{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,3]],"date-time":"2022-04-03T00:19:35Z","timestamp":1648945175474},"reference-count":74,"publisher":"Akademiai Kiado Zrt.","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Physiol. Int."],"published-print":{"date-parts":[[2019,7,4]]},"abstract":"<jats:p>Obesity is related to increased oxidative stress. Although low-intensity physical exercise reduces oxidative stress, obese subjects may show exercise intolerance. For these subjects, inspiratory threshold loading could be an alternative tool to reduce oxidative stress. We investigated the effects of inspiratory threshold loading on biomarkers of oxidative stress in obese and normal-weight subjects. Twenty obese (31.4\u2009\u00b1\u20096 years old, 10 men and 10 women, 37.5\u2009\u00b1\u20094.7\u00a0kg\/m<jats:sup>2<\/jats:sup>) and 20 normal-weight (29.4\u2009\u00b1\u20098 years old, 10 men and 10 women, 23.2\u2009\u00b1\u20091.5\u00a0kg\/m<jats:sup>2<\/jats:sup>) subjects matched for <jats:italic>age and gender<\/jats:italic> participated in the study. Maximal inspiratory pressure (MIP) was assessed by a pressure transducer. Blood sampling was performed before and after loading and control protocols to assess thiobarbituric acid reactive substances (TBARS), protein carbonylation, and reduced glutathione. Inspiratory threshold loading was performed at 60% MIP and maintained until task failure. The 30-min control protocol was performed at 0\u00a0cmH<jats:sub>2<\/jats:sub>O. Our results demonstrated that inspiratory threshold loading reduced TBARS across time in obese (6.21\u2009\u00b1\u20092.03 to 4.91\u2009\u00b1\u20092.14\u00a0nmol\u00a0MDA\/ml) and normal-weight subjects (5.60\u2009\u00b1\u20093.58 to 4.69\u2009\u00b1\u20092.80\u00a0nmol\u00a0MDA\/ml; <jats:italic>p<\/jats:italic>\u2009=\u20090.007), but no change was observed in protein carbonyls and glutathione in both groups. The control protocol showed no significant changes in TBARS and protein carbonyls. However, reduced glutathione was increased across time in both groups (obese: from 0.50\u2009\u00b1\u20090.37 to 0.56\u2009\u00b1\u20090.35\u00a0\u03bcmol GSH\/ml; normal-weight: from 0.61\u2009\u00b1\u20090.11 to 0.81\u2009\u00b1\u20090.23\u00a0\u03bcmol GSH\/ml; <jats:italic>p<\/jats:italic>\u2009=\u20090.002). These findings suggest that inspiratory threshold loading could be potentially used as an alternative tool to reduce oxidative stress in both normal-weight and obese individuals.<\/jats:p>","DOI":"10.1556\/2060.106.2019.12","type":"journal-article","created":{"date-parts":[[2019,7,4]],"date-time":"2019-07-04T13:22:45Z","timestamp":1562246565000},"page":"158-167","source":"Crossref","is-referenced-by-count":0,"title":["Inspiratory threshold loading reduces lipoperoxidation in obese and normal-weight subjects"],"prefix":"10.1556","volume":"106","author":[{"given":"CC","family":"Callegaro","sequence":"first","affiliation":[{"name":"1 Laboratory of Physiology and Rehabilitation, Federal University of Santa Maria (UFSM), Santa Maria, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"AD","family":"Hoffmeister","sequence":"additional","affiliation":[{"name":"2 Postgraduate Program in Integral Attention to Health (PPGAIS-UNIJUI\/UNICRUZ), Iju\u00ed, Brazil"},{"name":"3 University of Cruz Alta, Cruz Alta, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"FG","family":"Porto","sequence":"additional","affiliation":[{"name":"2 Postgraduate Program in Integral Attention to Health (PPGAIS-UNIJUI\/UNICRUZ), Iju\u00ed, Brazil"},{"name":"3 University of Cruz Alta, Cruz Alta, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L","family":"Chaves","sequence":"additional","affiliation":[{"name":"3 University of Cruz Alta, Cruz Alta, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"RC","family":"Horn","sequence":"additional","affiliation":[{"name":"2 Postgraduate Program in Integral Attention to Health (PPGAIS-UNIJUI\/UNICRUZ), Iju\u00ed, Brazil"},{"name":"3 University of Cruz Alta, Cruz Alta, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"AC","family":"Tissiani","sequence":"additional","affiliation":[{"name":"3 University of Cruz Alta, Cruz Alta, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"PDA","family":"Bianchi","sequence":"additional","affiliation":[{"name":"3 University of Cruz Alta, Cruz Alta, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JA","family":"Taylor","sequence":"additional","affiliation":[{"name":"4 Harvard Medical School, Boston, MA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","reference":[{"key":"ref441","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1186\/1471-2261-14-185","article-title":"Cardiovascular autonomic dysfunction and oxidative stress induced by fructose overload in an experimental model of hypertension and menopause","volume":"14","author":"Conti","year":"2014","journal-title":"BMC Cardiovasc. Disord."