{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T03:15:47Z","timestamp":1787022947824,"version":"build-2736575974"},"reference-count":22,"publisher":"Akademiai Kiado Zrt.","issue":"3","license":[{"start":{"date-parts":[[2016,7,20]],"date-time":"2016-07-20T00:00:00Z","timestamp":1468972800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":["J Behav Addict"],"published-print":{"date-parts":[[2016,7,20]]},"abstract":"\n Background<\/jats:title>\n How best to conceptualize problematic pornography use (PPU) and intervene most effectively remain debated, with obsessive\u2013compulsive disorder (OCD) and addiction frameworks. We investigated the efficacy of the serotonin-reuptake inhibitor paroxetine in combination with cognitive-behavioral therapy in the treatment of problematic pornography use (PPU).<\/jats:p>\n <\/jats:sec>\n \n Case presentation<\/jats:title>\n Three heterosexual males with PPU were treated with cognitive-behavioral therapy and paroxetine. Frequency of pornography use, other sexual behaviors, and anxiety were assessed during treatment.<\/jats:p>\n <\/jats:sec>\n \n Discussion<\/jats:title>\n Paroxetine treatment, although seemingly initially effective in reducing pornography use and anxiety, appeared related to new compulsive sexual behaviors after 3 months.<\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n Paroxetine may hold promise for short-term reduction of PPU and related anxiety, but new potentially distressing sexual behaviors may emerge. The cases suggest that PPU may arise from multiple domains. We propose an explanation of the effects based on recent neuroscientific research on sexual behaviors and alcohol use.<\/jats:p>\n <\/jats:sec>","DOI":"10.1556\/2006.5.2016.046","type":"journal-article","created":{"date-parts":[[2016,7,21]],"date-time":"2016-07-21T06:55:33Z","timestamp":1469084133000},"page":"529-532","update-policy":"https:\/\/doi.org\/10.1556\/policypage.crossmark.crossref.2","source":"Crossref","is-referenced-by-count":92,"title":["Paroxetine Treatment of Problematic Pornography Use: A Case Series"],"prefix":"10.1556","volume":"5","author":[{"given":"Mateusz","family":"Gola","sequence":"first","affiliation":[{"name":"Swartz Center for Computational Neuroscience, Institute for Neural Computations, University of California San Diego, San Diego, CA, USA"},{"name":"Institute of Psychology, Polish Academy of Sciences, Warsaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc N.","family":"Potenza","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Child Study Center and CASAColumbia, Yale School of Medicine, New Haven, CT, USA"},{"name":"Department of Neurobiology, Child Study Center and CASAColumbia, Yale School of Medicine, New Haven, CT, USA"},{"name":"Connecticut Mental Health Center, New Haven, CT, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"425","reference":[{"issue":"9","key":"B1","series-title":"Neuropsychopharmacology,","first-page":"1837","article-title":"Neural correlates of antidepressant-related sexual dysfunction: A placebo-controlled fMRI study on healthy males under subchronic paroxetine and bupropion","volume":"36","author":"Abler, B.","year":"2011","unstructured":"Abler, B.\n , \n \n Seeringer, A.\n , \n \n Hartmann, A.\n , \n \n Gr\u00f6n, G.\n , \n \n Metzger, C.\n , \n \n Walter, M.\n , & \n \n Stingl, J.