, Tisza Lajos krt. 64-66., 6720 Szeged, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Klaudia","family":"Szalai","sequence":"additional","affiliation":[{"name":"Department of Oral Biology and Experimental Dental Research, Faculty of Dentistry, University of Szeged, Tisza Lajos krt. 64-66., 6720 Szeged, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L\u00edvia","family":"Hevesi","sequence":"additional","affiliation":[{"name":"Department of Oral Biology and Experimental Dental Research, Faculty of Dentistry, University of Szeged, Tisza Lajos krt. 64-66., 6720 Szeged, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Horv\u00e1th","sequence":"additional","affiliation":[{"name":"Department of Oral Biology and Experimental Dental Research, Faculty of Dentistry, University of Szeged, Tisza Lajos krt. 64-66., 6720 Szeged, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Kuklis","sequence":"additional","affiliation":[{"name":"Department of Oral Biology and Experimental Dental Research, Faculty of Dentistry, University of Szeged, Tisza Lajos krt. 64-66., 6720 Szeged, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Devina","family":"Morjaria","sequence":"additional","affiliation":[{"name":"Department of Oral Biology and Experimental Dental Research, Faculty of Dentistry, University of Szeged, Tisza Lajos krt. 64-66., 6720 Szeged, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wajiha","family":"Iffat","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutics, Dow College of Pharmacy, Faculty of Pharmacy and Pharmaceutical Sciences, Dow University of Health Sciences, OJHA Campus, Karachi, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helal F.","family":"Hetta","sequence":"additional","affiliation":[{"name":"Department of Natural Products and Alternative Medicine, Division of Microbiology and Immunology, Faculty of Pharmacy, University of Tabuk, Tabuk 71491, Saudi Arabia"},{"name":"Department of Medical Microbiology and Immunology, Faculty of Medicine, Assiut University, Assiut, 71515, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicola","family":"Piredda","sequence":"additional","affiliation":[{"name":"Radiology Unit, Giovanni Paolo II Hospital, ASL Gallura, 07026 Olbia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew Gavino","family":"Donadu","sequence":"additional","affiliation":[{"name":"Hospital Pharmacy, Giovanni Paolo II Hospital, ASL Gallura, 07026 Olbia, Italy"},{"name":"Department of Medicine, Surgery and Pharmacy, Scuola di Specializzazione in Farmacia Ospedaliera, University of Sassari, 07100 Sassari, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"425","reference":[{"key":"B1","series-title":"World J Emerg Med","first-page":"169","article-title":"The Acinetobacter baumannii group: a systemic review","volume":"4","author":"Zhang HZ","year":"2013","unstructured":"Zhang HZ, Zhanh JS, Qiao L. 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