},{"key":"ref311","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1080\/13510002.2016.1223793","article-title":"The diaphragm is better protected from oxidative stress than hindlimb skeletal muscle during CLP-induced sepsis","volume":"22","author":"Talarmin","year":"2017","journal-title":"Redox Rep."},{"key":"ref661","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1111\/j.1469-7793.2001.0277k.x","article-title":"Fatiguing inspiratory muscle work causes reflex reduction in resting leg blood flow in humans","volume":"537","author":"Sheel","year":"2001","journal-title":"J. Physiol."},{"key":"ref51","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.resp.2011.03.001","article-title":"Attenuated inspiratory muscle metaboreflex in endurance-trained individuals","volume":"177","author":"Callegaro","year":"2011","journal-title":"Respir. Physiol. Neurobiol."},{"key":"ref91","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/0003-9861(59)90090-6","article-title":"Tissue sulfhydryl groups","volume":"82","author":"Ellman","year":"1959","journal-title":"Arch. Biochem. Biophys."},{"key":"ref31","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1152\/japplphysiol.00780.2005","article-title":"Respiratory loading intensity and diaphragm oxidative stress: N-acetyl-cysteine effects","volume":"100","author":"Barreiro","year":"2006","journal-title":"J. Appl. Physiol (1985)."},{"key":"ref401","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1590\/S1415-52732010000400013","article-title":"Estresse oxidativo: conceito, implica\u00e7\u00f5es e fatores modulat\u00f3rios","volume":"23","author":"Barbosa","year":"2010","journal-title":"Rev. Nutr."},{"key":"ref131","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.ctcp.2012.04.002","article-title":"Diaphragmatic breathing exercise as a therapeutic intervention for control of oxidative stress in type 2 diabetes mellitus","volume":"18","author":"Hegde","year":"2012","journal-title":"Complement. Ther. Clin. Pract."},{"key":"ref41","first-page":"58","article-title":"Peculiarities of vitamin status in men and women with cardiovascular disease and obesity","volume":"81","author":"Baturin","year":"2012","journal-title":"Vopr. Pitan."},{"key":"ref141","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/0891-5849(95)02043-8","article-title":"Improved analysis of malondialdehyde in human body fluids","volume":"20","author":"Jentzsch","year":"1996","journal-title":"Free Radic. Biol. Med."},{"key":"ref121","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1007\/s00421-015-3317-3","article-title":"Exercise at lunchtime: effect on glycemic control and oxidative stress in middle aged men with type 2 diabetes","volume":"116","author":"Haxhi","year":"2016","journal-title":"Eur. J. Appl. Physiol."},{"key":"ref271","doi-asserted-by":"crossref","first-page":"10497","DOI":"10.3390\/ijms140510497","article-title":"Obesity-associated oxidative stress: strategies finalized to improve redox state","volume":"14","author":"Savini","year":"2013","journal-title":"Int. J. Mol. Sci."},{"key":"ref221","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1097\/gme.0b013e3182038ec1","article-title":"Effect of moderate-intensity exercise on oxidative stress indices in metabolically healthy obese and metabolically unhealthy obese phenotypes in postmenopausal women: a pilot study","volume":"18","author":"Lwow","year":"2011","journal-title":"Menopause."},{"key":"ref191","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1016\/j.clinbiochem.2008.04.024","article-title":"Advanced oxidation protein products (AOPPs) in juvenile overweight and obesity prior to and following weight reduction","volume":"41","author":"Krzystek-Korpacka","year":"2008","journal-title":"Clin. Biochem."},{"key":"ref511","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.ctcp.2012.04.002","article-title":"Diaphragmatic breathing exercise as a therapeutic intervention for control of oxidative stress in type 2 diabetes mellitus","volume":"18","author":"Hegde","year":"2012","journal-title":"Complement. Ther. Clin. Pract."},{"key":"ref571","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1016\/j.clinbiochem.2008.04.024","article-title":"Advanced oxidation protein products (AOPPs) in juvenile overweight and obesity prior to and following weight reduction","volume":"41","author":"Krzystek-Korpacka","year":"2008","journal-title":"Clin. Biochem."