{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T15:13:06Z","timestamp":1789053186884,"version":"build-2803163510"},"reference-count":25,"publisher":"Akademiai Kiado Zrt.","issue":"1","license":[{"start":{"date-parts":[[2025,3,19]],"date-time":"2025-03-19T00:00:00Z","timestamp":1742342400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":["EuJMI"],"published-print":{"date-parts":[[2025,3,19]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Aronia melanocarpa<\/jats:italic>, a main constituent of black chokeberry, provides a rich source of bioactive molecules including polyphenols, flavonoids, and anthocyanins and has been used for long in traditional medicine due to its various health-promoting and disease-alleviating properties. The aim of our literature survey was to provide an actual update of evidence regarding the antibacterial activities exerted by <jats:italic>Aronia melanocarpa<\/jats:italic> and its potential application for the treatment of human bacterial pathogenic including food-borne infections. Our survey revealed that distinct ingredients in <jats:italic>Aronia melanocarpa<\/jats:italic> do not only inhibit growth of Gram-positive and to a lesser extent of Gram-negative bacteria, but also biofilm formation that is even more pronounced upon combined application. Furthermore, the anti-microbial effects against food-spoiling bacteria underscores the application of defined Aronia-derived molecules in food preservation decreasing the risk for transmission of food-borne pathogens and thereby, improving food safety. Notably, <jats:italic>in vivo<\/jats:italic> studies revealed that prophylactic Aronia juice application alleviated murine <jats:italic>Listeria monocytogenes<\/jats:italic>-induced enteritis, dampened growth of streptococci involved in dental caries development, and decreased the incidence of urinary tract infections in nursing home residents. In conclusion, Aronia-derived bioactive molecules exhibit promising anti-bacterial and disease-alleviating effects that should be further elucidated in clinical studies.<\/jats:p>","DOI":"10.1556\/1886.2024.00139","type":"journal-article","created":{"date-parts":[[2025,2,12]],"date-time":"2025-02-12T10:48:06Z","timestamp":1739357286000},"page":"13-20","update-policy":"https:\/\/doi.org\/10.1556\/policypage.crossmark.crossref.2","source":"Crossref","is-referenced-by-count":7,"title":["A review of the anti-bacterial effects exerted by Aronia melanocarpa"],"prefix":"10.1556","volume":"15","author":[{"given":"Shirin Azizi","family":"Ghanbari","sequence":"first","affiliation":[{"name":"Institute of Microbiology, Infectious Diseases, and Immunology, Gastrointestinal Microbiology Research Group, Charit\u00e9 \u2013 University Medicine Berlin, Corporate Member of Freie Universit\u00e4t Berlin, Humboldt-Universit\u00e4t zu Berlin, and Berlin Institute of Health, Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soraya","family":"Mousavi","sequence":"additional","affiliation":[{"name":"Institute of Microbiology, Infectious Diseases, and Immunology, Gastrointestinal Microbiology Research Group, Charit\u00e9 \u2013 University Medicine Berlin, Corporate Member of Freie Universit\u00e4t Berlin, Humboldt-Universit\u00e4t zu Berlin, and Berlin Institute of Health, Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Bereswill","sequence":"additional","affiliation":[{"name":"Institute of Microbiology, Infectious Diseases, and Immunology, Gastrointestinal Microbiology Research Group, Charit\u00e9 \u2013 University Medicine Berlin, Corporate Member of Freie Universit\u00e4t Berlin, Humboldt-Universit\u00e4t zu Berlin, and Berlin Institute of Health, Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6399-651X","authenticated-orcid":true,"given":"Markus