{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T17:14:27Z","timestamp":1788455667629,"version":"build-2803163510"},"reference-count":50,"publisher":"Akademiai Kiado Zrt.","issue":"2","license":[{"start":{"date-parts":[[2018,6,1]],"date-time":"2018-06-01T00:00:00Z","timestamp":1527811200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":["J Behav Addict"],"published-print":{"date-parts":[[2018,6,5]]},"abstract":"\n Background and aims<\/jats:title>\n This study aimed to evaluate the association between the severity of pathological gambling, serum brain-derived neurotrophic factor (BDNF) level, and the characteristics of quantitative electroencephalography (EEG) in patients with gambling disorder.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n A total of 55 male patients aged 18\u201365 with gambling disorder participated. The severity of pathological gambling was assessed with the nine-item Problem Gambling Severity Index from the Canadian Problem Gambling Index (CPGI-PGSI). The Beck Depression Inventory and Lubben Social Network Scale were also assessed. Serum BDNF levels were assessed from blood samples. The resting-state EEG was recorded while the eyes were closed, and the absolute power of five frequency bands was analyzed: delta (1\u20134\u00a0Hz), theta (4\u20138\u00a0Hz), alpha (8\u201312\u00a0Hz), beta (12\u201330\u00a0Hz), and gamma (30\u201350\u00a0Hz).<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n Serum BDNF level was positively correlated with theta power in the right parietal region (P4, r<\/jats:italic>\u2009=\u2009.403, p<\/jats:italic>\u2009=\u2009.011), beta power in the right parietal region (P4, r<\/jats:italic>\u2009=\u2009.456, p<\/jats:italic>\u2009=\u2009.010), and beta power in the right temporal region (T8, r<\/jats:italic>\u2009=\u2009.421, p<\/jats:italic>\u2009=\u2009.008). Gambling severity (CPGI-PGSI) was positively correlated with absolute beta power in the left frontal region (F7, r<\/jats:italic>\u2009=\u2009.284, p<\/jats:italic>\u2009=\u2009.043) and central region [(C3, r<\/jats:italic>\u2009=\u2009.292, p<\/jats:italic>\u2009=\u2009.038), (C4, r<\/jats:italic>\u2009=\u2009.304, p<\/jats:italic>\u2009=\u2009.030)].<\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n These findings support the hypothesis that right-dominant lateralized correlations between BDNF and beta and theta power reflect right-dominant brain activation in addiction. The positive correlations between beta power and the severity of gambling disorder may be associated with hyperexcitability and increased cravings. These findings contribute to a better understanding of brain-based electrophysiological changes and BDNF levels in patients with pathological gambling.<\/jats:p>\n <\/jats:sec>","DOI":"10.1556\/2006.7.2018.43","type":"journal-article","created":{"date-parts":[[2018,6,5]],"date-time":"2018-06-05T09:00:46Z","timestamp":1528189246000},"page":"331-338","update-policy":"https:\/\/doi.org\/10.1556\/policypage.crossmark.crossref.2","source":"Crossref","is-referenced-by-count":15,"title":["EEG correlates associated with the severity of gambling disorder and serum BDNF levels in patients with gambling disorder"],"prefix":"10.1556","volume":"7","author":[{"given":"Kyoung Min","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Psychiatry, Dankook University Hospital, Cheonan, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sam-Wook","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Korea Institute on Behavioral Addictions, True Mind Mental Health Clinic, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaewon","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Korea Institute on Neuromodulation, Easybrain Center, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun Won","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Catholic University of Daegu School of Medicine, Daegu, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"425","reference":[{"key":"B1","series-title":"Frontal alpha and beta EEG power asymmetry and Iowa Gambling Task performance","author":"Amoss, R.\u00a0T.","year":"2009","unstructured":"Amoss, R.\u00a0T.\n (2009). 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