},{"key":"ref371","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1111\/j.2047-6310.2012.00135.x","article-title":"The relationship of oxidative stress, adiposity and metabolic risk factors in healthy Black and White American youth","volume":"9","author":"Warolin","year":"2014","journal-title":"Pediatr. Obes."},{"key":"ref161","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1007\/s10238-007-0143-x","article-title":"Advanced oxidation protein products in obese women: its relation to insulin resistance and resistin","volume":"7","author":"Ko\u00e7ak","year":"2007","journal-title":"Clin. Exp. Med."},{"key":"ref551","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1016\/j.mad.2012.07.001","article-title":"Plasma biomarkers of oxidative and AGE-mediated damage of proteins and glycosaminoglycans during healthy ageing: a possible association with ECM metabolism","volume":"133","author":"Komosinska-Vassev","year":"2012","journal-title":"Mech. Ageing Dev."},{"key":"ref201","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3164\/jcbn.12-58","article-title":"Assessment of oxidative stress and antioxidant property using electron spin resonance (ESR) spectroscopy","volume":"52","author":"Lee","year":"2013","journal-title":"J. Clin. Biochem. Nutr."},{"key":"ref331","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1249\/01.MSS.0000126576.53038.E9","article-title":"Obesity exacerbates oxidative stress levels after acute exercise","volume":"36","author":"Vincent","year":"2004","journal-title":"Med. Sci. Sports Exerc."},{"key":"ref21","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1590\/S1415-52732010000400013","article-title":"Estresse oxidativo: conceito, implica\u00e7\u00f5es e fatores modulat\u00f3rios","volume":"23","author":"Barbosa","year":"2010","journal-title":"Rev. Nutr."},{"key":"ref11","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1016\/j.pcad.2013.08.001","article-title":"Evaluation of cardiorespiratory fitness and respiratory muscle function in the obese population","volume":"56","author":"Arena","year":"2014","journal-title":"Prog. Cardiovasc. Dis."},{"key":"ref471","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/0003-9861(59)90090-6","article-title":"Tissue sulfhydryl groups","volume":"82","author":"Ellman","year":"1959","journal-title":"Arch. Biochem. Biophys."},{"key":"ref181","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1007\/s00223-019-00524-1","article-title":"Effects of high-intensity interval running versus cycling on sclerostin, and markers of bone turnover and oxidative stress in young men","volume":"104","author":"Kouvelioti","year":"2019","journal-title":"Calcif. Tissue Int."},{"key":"ref71","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1111\/j.1365-2362.2011.02558.x","article-title":"Predominant role of obesity\/insulin resistance in oxidative stress development","volume":"42","author":"D\u2019Archivio","year":"2012","journal-title":"Eur. J. Clin. Invest."},{"key":"ref491","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1139\/H07-078","article-title":"Gender comparisons of exercise-induced oxidative stress: influence of antioxidant supplementation","volume":"32","author":"Goldfarb","year":"2007","journal-title":"Appl. Physiol. Nutr. Metab."},{"key":"ref171","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1016\/j.mad.2012.07.001","article-title":"Plasma biomarkers of oxidative and AGE-mediated damage of proteins and glycosaminoglycans during healthy ageing: a possible association with ECM metabolism","volume":"133","author":"Komosinska-Vassev","year":"2012","journal-title":"Mech. Ageing Dev."},{"key":"ref81","doi-asserted-by":"crossref","first-page":"405","DOI":"10.3945\/ajcn.112.034918","article-title":"Major metabolite of F2-isoprostane in urine may be a more sensitive biomarker of oxidative stress than isoprostane itself","volume":"96","author":"Dorjgochoo","year":"2012","journal-title":"Am. J. Clin. Nutr."},{"key":"ref721","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1007\/s004210050505","article-title":"Exercise training protects against contraction-induced lipid peroxidation in the diaphragm","volume":"79","author":"Vincent","year":"1999","journal-title":"Eur. J. Appl. Physiol. Occup. Physiol."},{"key":"ref751","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1111\/j.2047-6310.2012.00135.x","article-title":"The relationship of oxidative stress, adiposity and metabolic risk factors in healthy Black and White American youth","volume":"9","author":"Warolin","year":"2014","journal-title":"Pediatr. Obes."