M.","family":"Heimesaat","sequence":"additional","affiliation":[{"name":"Institute of Microbiology, Infectious Diseases, and Immunology, Gastrointestinal Microbiology Research Group, Charit\u00e9 \u2013 University Medicine Berlin, Corporate Member of Freie Universit\u00e4t Berlin, Humboldt-Universit\u00e4t zu Berlin, and Berlin Institute of Health, Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"425","reference":[{"issue":"3","key":"B1","series-title":"Microbiol Mol Biol Rev","first-page":"417","article-title":"Origins and evolution of antibiotic resistance","volume":"74","author":"Davies J","year":"2010","unstructured":"Davies J, Davies D. Origins and evolution of antibiotic resistance. Microbiol Mol Biol Rev. 2010;74(3):417\u201333."},{"issue":"8","key":"B2","series-title":"Lancet Infect Dis","first-page":"742","article-title":"Global antibiotic consumption 2000 to 2010: an analysis of national pharmaceutical sales data","volume":"14","author":"Van Boeckel TP","year":"2014","unstructured":"Van Boeckel TP, Gandra S, Ashok A, Caudron Q, Grenfell BT, Levin SA, et\u00a0al. Global antibiotic consumption 2000 to 2010: an analysis of national pharmaceutical sales data. Lancet Infect Dis. 2014;14(8):742\u201350."},{"issue":"18","key":"B3","series-title":"Proc Natl Acad Sci U S A","first-page":"5649","article-title":"Global trends in antimicrobial use in food animals","volume":"112","author":"Van Boeckel TP","year":"2015","unstructured":"Van Boeckel TP, Brower C, Gilbert M, Grenfell BT, Levin SA, Robinson TP, et\u00a0al. Global trends in antimicrobial use in food animals. 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J Med Food. 2010;13(2):255\u201369."},{"key":"B8","series-title":"Trends Food Sci & Technology","first-page":"45","article-title":"Black chokeberry (Aronia melanocarpa) and its products as potential health-promoting factors-An overview","volume":"89","author":"Sidor A","year":"2019","unstructured":"Sidor A, Dro\u017cd\u017cy\u0144ska A, Gramza-Micha\u0142owska A. Black chokeberry (Aronia melanocarpa) and its products as potential health-promoting factors-An overview. Trends Food Sci & Technology. 2019;89:45\u201360."},{"key":"B9","series-title":"Food Res Dev","first-page":"206","article-title":"Advances in studies on the function and application of Aronia melanocarpa","volume":"42","author":"Yang S","year":"2021","unstructured":"Yang S, Wang D, Gao Y. Advances in studies on the function and application of Aronia melanocarpa. Food Res Dev. 2021;42:206\u201313."},{"issue":"7","key":"B10","series-title":"Antioxidants (Basel, Switzerland)","article-title":"Aronia melanocarpa products and by-products for health and nutrition: a review","volume":"10","author":"Jurendi\u0107 T","year":"2021","unstructured":"Jurendi\u0107 T, \u0160\u010detar M. Aronia melanocarpa products and by-products for health and nutrition: a review. Antioxidants (Basel, Switzerland). 2021;10(7)."},{"issue":"22","key":"B11","series-title":"Molecules","article-title":"Potential benefits of black chokeberry (Aronia melanocarpa) fruits and their constituents in improving human health","volume":"27","author":"Ren Y","year":"2022","unstructured":"Ren Y, Frank T, Meyer G, Lei J, Grebenc JR, Slaughter R, et\u00a0al. Potential benefits of black chokeberry (Aronia melanocarpa) fruits and their constituents in improving human health. Molecules. 2022;27(22)."},{"issue":"3","key":"B12","series-title":"Plant Foods Hum Nutr.","first-page":"427","article-title":"Antioxidant and antimicrobial properties of selected fruit juices","volume":"77","author":"Nowak D","year":"2022","unstructured":"Nowak D, Go\u015bli\u0144ski M, K\u0142\u0119bukowska L. Antioxidant and antimicrobial properties of selected fruit juices. Plant Foods Hum Nutr. 2022;77(3):427\u201335."