\n (2011). Neural correlates of antidepressant-related sexual dysfunction: A placebo-controlled fMRI study on healthy males under subchronic paroxetine and bupropion. Neuropsychopharmacology,36(9), 1837\u20131847. doi: 10.1038\/npp.2011.66"},{"key":"B2","article-title":"Cognitive-behavioral therapy for bipolar disorder","author":"Basco, M.\u00a0R.","year":"2005","unstructured":"Basco, M.\u00a0R.\n , & \n \n Rush, A.\u00a0J.\n (2005). Cognitive-behavioral therapy for bipolar disorder. Retrieved from https:\/\/books.google.com\/books?hl=pl&lr=&id=o2oDxFGr9C4C&oi=fnd&pg=PA1&dq=monica+ramirez+basco&ots=VElWrbGZJq&sig=yHktb8A9D72YMgLnUT8K9TB02NI"},{"issue":"2","key":"B100","series-title":"Mayo Clinic Proceedings,","first-page":"226","article-title":"Internet sex addiction treated with naltrexone","volume":"83","author":"Bostwick, J.\u00a0M., & Bucci, J.\u00a0A.","year":"2008","unstructured":"Bostwick, J.\u00a0M., & Bucci, J.\u00a0A.\n (2008). Internet sex addiction treated with naltrexone. Mayo Clinic Proceedings,83(2), 226\u2013230. doi: 10.4065\/83.2.226"},{"issue":"2","key":"B3","series-title":"Journal of Psychology & Human Sexuality,","first-page":"37","article-title":"Compulsive sexual behavior: New concepts and treatments","volume":"4","author":"Coleman, E.","year":"1991","unstructured":"Coleman, E.\n (1991). Compulsive sexual behavior: New concepts and treatments. Journal of Psychology & Human Sexuality,4(2), 37\u201352. doi: 10.1300\/J056v04n02_04"},{"key":"B4","series-title":"ABC of Sexual Health","article-title":"Impulsive\/compulsive sexual behaviour","author":"Coleman, E.","year":"2015","unstructured":"Coleman, E.\n (2015). Impulsive\/compulsive sexual behaviour. ABC of Sexual Health. Retrieved from https:\/\/books.google.com\/books?hl=pl&lr=&id=oH64CAAAQBAJ&oi=fnd&pg=PA93&dq=impulsive+compulsive+sexual+behavior&ots=3Ar-41oPQW&sig=OXe63r37ATWqqnc2vTtNEKmggHE"},{"issue":"1","key":"B5","series-title":"American Journal of Psychiatry,","first-page":"40","article-title":"Subthreshold hypomanic symptoms in progression from unipolar major depression to bipolar disorder","volume":"168","author":"Fiedorowicz, J.\u00a0G.","year":"2011","unstructured":"Fiedorowicz, J.\u00a0G.\n , \n \n Endicott, J.\n , \n \n Leon, A.\u00a0C.\n , \n \n Solomon, D.\u00a0A.\n , \n \n Keller, M.\u00a0B.\n , & \n \n Coryell, W.\u00a0H.\n (2011). Subthreshold hypomanic symptoms in progression from unipolar major depression to bipolar disorder. American Journal of Psychiatry,168(1), 40\u201348. doi: 10.1176\/appi.ajp.2010.10030328"},{"key":"B6","series-title":"Biological Psychology","article-title":"Decreased LPP for sexual images in problematic pornography users may be consistent with addiction models. Everything depends on the model (Commentary on Prause, Steele, Staley, Sabatinelli, & Hajcak, 2015)","author":"Gola, M.","year":"2016","unstructured":"Gola, M.\n (2016). Decreased LPP for sexual images in problematic pornography users may be consistent with addiction models. Everything depends on the model (Commentary on Prause, Steele, Staley, Sabatinelli, & Hajcak, 2015). Biological Psychology. doi: 10.1016\/j.biopsycho.2016.05.00327235125"},{"issue":"5","key":"B7","series-title":"The Journal of Sexual Medicine,","first-page":"815","article-title":"What matters: Quantity or quality of pornography use? Psychological and behavioral factors of seeking treatment for problematic pornography use","volume":"13","author":"Gola, M.","year":"2016","unstructured":"Gola, M.\n , \n \n Lewczuk, K.\n , & \n \n Skorko, M.