{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T23:13:52Z","timestamp":1790810032787,"version":"4.1.0"},"reference-count":27,"publisher":"Akademiai Kiado Zrt.","issue":"2","license":[{"start":{"date-parts":[[2024,5,14]],"date-time":"2024-05-14T00:00:00Z","timestamp":1715644800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"The Secretary of Public Education, Mexico","award":["DSA\/103.5\/14\/11311"],"award-info":[{"award-number":["DSA\/103.5\/14\/11311"]}]}],"content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":["EuJMI"],"published-print":{"date-parts":[[2024,5,14]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Abdominal pain has been rarely reported in individuals infected with <jats:italic>Toxoplasma gondii<\/jats:italic> (<jats:italic>T. gondii<\/jats:italic>). The aim of this study was to determine the association between <jats:italic>T. gondii<\/jats:italic> infection and abdominal pain. Two hundred and ninety-nine patients with abdominal pain (cases) and 299 age- and gender-matched people without abdominal pain (controls) were tested for anti-<jats:italic>T. gondii<\/jats:italic> IgG and IgM antibodies. Twenty-four (8.0%) of the 299 cases and 12 (4.0%) of the 299 controls were positive for anti-<jats:italic>T. gondii<\/jats:italic> IgG antibodies (OR: 2.08; 95% CI: 1.02\u20134.25; <jats:italic>P<\/jats:italic> = 0.03). The seroprevalence of <jats:italic>T. gondii<\/jats:italic> infection was significantly higher in women with frequent abdominal pain than in women without this clinical feature (OR: 2.30; 95% CI: 1.06\u20134.96; <jats:italic>P<\/jats:italic> = 0.02). Twelve (4.0%) of the 299 cases and 7 (2.3%) of the 299 controls had high (&gt;150 IU mL<jats:sup>\u22121<\/jats:sup>) anti-<jats:italic>T. gondii<\/jats:italic> IgG antibody levels (OR: 1.74; 95% CI: 0.67\u20134.49; <jats:italic>P<\/jats:italic> = 0.24). Seven (29.2%) of the 24 cases with anti-<jats:italic>T. gondii<\/jats:italic> IgG antibodies and 3 (25.0%) of the 12 controls with\u00a0anti-<jats:italic>T. gondii<\/jats:italic> IgG antibodies were positive to anti-<jats:italic>T. gondii<\/jats:italic> IgM antibodies (OR: 1.23; 95% CI:\u00a00.25\u20135.97; <jats:italic>P<\/jats:italic> = 1.00). Results suggest an association between <jats:italic>T. gondii<\/jats:italic> infection and frequent abdominal pain. Further research to confirm this association should be conducted.<\/jats:p>","DOI":"10.1556\/1886.2024.00025","type":"journal-article","created":{"date-parts":[[2024,4,2]],"date-time":"2024-04-02T07:46:20Z","timestamp":1712043980000},"page":"180-184","update-policy":"https:\/\/doi.org\/10.1556\/policypage.crossmark.crossref.2","source":"Crossref","is-referenced-by-count":3,"title":["Association between Toxoplasma gondii exposure and abdominal pain: An age- and gender-matched case-control seroprevalence study"],"prefix":"10.1556","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0367-6052","authenticated-orcid":true,"given":"Cosme","family":"Alvarado-Esquivel","sequence":"first","affiliation":[{"name":"Biomedical Research Laboratory, Faculty of Medicine and Nutrition, Ju\u00e1rez University of Durango State, Avenida Universidad S\/N, 34000 Durango, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergio","family":"Estrada-Mart\u00ednez","sequence":"additional","affiliation":[{"name":"Institute for Scientific Research \u201cDr. Roberto Rivera-Damm\u201d, Ju\u00e1rez University of Durango State, Avenida Universidad S\/N, 34000 Durango, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agar","family":"Ramos-Nevarez","sequence":"additional","affiliation":[{"name":"Cl\u00ednica de Medicina Familiar, Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado, Predio Canoas S\/N, 34079 Durango, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c1ngel Osvaldo","family":"Alvarado-F\u00e9lix","sequence":"additional","affiliation":[{"name":"Biomedical Research Laboratory, Faculty of Medicine and Nutrition, Ju\u00e1rez University of Durango State, Avenida Universidad S\/N, 34000 Durango, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra Margarita","family":"Cerrillo-Soto","sequence":"additional","affiliation":[{"name":"Cl\u00ednica de Medicina Familiar, Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado, Predio Canoas S\/N, 34079 Durango, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gustavo Alexis","family":"Alvarado-F\u00e9lix","sequence":"additional","affiliation":[{"name":"Biomedical Research Laboratory, Faculty of Medicine and Nutrition, Ju\u00e1rez University of Durango State, Avenida Universidad S\/N, 34000 Durango, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos Alberto","family":"Guido-Arreola","sequence":"additional","affiliation":[{"name":"Cl\u00ednica de Medicina Familiar, Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado, Predio Canoas S\/N, 34079 Durango, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leandro","family":"Saenz-Soto","sequence":"additional","affiliation":[{"name":"Cl\u00ednica de Medicina Familiar, Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado, Predio Canoas S\/N, 34079 Durango, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"425","reference":[{"key":"B1","series-title":"Epidemiol Infect","first-page":"1","article-title":"Human toxoplasmosis: a systematic review for genetic diversity of Toxoplasma gondii in clinical samples","volume":"147","author":"Hosseini SA","year":"2018 Nov 5","unstructured":"Hosseini SA, Amouei A, Sharif M, Sarvi S, Galal L, Javidnia J, et\u00a0al. 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