},{"key":"ref731","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1007\/PL00013799","article-title":"Short-term exercise training improves diaphragm antioxidant capacity and endurance","volume":"81","author":"Vincent","year":"2000","journal-title":"Eur. J. Appl. Physiol."},{"key":"ref111","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1139\/H07-078","article-title":"Gender comparisons of exercise-induced oxidative stress: influence of antioxidant supplementation","volume":"32","author":"Goldfarb","year":"2007","journal-title":"Appl. Physiol. Nutr. Metab."},{"key":"ref351","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1007\/PL00013799","article-title":"Short-term exercise training improves diaphragm antioxidant capacity and endurance","volume":"81","author":"Vincent","year":"2000","journal-title":"Eur. J. Appl. Physiol."},{"key":"ref211","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1016\/0076-6879(90)86141-H","article-title":"Determination of carbonyl content in oxidatively modified proteins","volume":"186","author":"Levine","year":"1990","journal-title":"Methods Enzymol."},{"key":"ref241","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1590\/S0100-879X1999000600007","article-title":"Reference values for lung function tests. II. Maximal respiratory pressures and voluntary ventilation","volume":"32","author":"Neder","year":"1999","journal-title":"Braz. J. Med. Biol. Res."},{"key":"ref611","doi-asserted-by":"crossref","first-page":"697181","DOI":"10.1155\/2015\/697181","article-title":"Effects of concurrent training on oxidative stress and insulin resistance in obese individuals","volume":"2015","author":"Medeiros","year":"2015","journal-title":"Oxid. Med. Cell. Longev."},{"key":"ref711","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1249\/01.MSS.0000126576.53038.E9","article-title":"Obesity exacerbates oxidative stress levels after acute exercise","volume":"36","author":"Vincent","year":"2004","journal-title":"Med. Sci. Sports Exerc."},{"key":"ref541","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1007\/s10238-007-0143-x","article-title":"Advanced oxidation protein products in obese women: its relation to insulin resistance and resistin","volume":"7","author":"Ko\u00e7ak","year":"2007","journal-title":"Clin. Exp. Med."},{"key":"ref701","doi-asserted-by":"crossref","first-page":"L1013","DOI":"10.1152\/ajplung.00112.2006","article-title":"Nitric oxide production in the ventilatory muscles in response to acute resistive loading","volume":"292","author":"Vassilakopoulos","year":"2007","journal-title":"Am. J. Physiol. Lung Cell. Mol. Physiol."},{"key":"ref61","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1186\/1471-2261-14-185","article-title":"Cardiovascular autonomic dysfunction and oxidative stress induced by fructose overload in an experimental model of hypertension and menopause","volume":"14","author":"Conti","year":"2014","journal-title":"BMC Cardiovasc. Disord."},{"key":"ref521","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/0891-5849(95)02043-8","article-title":"Improved analysis of malondialdehyde in human body fluids","volume":"20","author":"Jentzsch","year":"1996","journal-title":"Free Radic. Biol. Med."},{"key":"ref421","first-page":"58","article-title":"Peculiarities of vitamin status in men and women with cardiovascular disease and obesity","volume":"81","author":"Baturin","year":"2012","journal-title":"Vopr. Pitan."},{"key":"ref651","doi-asserted-by":"crossref","first-page":"10497","DOI":"10.3390\/ijms140510497","article-title":"Obesity-associated oxidative stress: strategies finalized to improve redox state","volume":"14","author":"Savini","year":"2013","journal-title":"Int. J. Mol. Sci."},{"key":"ref281","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1111\/j.1469-7793.2001.0277k.x","article-title":"Fatiguing inspiratory muscle work causes reflex reduction in resting leg blood flow in humans","volume":"537","author":"Sheel","year":"2001","journal-title":"J. Physiol."},{"key":"ref301","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1089\/acm.2007.0567","article-title":"Improvement of glutathione and total antioxidant status with yoga","volume":"13","author":"Sinha","year":"2007","journal-title":"J. Altern. Complement. Med."},{"key":"ref501","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1007\/s00421-015-3317-3","article-title":"Exercise at lunchtime: effect on glycemic control and oxidative stress in middle aged men with type 2 diabetes","volume":"116","author":"Haxhi","year":"2016","journal-title":"Eur. J. Appl. Physiol."