\n (2016). What matters: Quantity or quality of pornography use? Psychological and behavioral factors of seeking treatment for problematic pornography use. The Journal of Sexual Medicine,13(5), 815\u2013824. doi: 10.1016\/j.jsxm.2016.02.16927012817"},{"issue":"46","key":"B8","series-title":"Journal of Neuroscience,","first-page":"15227","article-title":"Sex, impulsivity and anxiety: Interplay between ventral striatum and amygdala reactivity in problematic sexual behaviors","volume":"35","author":"Gola, M.","year":"2015","unstructured":"Gola, M.\n , \n \n Miyakoshi, M.\n , & \n \n Sescousse, G.\n (2015). Sex, impulsivity and anxiety: Interplay between ventral striatum and amygdala reactivity in problematic sexual behaviors. Journal of Neuroscience,35(46), 15227\u201315229. doi: 10.1523\/JNEUROSCI.3273-15.2015"},{"key":"B9","series-title":"Polish Psychiatry,","first-page":"1","article-title":"Polish adaptation of Sexual Addiction Screening Test \u2013 Revised","volume":"41,","author":"Gola, M.","year":"2016","unstructured":"Gola, M.\n , \n \n Skorko, M.\n , \n \n Kowalewska, E.\n , \n \n Ko\u0142odziej, A.\n , \n \n Sikora, M.\n , \n \n Wodyk, M.\n , \n \n Wodyk, Z.\n , & \n \n Dobrowolski, P.\n (2016). Polish adaptation of Sexual Addiction Screening Test \u2013 Revised. Polish Psychiatry,41,1\u201321. doi: 10.12740\/PP\/OnlineFirst\/61414"},{"key":"B105","series-title":"bioRxiv,","first-page":"1","article-title":"Can pornography be addictive? An fMRI study of men seeking treatment for problematic pornography use","volume":"057083,","author":"Gola, M.","year":"2016","unstructured":"Gola, M.\n , \n \n Wordecha, M.\n , \n \n Sescousse, G.\n , \n \n Lew-Starowicz, M.\n , \n \n Kossowski, B.\n , \n \n Wypych, M.\n , \n \n Makeig, S.\n , \n \n Potenza, M.\n , & \n \n Marchewka, A.\n (2016). Can pornography be addictive? An fMRI study of men seeking treatment for problematic pornography use. bioRxiv,057083,1\u201325. doi: 10.1101\/057083"},{"issue":"5","key":"B10","series-title":"Archives of Sexual Behavior,","first-page":"577","article-title":"Gender differences in pornography consumption among young heterosexual Danish adults","volume":"35","author":"Hald, G.\u00a0M.","year":"2006","unstructured":"Hald, G.\u00a0M.\n (2006). Gender differences in pornography consumption among young heterosexual Danish adults. Archives of Sexual Behavior,35(5), 577\u2013585. doi: 10.1007\/s10508-006-9064-0"},{"issue":"1\u20132","key":"B11","series-title":"Sexual Addiction & Compulsivity,","first-page":"27","article-title":"Should hypersexual disorder be classified as an addiction?","volume":"20","author":"Kor, A.","year":"2013","unstructured":"Kor, A.\n , \n \n Fogel, Y.\n , \n \n Reid, R.\u00a0C.\n , & \n \n Potenza, M.\u00a0N.\n (2013). Should hypersexual disorder be classified as an addiction?Sexual Addiction & Compulsivity,20(1\u20132), 27\u201347. doi: 10.1080\/10720162.2013.768132"},{"issue":"12","key":"B102","series-title":"The American Journal of Psychiatry,","first-page":"1260","article-title":"Treatment of compulsive pornography use with naltrexone: A case report","volume":"172","author":"Kraus, S.\u00a0W.","year":"2015","unstructured":"Kraus, S.\u00a0W.\n , \n \n Meshberg-Cohen, S.\n , \n \n Martino, S.\n , \n \n Quinones, L.\u00a0J.\n , & \n \n Potenza, M.\u00a0N.\n (2015). Treatment of compulsive pornography use with naltrexone: A case report. The American Journal of Psychiatry,172(12), 1260\u20131261. doi: 10.1176\/appi.ajp.2015.15060843"},{"key":"B12","series-title":"Addiction","article-title":"Should compulsive sexual behavior be considered an addiction?","author":"Kraus, S.