{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T16:58:15Z","timestamp":1791305895783,"version":"4.3.1"},"reference-count":76,"publisher":"Akademiai Kiado Zrt.","license":[{"start":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T00:00:00Z","timestamp":1791244800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["www.akjournals.com"],"crossmark-restriction":true},"short-container-title":["JBA"],"published-print":{"date-parts":[[2026,10,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Disordered gambling has been linked to impairments in goal-directed (model-based) control and reinforcement learning.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Here we investigated the potential neural basis of this impairment using a sequential reinforcement learning task (modified two-step-task), computational modeling, and functional magnetic resonance imaging (fMRI) in individuals exhibiting symptoms of disordered gambling (GD) and matched healthy controls (HC,\n                      <jats:italic>n<\/jats:italic>\n                      = 30 per group).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Model-agnostic analyses replicated the effects of reduced performance and reduced model-based control in the gambling group, both in terms of choice and response time effects. Computational modeling of choice behavior confirmed that this effect was due to reduced model-based control in the gambling group. Analyses of choices and response times using drift diffusion modeling revealed a more complex pattern, where behavioral impairments in the gambling group were linked to changes across several parameters reflecting drift rate modulation and asymptote, as well as non-decision time. Despite these pronounced behavioral differences, the gambling group exhibited largely intact neural effects related to the task transition structure, reward feedback and trial-to-trial behavioral adjustments.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>Results are discussed with respect to current neurocomputational models of behavioral dysregulation in disordered gambling.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1556\/2006.2025.00424","type":"journal-article","created":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T16:48:46Z","timestamp":1791305326000},"update-policy":"https:\/\/doi.org\/10.1556\/policypage.crossmark.crossref.2","source":"Crossref","is-referenced-by-count":0,"title":["Reduced model-based control in gambling disorder despite seemingly intact neural value and task structure representations"],"prefix":"10.1556","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0422-8160","authenticated-orcid":true,"given":"Angela","family":"Brands","sequence":"first","affiliation":[{"name":"Department of Psychology, Biological Psychology, University of Cologne, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4002-4651","authenticated-orcid":true,"given":"Kilian","family":"Knauth","sequence":"additional","affiliation":[{"name":"Department of Psychology, Biological Psychology, University of Cologne, Germany"},{"name":"Department of Psychiatry and Psychotherapy, University of Bonn, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3411-7867","authenticated-orcid":true,"given":"David","family":"Mathar","sequence":"additional","affiliation":[{"name":"Department of Psychology, Biological Psychology, University of Cologne, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4443-9926","authenticated-orcid":true,"given":"Sangil","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Psychological and Brain Sciences, Boston University, Boston, Massachusetts, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3698-7789","authenticated-orcid":true,"given":"Bojana","family":"Kuzmanovic","sequence":"additional","affiliation":[{"name":"Max Planck Institute for Metabolism Research, Cologne, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5072-2149","authenticated-orcid":true,"given":"Marc","family":"Tittgemeyer","sequence":"additional","affiliation":[{"name":"Max Planck Institute for Metabolism Research, Cologne, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0195-5357","authenticated-orcid":true,"given":"Jan","family":"Peters","sequence":"additional","affiliation":[{"name":"Department of Psychology, Biological Psychology, University of Cologne, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"425","reference":[{"issue":"10","key":"B1","series-title":"Nature Neuroscience","doi-asserted-by":"publisher","first-page":"1338","DOI":"10.1038\/nn.2921","article-title":"Medial prefrontal cortex as an action-outcome predictor","volume":"14","author":"Alexander, W. 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