},{"key":"ref451","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1111\/j.1365-2362.2011.02558.x","article-title":"Predominant role of obesity\/insulin resistance in oxidative stress development","volume":"42","author":"D\u2019Archivio","year":"2012","journal-title":"Eur. J. Clin. Invest."},{"key":"ref231","doi-asserted-by":"crossref","first-page":"697181","DOI":"10.1155\/2015\/697181","article-title":"Effects of concurrent training on oxidative stress and insulin resistance in obese individuals","volume":"2015","author":"Medeiros","year":"2015","journal-title":"Oxid. Med. Cell. Longev."},{"key":"ref431","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.resp.2011.03.001","article-title":"Attenuated inspiratory muscle metaboreflex in endurance-trained individuals","volume":"177","author":"Callegaro","year":"2011","journal-title":"Respir. Physiol. Neurobiol."},{"key":"ref671","doi-asserted-by":"crossref","first-page":"R1152","DOI":"10.1152\/ajpregu.00376.2010","article-title":"MAPKs and NF-\u03baB differentially regulate cytokine expression in the diaphragm in response to resistive breathing: the role of oxidative stress","volume":"300","author":"Sigala","year":"2011","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"ref681","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1089\/acm.2007.0567","article-title":"Improvement of glutathione and total antioxidant status with yoga","volume":"13","author":"Sinha","year":"2007","journal-title":"J. Altern. Complement. Med."},{"key":"ref251","doi-asserted-by":"crossref","first-page":"2087","DOI":"10.1053\/j.gastro.2007.03.052","article-title":"The epidemiology of obesity.","volume":"132","author":"Ogden","year":"2007","journal-title":"Gastroenterology"},{"key":"ref391","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1016\/j.pcad.2013.08.001","article-title":"Evaluation of cardiorespiratory fitness and respiratory muscle function in the obese population","volume":"56","author":"Arena","year":"2014","journal-title":"Prog. Cardiovasc. Dis."},{"key":"ref101","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1123\/jpah.2017-0606","article-title":"Adherence, adhesion, and dropout reasons of a physical activity program in a high social vulnerability context","volume":"16","author":"Galvim","year":"2019","journal-title":"J. Phys. Act. Health."},{"key":"ref461","doi-asserted-by":"crossref","first-page":"405","DOI":"10.3945\/ajcn.112.034918","article-title":"Major metabolite of F2-isoprostane in urine may be a more sensitive biomarker of oxidative stress than isoprostane itself","volume":"96","author":"Dorjgochoo","year":"2012","journal-title":"Am. J. Clin. Nutr."},{"key":"ref561","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1007\/s00223-019-00524-1","article-title":"Effects of high-intensity interval running versus cycling on sclerostin, and markers of bone turnover and oxidative stress in young men","volume":"104","author":"Kouvelioti","year":"2019","journal-title":"Calcif. Tissue Int."},{"key":"ref411","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1152\/japplphysiol.00780.2005","article-title":"Respiratory loading intensity and diaphragm oxidative stress: N-acetyl-cysteine effects","volume":"100","author":"Barreiro","year":"2006","journal-title":"J. Appl. Physiol (1985)."},{"key":"ref581","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3164\/jcbn.12-58","article-title":"Assessment of oxidative stress and antioxidant property using electron spin resonance (ESR) spectroscopy","volume":"52","author":"Lee","year":"2013","journal-title":"J. Clin. Biochem. Nutr."},{"key":"ref591","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1016\/0076-6879(90)86141-H","article-title":"Determination of carbonyl content in oxidatively modified proteins","volume":"186","author":"Levine","year":"1990","journal-title":"Methods Enzymol."},{"key":"ref261","doi-asserted-by":"crossref","first-page":"411","DOI":"10.3389\/fphys.2016.00411","article-title":"Acute high-intensity interval exercise-induced redox signaling is associated with enhanced insulin sensitivity in obese middle-aged men","volume":"7","author":"Parker","year":"2016","journal-title":"Front. Physiol."},{"key":"ref481","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1123\/jpah.2017-0606","article-title":"Adherence, adhesion, and dropout reasons of a physical activity program in a high social vulnerability context","volume":"16","author":"Galvim","year":"2019","journal-title":"J. Phys. Act. Health."