\u00a0W.","year":"2016","unstructured":"Kraus, S.\u00a0W.\n , \n \n Voon, V.\n , & \n \n Potenza, M.\u00a0N.\n (2016). Should compulsive sexual behavior be considered an addiction?Addiction. doi: 10.1111\/add.1329726893127"},{"issue":"3","key":"B13","series-title":"Molecular Psychiatry,","first-page":"348","article-title":"Divergent responses of the amygdala and ventral striatum predict stress-related problem drinking in young adults: Possible differential markers of affective and impulsive pathways of risk for alcohol use disorder","volume":"21","author":"Nikolova, Y.\u00a0S.","year":"2015","unstructured":"Nikolova, Y.\u00a0S.\n , \n \n Knodt, A.\u00a0R.\n , \n \n Radtke, S.\u00a0R.\n , & \n \n Hariri, A.\u00a0R.\n (2015). Divergent responses of the amygdala and ventral striatum predict stress-related problem drinking in young adults: Possible differential markers of affective and impulsive pathways of risk for alcohol use disorder. Molecular Psychiatry,21(3), 348\u2013356. doi: 10.1038\/mp.2015.85"},{"key":"B14","series-title":"Biological Psychology","article-title":"Prause et al. (2015) the latest falsification of addiction predictions","author":"Prause, N.","year":"2016","unstructured":"Prause, N.\n , \n \n Steele, V.\u00a0R.\n , \n \n Staley, C.\n , \n \n Sabatinelli, D.\n , & \n \n Hajcak, G.\n (2016). Prause et al. (2015) the latest falsification of addiction predictions. Biological Psychology. doi: 10.1016\/j.biopsycho.2016.05.00727318185"},{"issue":"1","key":"B101","series-title":"Annals of Clinical Psychiatry,","first-page":"56","article-title":"Augmentation with naltrexone to treat compulsive sexual behavior: A case series","volume":"22","author":"Raymond, N.\u00a0C.","year":"2010","unstructured":"Raymond, N.\u00a0C.\n , \n \n Grant, J.\u00a0E.\n , & \n \n Coleman, E.\n (2010). Augmentation with naltrexone to treat compulsive sexual behavior: A case series. 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Current Medical Research and Opinion,23(4), 701\u2013711. doi: 10.1185\/030079907X178838"},{"issue":"4","key":"B16","series-title":"Neuropsychopharmacology,","first-page":"826","article-title":"Amygdala volume reductions in pediatric patients with obsessive-compulsive disorder treated with paroxetine: Preliminary findings","volume":"29","author":"Szeszko, P.\u00a0R.","year":"2004","unstructured":"Szeszko, P.\u00a0R.\n , \n \n MacMillan, S.\n , \n \n McMeniman, M.\n , \n \n Lorch, E.\n , \n \n Madden, R.\n , \n \n Ivey, J.\n , \n \n Banerjee, S.\u00a0P.\n , \n \n Moore, G.\u00a0J.\n , & \n \n Rosenberg, D.\u00a0R.\n (2004). Amygdala volume reductions in pediatric patients with obsessive-compulsive disorder treated with paroxetine: Preliminary findings. 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The Journal of Neuroscience,35(23), 8896\u20138900. doi: 10.1523\/JNEUROSCI.0737-15.2015"},{"key":"B18","series-title":"Frontiers in Psychology,","first-page":"1","article-title":"Erotic subset for the Nencki Affective Picture System (NAPS ERO): Cross-sexual comparison study","volume":"6","author":"Wierzba, M.","year":"2015","unstructured":"Wierzba, M.\n , \n \n Riegel, M.\n , \n \n Pucz, A.\n , \n \n Le\u015bniewska, Z.\n , \n \n Dragan, W. \u0141\n , \n \n Gola, M.\n , \n \n Jednor\u00f3g, K.\n , & \n \n Marchewka, A.\n (2015). Erotic subset for the Nencki Affective Picture System (NAPS ERO): Cross-sexual comparison study. 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