},{"issue":"5","key":"B13","series-title":"J\u00a0Sci Food Agric","first-page":"2311","article-title":"Antibacterial and antioxidative properties of different parts of garden rhubarb, blackcurrant, chokeberry and blue honeysuckle","volume":"99","author":"Raudsepp P","year":"2019","unstructured":"Raudsepp P, Koskar J, Anton D, Merem\u00e4e K, Kapp K, Laurson P, et\u00a0al. Antibacterial and antioxidative properties of different parts of garden rhubarb, blackcurrant, chokeberry and blue honeysuckle. J\u00a0Sci Food Agric. 2019;99(5):2311\u201320."},{"issue":"26","key":"B14","series-title":"J Agric Food Chem.","first-page":"8032","article-title":"TMT-based quantitative proteomics analyses reveal the antibacterial mechanisms of anthocyanins from aronia melanocarpa against Escherichia coli O157:H7","volume":"70","author":"Deng H","year":"2022","unstructured":"Deng H, Xue B, Wang M, Tong Y, Tan C, Wan M, et\u00a0al. TMT-based quantitative proteomics analyses reveal the antibacterial mechanisms of anthocyanins from aronia melanocarpa against Escherichia coli O157:H7. J Agric Food Chem. 2022;70(26):8032\u201342."},{"key":"B15","series-title":"Curr Res Food Sci","first-page":"1559","article-title":"Proteomic analyses revealed the antibacterial mechanism of Aronia melanocarpa isolated anthocyanins against Escherichia coli O157: H7","volume":"5","author":"Deng H","year":"2022","unstructured":"Deng H, Kong Y, Zhu J, Jiao X, Tong Y, Wan M, et\u00a0al. Proteomic analyses revealed the antibacterial mechanism of Aronia melanocarpa isolated anthocyanins against Escherichia coli O157: H7. Curr Res Food Sci. 2022;5:1559\u201369."},{"issue":"12","key":"B16","series-title":"Molecules","first-page":"14989","article-title":"Effects of Aronia melanocarpa constituents on biofilm formation of Escherichia coli and Bacillus cereus","volume":"18","author":"Br\u00e4unlich M","year":"2013","unstructured":"Br\u00e4unlich M, \u00d8kstad OA, Slimestad R, Wangensteen H, Malterud KE, Barsett H. Effects of Aronia melanocarpa constituents on biofilm formation of Escherichia coli and Bacillus cereus. Molecules. 2013;18(12):14989\u201399."},{"issue":"9","key":"B17","series-title":"Food Sci Biotechnol","first-page":"1295","article-title":"Antibacterial and in vitro antidementia effects of aronia (Aronia melanocarpa) leaf extracts","volume":"29","author":"Kim SS","year":"2020","unstructured":"Kim SS, Shin Y. Antibacterial and in vitro antidementia effects of aronia (Aronia melanocarpa) leaf extracts. Food Sci Biotechnol. 2020;29(9):1295\u2013300."},{"issue":"9","key":"B18","series-title":"Molecules","article-title":"Composition and antibacterial activity of Aronia melanocarpa (Michx.) Elliot, Cornus mas L. and Chaenomeles superba Lindl. Leaf extracts","volume":"25","author":"Efenberger-Szmechtyk M","year":"2020","unstructured":"Efenberger-Szmechtyk M, Nowak A, Czy\u017cowska A, Kucharska AZ, Fecka I. Composition and antibacterial activity of Aronia melanocarpa (Michx.) Elliot, Cornus mas L. and Chaenomeles superba Lindl. Leaf extracts. Molecules. 2020;25(9)."},{"key":"B19","series-title":"Food Chem.","article-title":"Antibacterial mechanisms of Aronia melanocarpa (Michx.), Chaenomeles superba Lindl. and Cornus mas L. leaf extracts","volume":"350","author":"Efenberger-Szmechtyk M","year":"2021","unstructured":"Efenberger-Szmechtyk M, Nowak A, Czy\u017cowska A, \u015aniadowska M, Otlewska A, \u017by\u017celewicz D. Antibacterial mechanisms of Aronia melanocarpa (Michx.), Chaenomeles superba Lindl. and Cornus mas L. leaf extracts. Food Chem. 2021;350:129218."