},{"key":"ref151","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1111\/jcmm.13038","article-title":"Gender difference in oxidative stress: a new look at the mechanisms for cardiovascular diseases","volume":"21","author":"Kander","year":"2017","journal-title":"J. Cell Mol. Med."},{"key":"ref361","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1249\/01.MSS.0000152705.77073.B3","article-title":"Obesity and postexercise oxidative stress in older women","volume":"37","author":"Vincent","year":"2005","journal-title":"Med. Sci. Sports Exerc."},{"key":"ref531","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1111\/jcmm.13038","article-title":"Gender difference in oxidative stress: a new look at the mechanisms for cardiovascular diseases","volume":"21","author":"Kander","year":"2017","journal-title":"J. Cell Mol. Med."},{"key":"ref291","doi-asserted-by":"crossref","first-page":"R1152","DOI":"10.1152\/ajpregu.00376.2010","article-title":"MAPKs and NF-\u03baB differentially regulate cytokine expression in the diaphragm in response to resistive breathing: the role of oxidative stress","volume":"300","author":"Sigala","year":"2011","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"ref341","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1007\/s004210050505","article-title":"Exercise training protects against contraction-induced lipid peroxidation in the diaphragm","volume":"79","author":"Vincent","year":"1999","journal-title":"Eur. J. Appl. Physiol. Occup. Physiol."},{"key":"ref691","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1080\/13510002.2016.1223793","article-title":"The diaphragm is better protected from oxidative stress than hindlimb skeletal muscle during CLP-induced sepsis","volume":"22","author":"Talarmin","year":"2017","journal-title":"Redox Rep."},{"key":"ref641","doi-asserted-by":"crossref","first-page":"411","DOI":"10.3389\/fphys.2016.00411","article-title":"Acute high-intensity interval exercise-induced redox signaling is associated with enhanced insulin sensitivity in obese middle-aged men","volume":"7","author":"Parker","year":"2016","journal-title":"Front. Physiol."},{"key":"ref621","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1590\/S0100-879X1999000600007","article-title":"Reference values for lung function tests. II. Maximal respiratory pressures and voluntary ventilation","volume":"32","author":"Neder","year":"1999","journal-title":"Braz. J. Med. Biol. Res."},{"key":"ref741","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1249\/01.MSS.0000152705.77073.B3","article-title":"Obesity and postexercise oxidative stress in older women","volume":"37","author":"Vincent","year":"2005","journal-title":"Med. Sci. Sports Exerc."},{"key":"ref321","doi-asserted-by":"crossref","first-page":"L1013","DOI":"10.1152\/ajplung.00112.2006","article-title":"Nitric oxide production in the ventilatory muscles in response to acute resistive loading","volume":"292","author":"Vassilakopoulos","year":"2007","journal-title":"Am. J. Physiol. Lung Cell. Mol. Physiol."},{"key":"ref601","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1097\/gme.0b013e3182038ec1","article-title":"Effect of moderate-intensity exercise on oxidative stress indices in metabolically healthy obese and metabolically unhealthy obese phenotypes in postmenopausal women: a pilot study","volume":"18","author":"Lwow","year":"2011","journal-title":"Menopause."},{"key":"ref631","doi-asserted-by":"crossref","first-page":"2087","DOI":"10.1053\/j.gastro.2007.03.052","article-title":"The epidemiology of obesity.","volume":"132","author":"Ogden","year":"2007","journal-title":"Gastroenterology"}],"container-title":["Physiology International"],"original-title":[],"link":[{"URL":"https:\/\/www.akademiai.com\/doi\/full-xml\/10.1556\/2060.106.2019.12","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/akjournals.com\/view\/journals\/2060\/106\/2\/article-p158.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.akademiai.com\/doi\/pdf\/10.1556\/2060.106.2019.12","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,11]],"date-time":"2022-02-11T03:29:33Z","timestamp":1644550173000},"score":1,"resource":{"primary":{"URL":"https:\/\/akjournals.com\/doi\/10.1556\/2060.106.2019.12"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6]]},"references-count":74,"journal-issue":{"issue":"2"},"URL":"https:\/\/doi.org\/10.1556\/2060.106.2019.12","relation":{},"ISSN":["2498-602X"],"issn-type":[{"value":"2498-602X","type":"print"}],"subject":[],"published":{"date-parts":[[2019,6]]}}}