},{"issue":"9","key":"B20","series-title":"Pharmaceutics","article-title":"Biological evaluation of black chokeberry extract free and embedded in two mesoporous silica-type matrices","volume":"12","author":"Buda V","year":"2020","unstructured":"Buda V, Brezoiu AM, Berger D, Pavel IZ, Muntean D, Minda D, et\u00a0al. Biological evaluation of black chokeberry extract free and embedded in two mesoporous silica-type matrices. Pharmaceutics. 2020;12(9)."},{"key":"B21","series-title":"Int J Biol Macromol","first-page":"381","article-title":"Antimicrobial, antioxidant, and pH-sensitive polyvinyl alcohol\/chitosan-based composite films with aronia extract, cellulose nanocrystals, and grapefruit seed extract","volume":"213","author":"Oun AA","year":"2022","unstructured":"Oun AA, Shin GH, Kim JT. Antimicrobial, antioxidant, and pH-sensitive polyvinyl alcohol\/chitosan-based composite films with aronia extract, cellulose nanocrystals, and grapefruit seed extract. Int J Biol Macromol. 2022;213:381\u201393."},{"issue":"11","key":"B22","series-title":"Foods","article-title":"Fabrication of functional bioelastomer for food packaging from aronia (Aronia melanocarpa) juice processing by-products","volume":"9","author":"Lee KH","year":"2020","unstructured":"Lee KH, Chun Y, Jang YW, Lee SK, Kim HR, Lee JH, et\u00a0al. Fabrication of functional bioelastomer for food packaging from aronia (Aronia melanocarpa) juice processing by-products. Foods. 2020;9(11)."},{"issue":"9","key":"B23","series-title":"Food Funct","first-page":"7793","article-title":"Immunomodulatory activity and protective effects of chokeberry fruit extract on Listeria monocytogenes infection in mice","volume":"11","author":"Gaji\u0107 D","year":"2020","unstructured":"Gaji\u0107 D, Saksida T, Koprivica I, \u0160enerovi\u0107 L, Mori\u0107 I, \u0160avikin K, et\u00a0al. Immunomodulatory activity and protective effects of chokeberry fruit extract on Listeria monocytogenes infection in mice. Food Funct. 2020;11(9):7793\u2013803."},{"issue":"4","key":"B24","series-title":"J Sci Food Agric","first-page":"1806","article-title":"Inhibition of streptococcal biofilm formation by Aronia by extracellular RNA degradation","volume":"100","author":"Lee HJ","year":"2020","unstructured":"Lee HJ, Oh SY, Hong SH. Inhibition of streptococcal biofilm formation by Aronia by extracellular RNA degradation. J Sci Food Agric. 2020;100(4):1806\u201311."},{"issue":"6","key":"B25","series-title":"Nutr Res","first-page":"518","article-title":"Black chokeberry juice (Aronia melanocarpa) reduces incidences of urinary tract infection among nursing home residents in the long term--a pilot study","volume":"34","author":"Handeland M","year":"2014","unstructured":"Handeland M, Grude N, Torp T, Slimestad R. Black chokeberry juice (Aronia melanocarpa) reduces incidences of urinary tract infection among nursing home residents in the long term--a pilot study. Nutr Res. 2014;34(6):518\u201325."}],"container-title":["European Journal of Microbiology and Immunology"],"original-title":[],"link":[{"URL":"https:\/\/akjournals.com\/view\/journals\/1886\/15\/1\/article-p13.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/akjournals.com\/downloadpdf\/journals\/1886\/15\/1\/article-p13.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/akjournals.com\/downloadpdf\/journals\/1886\/15\/1\/article-p13.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,19]],"date-time":"2025-03-19T12:16:29Z","timestamp":1742386589000},"score":1,"resource":{"primary":{"URL":"https:\/\/akjournals.com\/view\/journals\/1886\/15\/1\/article-p13.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,19]]},"references-count":25,"journal-issue":{"issue":"1"},"URL":"https:\/\/doi.org\/10.1556\/1886.2024.00139","relation":{},"ISSN":["2062-509X","2062-8633"],"issn-type":[{"value":"2062-509X","type":"print"},{"value":"2062-8633","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,3,19]]}}}